Mechanisms of epilepsy progression: Current theories and perspectives from neuroplasticity in adulthood and development

Epilepsy Research

Volumn 60, Issue 2-3 SPEC. ISS., 2004, Pages 161-171

  Sutula, Thomas P ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Chronic model; Complex systems; Hippocampus; Intractability; Kindling; Seizures

Indexed keywords

BRAIN FUNCTION; BRAIN INJURY; CORTICAL SYNCHRONIZATION; DISEASE COURSE; DISEASE PREDISPOSITION; EPILEPSY; EPILEPTOGENESIS; GENE MUTATION; GENETIC ANALYSIS; GENETIC HETEROGENEITY; GENETICS; HEREDITY; HIPPOCAMPUS; HUMAN; KINDLING; NERVE CELL; NERVE CELL PLASTICITY; NEUROBIOLOGY; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; REMISSION; SEIZURE; SHORT SURVEY;

ANTICONVULSANTS; DISEASE PROGRESSION; DRUG RESISTANCE; EPILEPSY; HUMANS; NERVOUS SYSTEM; NEURONAL PLASTICITY;

EID: 8444239274     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2004.07.001     Document Type: Short Survey

References (75)

1. V.E. Anderson, W.A. Hauser, and S.S. Rich Genetic heterogeneity and epidemiology of the epilepsies Adv. Neurol. 79 1999 59 73
2. V. Andre, A. Ferrandon, and C. Marescaux The lesional and epileptogenic consequences of lithium-pilocarpine-induced status epilepticus are affected by previous exposure to isolated seizures: effects of amygdala kindling and maximal electroshocks Neuroscience 99 3 2000 469 481
3. J.F. Annegers, W.A. Hauser, and S.P. Coan A population-based study of seizures after traumatic brain injuries NEJM 338 1 1998 20 24
4. J. Bengzon, Z. Kokaia, and E. Elmer Apoptosis and proliferation of dentate gyrus neurons after single and intermittent limbic seizures PNAS (USA) 94 19 1997 10432 10437
5. J. Bengzon, P. Mohapel, C.T. Ekdahl, and O. Lindvall Neuronal apoptosis after brief and prolonged seizures Prog. Brain Res. 135 2002 111 119
6. R.S. Briellmann, S.F. Berkovic, and A. Syngeiotis Seizure-associated hippocampal volume loss: a longitudinal magnetic resonance study of temporal lobe epilepsy Ann. Neurol. 51 5 2002 641 644
7. J.E. Cavazos, I. Das, and T.P. Sutula Neuronal loss induced in limbic pathways by kindling: evidence for induction of hippocampal sclerosis by repeated brief seizures J. Neurosci. 14 5 1994 3106 3121
8. J.E. Cavazos, and T.P. Sutula Progressive neuronal loss induced by kindling: a possible mechanism for mossy fiber synaptic reorganization and hippocampal sclerosis Brain Res. 527 1 1990 1 6
9. Y.C. Chang, A.M. Huang, and Y.M. Kuo Febrile seizures impair memory and cAMP response-element binding protein activation Ann. Neurol. 54 6 2003 706 718
10. C. Charlier, N.A. Singh, and S.G. Ryan A pore mutation in a novel KQT-like potassium channel gene in an idiopathic epilepsy family Nat. Gen. 18 1 1998 53 55
11. J. Cronin, A. Obenhaus, and C. Houser Electrophysiology of dentate granule cells after kainate-induced synaptic reorganization of the mossy fibers Brain Res. 573 2 1992 305 310
12. J.C. Crowley, and L.C. Katz Ocular dominance development revisited Curr. Opin. Neurobiol. 12 1 2002 104 109
13. N.O. Dalby, M. West, and B. Finsen Hilar somatostatin-mRNA containing neurons are preserved after perforant path kindling in the rat Neurosci. Lett. 255 1 1998 45 48
14. J.S. Duncan, and P.J. Thompson The cognitive consequences of epilepsy [Comment] Ann. Neurol. 54 4 2003 421 422
15. J. Engel Jr., S. Wiebe, and J. French Practice parameter: temporal lobe and localized neocortical resections for epilepsy: report of the Quality Standards Subcommittee of the American Academy of Neurology, in association with the American Epilepsy Society and the American Association of Neurological Surgeons Neurology 60 4 2003 538 547
16. D. Fuerst, D. Shah, and A. Shah Hippocampal sclerosis is a progressive disorder: a longitudinal volumetric MRI study Ann. Neurol. 53 3 2003 413 416
17. R. Gallagher Beyond reductionism Science 284 5411 1999 79
18. T.H. Gilbert, D.K. Hannesson, and M.E. Corcoran Hippocampal kindled seizures impair spatial cognition in the Morris water maze Epilepsy Res. 38 2-3 2000 115 125
19. G.V. Goddard, D. McIntyre, and C.K. Leech A permanent change in brain function resulting from daily electrical stimulation Exp. Neur. 25 1969 295 330
20. J. Gorter, P. Goncalves, and E. van Vliet Neuronal death in a rat model of mesial temporal lobe epilepsy is induced by initial status epilepticus and not by later repeated spontaneous seizures Epilepsia 44 2003 647 648
21. K.Z. Haas, E.F. Sperber, and L.A. Opanashuk Resistance of immature hippocampus to morphologic and physiologic alterations following status epilepticus or kindling Hippocampus 11 6 2001 615 625
22. D.K. Hannesson, J. Howland, and M. Pollack Dorsal hippocampal kindling produces a selective and enduring disruption of hippocampally mediated behavior J. Neurosci. 21 12 2001 4443 4450
23. D.K. Hannesson, P. Mohapel, and M.E. Corcoran Dorsal hippocampal kindling selectively impairs spatial learning/short-term memory Hippocampus 11 3 2001 275 286
24. J.L. Hardison, M. Okazaki, and J.V. Nadler Modest increase in extracellular potassium unmasks effect of recurrent mossy fiber growth J. Neurophysiol. 84 5 2000 2380 2389
25. C. Helmstaedter Effects of chronic epilepsy on declarative memory systems Prog. Brain Res. 135 2002 439 453
26. C. Helmstaedter, M. Kurthen, and S. Lux Chronic epilepsy and cognition: a longitudinal study in temporal lobe epilepsy Ann. Neurol. 54 4 2003 425 432
27. B. Hermann, M. Seidenberg, and B. Bell The neurodevelopmental impact of childhood onset temporal lobe epilepsy on brain structure and function and the risk of progressive cognitive effects Prog. Brain Res. 135 2002 429 438
28. D.C. Hesdorffer, W.A. Hauser, and J.F. Annegers Dementia and adult-onset unprovoked seizures Neurology 46 3 1996 727 730
29. L.T. Huang, S.N. Yang, and C.W. Liou Pentylenetetrazol-induced recurrent seizures in rat pups: time course on spatial learning and long-term effects Epilepsia 43 6 2002 567 573
30. H. Jokeit, and A. Ebner Effects of chronic epilepsy on intellectual functions Prog. Brain Res. 135 2002 455 463
31. M.E. Kelly, and D.C. McIntyre Hippocampal kindling protects several structures from the neuronal damage resulting from kainic acid-induced status epilepticus Brain Res. 634 2 1994 245 256
32. C. Koch Complexity and the nervous system Science 284 5411 1999 98 98
33. A. Kondratyev, N. Sahibzada, and K. Gale Electroconvulsive shock exposure prevents neuronal apoptosis after kainic acid-evoked status epilepticus Mol. Brain Res. 91 1-2 2001 1 13
34. R. Kotloski, M. Lynch, and S. Lauersdorf Repeated brief seizures induce progressive hippocampal neuron loss and memory deficits. Prog. Brain Res. 135 2002 95 110
35. D.V. Lewis, D. Barboriak, and J. MacFall Do prolonged febrile seizures produce medial temporal sclerosis? Hypotheses, MRI evidence and unanswered questions Prog. Brain Res. 135 2002 263 278
36. R.S. Liu, L. Lemieux, and G.S. Bell Progressive neocortical damage in epilepsy Ann. Neurol. 53 3 2003 312 324
37. B. Longo, and L.E. Mello Supragranular mossy fiber sprouting is not necessary for spontaneous seizures in the intrahippocampal kainate model of epilepsy in the rat Epilepsy Res. 32 12 1998 172 182
38. W. Löscher, and H. Potschka Role of multidrug transporters in pharmacoresistance to antiepileptic drugs J. Pharm. Exp. Ther. 301 1 2002 7 14
39. M. Lynch, U. Sayin, and J. Bownds Long-term consequences of early postnatal seizures on hippocampal learning and plasticity Eur. J. Neurosci. 12 2000 2252 2264
40. M. Lynch, and T. Sutula Recurrent excitatory connectivity in the dentate gyrus of kindled and kainic acid-treated rats J. Neurophysiol. 83 2 2000 693 704
41. G.W. Mathern, P.D. Adelson, and L.D. Cahan Hippocampal neuron damage in human epilepsy: Meyer's hypothesis revisited Prog. Brain Res. 135 2002 237 251
42. G.W. Mathern, T.L. Babb, and J.P. Leite The pathogenic and progressive features of chronic human hippocampal epilepsy Epilepsy Res. 26 1 1996 151 161
43. D.C. McIntyre, M.E. Kelly, and C. Dufresne FAST and SLOW amygdala kindling rat strains: comparison of amygdala, hippocampal, piriform and perirhinal cortex kindling Epilepsy Res. 35 3 1999 197 209
44. P. Molnar, and J.V. Nadler Mossy fiber-granule cell synapses in the normal and epileptic rat dentate gyrus studied with minimal laser photostimulation J. Neurophysiol. 82 4 1999 1883 1894
45. B.A. Neubauer, A. Hahn, and U. Stephani Clinical spectrum and genetics of Rolandic epilepsy Adv. Neurol. 89 2002 475 479
46. J. Nissinen, K. Lukasiuk, and A. Pitkanen Is mossy fiber sprouting present at the time of the first spontaneous seizures in rat experimental temporal lobe epilepsy? Hippocampus 11 3 2001 299 310
47. J.L. Noebels Modeling human epilepsies in mice Epilepsia 5 2001 11 15
48. J.L. Noebels Ann. Rev. Neurosci. The biology of epilepsy genes 26 2003 599 625
49. E. Olafsson, J. Benedikz, and W.A. Hauser Risk of epilepsy in patients with multiple sclerosis: a population-based study in Iceland Epilepsia 40 6 1999 745 747
50. A. Pitkanen, J. Nissinen, and J. Nairismagi Progression of neuronal damage after status epilepticus and during spontaneous seizures in a rat model of temporal lobe epilepsy Prog. Brain. Res. 135 2002 67 83
51. H. Potschka, M. Fedrowitz, and W. Loscher Multidrug resistance protein MRP2 contributes to blood-brain barrier function and restricts antiepileptic drug activity J. Pharm. Exp. Ther. 306 1 2003 124 131
52. S. Pretel, C.D. Applegate, and D. Piekut Apoptotic and necrotic cell death following kindling induced seizures Acta Histochem. 99 1 1997 71 79
53. R.J. Racine, M. Steingart, and D.C. McIntyre Development of kindling-prone and kindling-resistant rats: selective breeding and electrophysiological studies Epilepsy Res. 35 3 1999 183 195
54. U. Sayin, P. Rutecki, and T. Sutula NMDA-dependent currents in granule cells of the dentate gyrus contribute to induction but not permanence of kindling J. Neurophysiol. 81 2 1999 564 574
55. U. Sayin, S. Osting, and J. Hagen Spontaneous seizures and loss of axo-axonic and axo-somatic inhibition induced by repeated brief seizures in kindled rats J. Neurosci. 23 7 2003 2759 2768
56. U. Sayin, and T. Sutula Febrile seizures during a critical postnatal period increase seizure susceptibility, reduce inhibition, and modify seizure-induced inhibitory plasticity in adulthood Epilepsia 43 Suppl. 7 2002 25
57. P.E. Schauwecker Complications associated with genetic background effects in models of experimental epilepsy Prog. Brain Res. 135 2002 139 148
58. P.E. Schauwecker, and O. Steward Genetic determinants of susceptibility to excitotoxic cell death: implications for gene targeting approaches PNAS (USA) 94 8 1997 4103 4108
59. U. Seegers, H. Potschka, and W. Locher Expression of the multidrug transporter P-glycoprotein in brain capillary endothelial cells and brain parenchyma of amygdala-kindled rats Epilepsia 43 7 2002 675 684
60. U. Seegers, H. Potschka, and W. Locher Transient increase of P-glycoprotein expression in endothelium and parenchyma of limbic brain regions in the kainate model of temporal lobe epilepsy Epilepsy Res. 51 3 2002 257 268
61. F. Sengpiel, and P.C. Kind The role of activity in development of the visual system Curr. Biol. 12 23 2002 818 826
62. C. Shin, J.O. McNamara, and J.I. Morgan Induction of c-fos mRNA expression by afterdischarge in the hippocampus of naive and kindled rats J. Neurochem. 55 3 1990 1050 1055
63. N.A. Singh, C. Charlier, and D. Staufer A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns Nat. Gen. 18 1 1998 25 29
64. R. Sole Signs of life - how complexity invades biology 2000 Basic Books NY, New York
65. C.E. Stafstrom Assessing the behavioral and cognitive effects of seizures on the developing brain Prog. Brain Res. 135 2002 377 390
66. D. Stellwagen, and C.J. Shatz An instructive role for retinal waves in the development of retinogeniculate connectivity Neuron 33 3 2002 357 367
67. T. Sutula Secondary epileptogenesis, kindling, and intractable epilepsy: a reappraisal from the perspective of neural plasticity J.J. Engel P. Schwartzkroin S. Moshe D. Lowenstein Brain Plasticity Epilepsy 45 2001 Academic Press 355 379
68. T. Sutula Seizure-induced axon sprouting: assessing connections between injury, local circuits and epileptogenesis Epilepsy Curr. 2 3 2002 86 91
69. T. Sutula, J. Koch, and G. Golarai NMDA receptor dependence of kindling and mossy fiber sprouting: evidence that the NMDA receptor regulates patterning of hippocampal circuits in the adult brain J. Neurosci. 16 22 1996 7398 7406
70. T. Sutula, S. Lauersdorf, and M. Lynch Deficits in radial arm maze performance in kindled rats: evidence for long-lasting memory dysfunction induced by repeated brief seizures J. Neurosci. 15 12 1995 8295 8301
71. T. Sutula, and A. Pitkanen Do Seizures Damage the Brain Prog. Brain Res 2002 Elsevier Amsterdam
72. E.C. Wirrell Benign epilepsy of childhood with centrotemporal spikes Epilepsia 39 4 1998 S32 S41
73. J.P. Wuarin, and F.E. Dudek Electrographic seizures and new recurrent excitatory circuits in the dentate gyrus of hippocampal slices from kainate-treated epileptic rats J. Neurosci. 16 14 1996 4438 4448
74. L.X. Zhang, M.A. Smith, and X. Li Apoptosis of hippocampal neurons after amygdala kindled seizures Mol. Brain Res. 55 2 1998 198 208
75. X. Zhang, S.S. Cui, and A. Wallace Relations between brain pathology and temporal lobe epilepsy J. Neurosci. 22 14 2002 6052 6061