Monitoring the clinical introduction of a glutamine and antioxidant solution in critically ill trauma and burn patients

Nutrition

Volumn 24, Issue 11-12, 2008, Pages 1123-1132

  Soguel, Ludivine ^a   Chioléro, René L ^a   Ruffieux, Christiane ^b   Berger, Mette M ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Antioxidant; Critically ill; Enteral nutrition; Outcome; Supplementation

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; BETA CAROTENE; C REACTIVE PROTEIN; GLUTAMINE; SELENIUM; THIAMINE; ZINC;

ADULT; ARTICLE; BRAIN INJURY; BURN; BURN PATIENT; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DOSE COMPARISON; FEMALE; HOSPITAL ADMISSION; HUMAN; INTENSIVE CARE UNIT; LUNG INFECTION; MAJOR CLINICAL STUDY; MALE; PATIENT MONITORING; PRIORITY JOURNAL; SKIN INFECTION; UNIVERSITY HOSPITAL; VITAMIN SUPPLEMENTATION;

ADULT; ANTIOXIDANTS; BURNS; CRITICAL ILLNESS; ENTERAL NUTRITION; FEMALE; GLUTAMINE; HUMANS; MALE; MICRONUTRIENTS; MIDDLE AGED; MULTIPLE ORGAN FAILURE; PROSPECTIVE STUDIES; SELENIUM; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME; VITAMIN E; WOUNDS AND INJURIES; ZINC;

EID: 53449085803     PISSN: 08999007     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nut.2008.05.024     Document Type: Article

References (36)

1. Wernerman J., and Hammarqvist F. Modulation of endogenous glutathione availability. Curr Opin Clin Nutr Metab Care 2 (1999) 487-492
2. Oudemans-van Straaten H.M., Bosman R.J., Treskes M., van der Spoel H.J., and Zandstra D.F. Plasma glutamine depletion and patient outcome in acute ICU admissions. Intensive Care Med 27 (2001) 84-90
3. Berger M.M., and Shenkin A. Update on clinical micronutrient supplementation studies in the critically ill. Curr Opin Clin Nutr Metab Care 109 (2006) 711-716
4. Berger M.M., Cavadini C., Bart A., Mansourian R., Guinchard S., Bartholdi I., et al. Cutaneous zinc and copper losses in burns. Burns 18 (1992) 373-380
5. Berger M.M., Cavadini C., Chioléro R., and Dirren H. Copper, selenium, and zinc status and balances after major trauma. J Trauma 40 (1996) 103-109
6. Stehle P. Nutrition support in critical illness. In: Cynober L., and Moore F.A. (Eds). Nutrition and critical care (2003), S. Karger AG, Basel 57-66 Nestlé nutrition workshop series, volume 8
7. Heyland D.K., Dhaliwalm R., Day A., Drover J., Cote H., and Wischmeyer P. Optimizing the dose of glutamine dipeptides and antioxidants in critically ill patients: a phase I dose-finding study. JPEN 31 (2007) 109-118
8. Wischmeyer P.E. Glutamine: mode of action in critical illness. Crit Care Med 35 suppl (2007) S541-S544
9. Houdijk A.P.J., Nijveldt R.J., and Van Leeuwen P.A.M. Glutamine-enriched enteral feeding in trauma patients: reduced infectious morbidity is not related to changes in endocrine and metabolic responses. JPEN 23 (1999) S52-S58
10. Griffiths R.D., Jones C., and Palmer T.E.A. Six-month outcome of critically ill patients given glutamine-supplemented parenteral nutrition. Nutrition 13 (1997) 295-302
11. Goeters C., Wenn A., Mertes N., Wempe C., Van Aken H., Stehle P., et al. Parenteral L-alanyl-L-glutamine improves 6-month outcome in critically ill patients. Crit Care Med 30 (2002) 2032-2037
12. Dechelotte P., Hasselmann M., Cynober L., Allaouchiche B., Coeffier M., Hecketsweiler B., et al. L-alanyl-L-glutamine dipeptide-supplemented total parenteral nutrition reduces infectious complications and glucose intolerance in critically ill patients: the French controlled, randomized, double-blind, multicenter study. Crit Care Med 34 (2006) 598-604
13. Hall J.C., Dobb G., Hall J., de Sousa R., Brennan L., and McCauley R. A prospective randomized trial of enteral glutamine in critical illness. Intensive Care Med 29 (2003) 1710-1716
14. Berger M.M., Spertini F., Shenkin A., Wardle C., Wiesner L., Schindler C., et al. Trace element supplementation modulates pulmonary infection rates after major burns: a double blind, placebo controlled trial. Am J Clin Nutr 68 (1998) 365-371
15. Angstwurm M.W.A., Schottdorf J., Schopohl J., and Gaertner R. Selenium replacement in patients with severe systemic inflammatory response syndrome improves clinical outcome. Crit Care Med 27 (1999) 1807-1813
16. Angstwurm M.W., Engelmann L., Zimmermann T., Lehmann C., Spes C.H., Abel P., et al. Selenium in Intensive Care (SIC): results of a prospective randomized, placebo-controlled, multiple-center study in patients with severe systemic inflammatory response syndrome, sepsis, and septic shock. Crit Care Med 35 (2007) 118-126
17. Heyland D.K., Dhaliwal R., Suchner U., and Berger M.M. Antioxidant nutrients: a systematic review of trace elements and vitamins in the critically ill. Intensive Care Med 31 (2005) 321-337
18. Jolliet P., Pichard C., Biolo G., Chiolero R., Grimble G., Leverve X., et al. Enteral nutrition in intensive care patients: a practical approach. Clin Nutr 18 (1999) 47-56
19. Villet S., Chioléro R.L., Bollmann M.D., Revelly J.P., Cayeux M.C., Delarue J., et al. Negative impact of hypocaloric feeding and energy balance on clinical outcome in ICU patients. Clin Nutr 24 (2005) 502-509
20. Schroeder J., Alteheld B., Stehle P., Cayeux M.C., Chioléro R.L., and Berger M.M. Safety and intestinal tolerance of high-dose enteral antioxidants and glutamine peptides after upper gastrointestinal surgery. Eur J Clin Nutr 59 (2005) 307-310
21. Melis G.C., Boelens P.G., van der Sijp J.R., Popovici T., De Bandt J.P., Cynober L., et al. The feeding route (enteral or parenteral) affects the plasma response of the dipeptide Ala-Gln and the amino acids glutamine, citrulline and arginine, with the administration of Ala-Gln in preoperative patients. Br J Nutr 94 (2005) 19-26
22. Schulman A.S., Willcutts K.F., Claridge J.A., Evans H.L., Radigan A.E., O'Donnell K.B., et al. Does the addition of glutamine to enteral feeds affect patient mortality?. Crit Care Med 33 (2005) 2501-2506
23. Kajdacsy-Balla Amaral A.C., Andrade F.M., Moreno R., Artigas A., Cantraine F., and Vincent J.L. Use of the sequential organ failure assessment score as a severity score. Intensive Care Med 31 (2005) 243-249
24. Members of the ACCP/SCCM Committee Consensus Conference. American College of Chest Physicians/Society of Critical Care Medicine consensus conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 20 (1992) 864-874
25. Berger M.M., Baines M., Raffoul W., Benathan M., Chiolero R.L., Reeves C., et al. Trace element supplements after major burns modulate antioxidant status and clinical course by way of increased tissue trace element concentration. Am J Clin Nutr 85 (2007) 1293-1300
26. Spindler-Vesel A., Bengmark S., Vovk I., Cerovic O., and Kompan L. Synbiotics, prebiotics, glutamine, or peptide in early enteral nutrition: a randomized study in trauma patients. JPEN 31 (2007) 119-126
27. Kinsky M.P., Milner S.M., Button B., Dubick M.A., and Kramer G.C. Resuscitation of severe thermal injury with hypertonic saline dextran: effects on peripheral and visceral edema in sheep. J Trauma 49 (2000) 844-853
28. Nathens A.B., Neff M.J., Jurkovich G.J., Klotz P., Farver K., Ruzinski J.T., et al. Randomized, prospective trial of antioxidant supplementation in critically ill surgical patients. Ann Surg 236 (2002) 814-822
29. Ligthart-Melis G.C., van de Poll M.C., Dejong C.H., Boelens P.G., Deutz N.E., and van Leeuwen P.A. The route of administration (enteral or parenteral) affects the conversion of isotopically labeled L-[2-15N]glutamine into citrulline and arginine in humans. JPEN 31 (2007) 343-350
30. Garrel D., Patenaude J., Nedelec B., Samson L., Dorais J., Champoux J., et al. Decreased mortality and infectious morbidity in adult burn patients given enteral glutamine supplements: a prospective, controlled, randomized clinical trial. Crit Care Med 31 (2003) 2444-2449
31. Coudray-Lucas C., LeBever H., Cynober L., De Bandt J.P., and Carsin H. Ornithine a-ketoglutarate improves wound healing in severe burn patients: a prospective randomized double-blind trial versus isonitrogenous controls. Crit Care Med 28 (2000) 1772-1776
32. Peng X., Yan H., You Z., Wang P., and Wang S. Clinical and protein metabolic efficacy of glutamine granules-supplemented enteral nutrition in severely burned patients. Burns 31 (2005) 342-346
33. Beale R.J., Sherry T., Lei K., Campbell-Stephen L., McCook J., Smith J., et al. Early enteral supplementation with key pharmaconutrients improves Sequential Organ Failure Assessment score in critically ill patients with sepsis: outcome of a randomized, controlled, double-blind trial. Crit Care Med 36 (2007) 131-144
34. Lavori P.W., Louis T.A., Bailar III J.C., and Polansky M. Designs for experiments-parallel comparisons of treatment. N Engl J Med 309 (1983) 1291-1299
35. Griffiths R.D., and Bongers T. Nutrition support for patients in the intensive care unit. Postgrad Med J 81 (2005) 629-636
36. Moher D., Schulz K.F., and Altman D.G. The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomized trials. Ann Intern Med 134 (2001) 657-662