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Volumn 35, Issue 4, 2004, Pages 918-928

Sensitivity analysis of a novel mathematical model identifies factors determining bone resorption rates

Author keywords

Cellular activity; Feedback mechanisms; Michaelis Menten equations; Osteoclasts; Resorption

Indexed keywords

COLONY STIMULATING FACTOR 1; OSTEOCLAST DIFFERENTIATION FACTOR;

EID: 5344261736     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2004.06.010     Document Type: Article
Times cited : (27)

References (44)
  • 1
    • 0021186093 scopus 로고
    • Reconstruction of the resorptive site in iliac trabecular bone: A kinetic model for bone resorption in 20 normal individuals
    • Eriksen E.F., Melsen F., Mosekilde L. Reconstruction of the resorptive site in iliac trabecular bone: a kinetic model for bone resorption in 20 normal individuals. Metab. Bone Dis. Relat. Res. 5:1984;235-242
    • (1984) Metab. Bone Dis. Relat. Res. , vol.5 , pp. 235-242
    • Eriksen, E.F.1    Melsen, F.2    Mosekilde, L.3
  • 2
    • 0141890514 scopus 로고    scopus 로고
    • Histomorphometric analysis of bone remodeling
    • J.P. Bilezikian, L.G. Raisz, Rodan G.A. second ed. San Diego: Academic Press
    • Ott S.M. Histomorphometric analysis of bone remodeling. Bilezikian J.P., Raisz L.G., Rodan G.A. second ed. Principles of bone biology. vol. 1:2002;303-319 Academic Press, San Diego
    • (2002) Principles of Bone Biology , vol.1 , pp. 303-319
    • Ott, S.M.1
  • 3
    • 0021132962 scopus 로고
    • The cellular basis of bone remodelling: The quantum concept reexamined in light of recent advances in the cell biology of bone
    • Parfitt A.M. The cellular basis of bone remodelling: the quantum concept reexamined in light of recent advances in the cell biology of bone. Calcif. Tissue Int. 36:1984;S37-S45
    • (1984) Calcif. Tissue Int. , vol.36
    • Parfitt, A.M.1
  • 5
    • 0141456343 scopus 로고    scopus 로고
    • Mathematical model predicts a critical role for osteoclast autocrine regulation in the control of bone remodeling
    • Komarova S.V., Smith R.J., Dixon S.J., Sims S.M., Wahl L.M. Mathematical model predicts a critical role for osteoclast autocrine regulation in the control of bone remodeling. Bone. 33:2003;206-215
    • (2003) Bone , vol.33 , pp. 206-215
    • Komarova, S.V.1    Smith, R.J.2    Dixon, S.J.3    Sims, S.M.4    Wahl, L.M.5
  • 6
    • 0012402158 scopus 로고    scopus 로고
    • Determination of individual cell Michaelis-Menten constants
    • Sunray M., Zurgil N., Shafran Y., Deutsch M. Determination of individual cell Michaelis-Menten constants. Cytometry. 47:2002;8-16
    • (2002) Cytometry , vol.47 , pp. 8-16
    • Sunray, M.1    Zurgil, N.2    Shafran, Y.3    Deutsch, M.4
  • 7
    • 0036733587 scopus 로고    scopus 로고
    • CD26/DPPIV signal transduction function, but not proteolytic activity is directly related to its expression level on human Th1 and Th2 cell lines as detected with living cell cytochemistry
    • Boonacker E.P., Wierenga E.A., Smits H.H., Van Noorden C.J.F. CD26/DPPIV signal transduction function, but not proteolytic activity is directly related to its expression level on human Th1 and Th2 cell lines as detected with living cell cytochemistry. J. Histochem. Cytochem. 50:2002;1169-1177
    • (2002) J. Histochem. Cytochem. , vol.50 , pp. 1169-1177
    • Boonacker, E.P.1    Wierenga, E.A.2    Smits, H.H.3    Van Noorden, C.J.F.4
  • 9
    • 0012463208 scopus 로고
    • Some relationships between the biochemistry of photosynthesis and the gas exchange of leaves
    • von Caemmerer S., Farquhar G.D. Some relationships between the biochemistry of photosynthesis and the gas exchange of leaves. Planta. 153:1981;376-387
    • (1981) Planta , vol.153 , pp. 376-387
    • Von Caemmerer, S.1    Farquhar, G.D.2
  • 10
    • 84989078087 scopus 로고
    • 2 concentrations: Has its importance been underestimated?
    • 2 concentrations: has its importance been underestimated? Plant Cell Environ. 14:1991;729-739
    • (1991) Plant Cell Environ. , vol.14 , pp. 729-739
    • Long, S.P.1
  • 11
    • 0034084947 scopus 로고    scopus 로고
    • Can the stomatal changes caused by acute ozone exposure be predicted by changes occurring in the mesophyll? a simplification for models of vegetation response to the global increase in tropospheric elevated ozone episodes
    • Martin M.J., Farage P.K., Humphries S.W., Long S.P. Can the stomatal changes caused by acute ozone exposure be predicted by changes occurring in the mesophyll? A simplification for models of vegetation response to the global increase in tropospheric elevated ozone episodes. Aust. J. Plant Physiol. 27:2000;211-219
    • (2000) Aust. J. Plant Physiol. , vol.27 , pp. 211-219
    • Martin, M.J.1    Farage, P.K.2    Humphries, S.W.3    Long, S.P.4
  • 12
    • 0034233721 scopus 로고    scopus 로고
    • A process-based model to predict the effects of climatic change on leaf isoprene emission rates
    • Martin M.J., Stirling C.M., Humphries S.W., Long S.P. A process-based model to predict the effects of climatic change on leaf isoprene emission rates. Ecol. Model. 131:2000;161-174
    • (2000) Ecol. Model. , vol.131 , pp. 161-174
    • Martin, M.J.1    Stirling, C.M.2    Humphries, S.W.3    Long, S.P.4
  • 13
    • 0034740277 scopus 로고    scopus 로고
    • Simulating the growth response of aspen to elevated ozone: A mechanistic approach to scaling a leaf-level model of ozone effects on photosynthesis to a complex canopy architecture
    • Martin M.J., Host G.E., Lenz K.E., Isebrands J.G. Simulating the growth response of aspen to elevated ozone: a mechanistic approach to scaling a leaf-level model of ozone effects on photosynthesis to a complex canopy architecture. Environ. Pollut. 115:2001;425-436
    • (2001) Environ. Pollut. , vol.115 , pp. 425-436
    • Martin, M.J.1    Host, G.E.2    Lenz, K.E.3    Isebrands, J.G.4
  • 14
    • 0037384936 scopus 로고    scopus 로고
    • A theoretical analysis of the changes in basic multicellular unit activity at menopause
    • Hernandez C.J., Beaupré G.S., Carter D.R. A theoretical analysis of the changes in basic multicellular unit activity at menopause. Bone. 32:2003;357-363
    • (2003) Bone , vol.32 , pp. 357-363
    • Hernandez, C.J.1    Beaupré, G.S.2    Carter, D.R.3
  • 15
    • 0034621881 scopus 로고    scopus 로고
    • Effects of mechanical forces on maintenance and adaptation of form in trabecular bone
    • Huiskes R., Rulmerman R., van Lenthe G.H., Janssen J.D. Effects of mechanical forces on maintenance and adaptation of form in trabecular bone. Nature. 405:2000;704-706
    • (2000) Nature , vol.405 , pp. 704-706
    • Huiskes, R.1    Rulmerman, R.2    Van Lenthe, G.H.3    Janssen, J.D.4
  • 16
    • 0033991384 scopus 로고    scopus 로고
    • Does osteocyte formation cause the nonlinear refilling of osteons?
    • Martin R.B. Does osteocyte formation cause the nonlinear refilling of osteons? Bone. 26:2000;71-78
    • (2000) Bone , vol.26 , pp. 71-78
    • Martin, R.B.1
  • 17
    • 0035076414 scopus 로고    scopus 로고
    • A three-dimensional simulation of age-related remodeling in trabecular bone
    • van der Linden J.C., Verhaar A.N., Weinans H. A three-dimensional simulation of age-related remodeling in trabecular bone. J. Bone Miner. Res. 16:2001;688-696
    • (2001) J. Bone Miner. Res. , vol.16 , pp. 688-696
    • Van Der Linden, J.C.1    Verhaar, A.N.2    Weinans, H.3
  • 19
    • 0033304730 scopus 로고    scopus 로고
    • Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families
    • Suda T., Takahashi N., Udagawa N., Jimi E., Gillespie M.T., Martin T.J. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr. Rev. 20:1999;345-357
    • (1999) Endocr. Rev. , vol.20 , pp. 345-357
    • Suda, T.1    Takahashi, N.2    Udagawa, N.3    Jimi, E.4    Gillespie, M.T.5    Martin, T.J.6
  • 20
    • 0033888977 scopus 로고    scopus 로고
    • Osteoprotegerin ligand modulates murine osteoclast survival in vitro and in vivo
    • Lacey D.L., Tan H.L., Lu L., Kaufman S., Van G., Qiu W., et al. Osteoprotegerin ligand modulates murine osteoclast survival in vitro and in vivo. Am. J. Pathol. 157:2000;435-448
    • (2000) Am. J. Pathol. , vol.157 , pp. 435-448
    • Lacey, D.L.1    Tan, H.L.2    Lu, L.3    Kaufman, S.4    Van, G.5    Qiu, W.6
  • 21
    • 0035206443 scopus 로고    scopus 로고
    • Minireview: The OPG/RANKL/RANK system
    • Khosla S. Minireview: the OPG/RANKL/RANK system. Endocrinology. 142:2001;5050-5055
    • (2001) Endocrinology , vol.142 , pp. 5050-5055
    • Khosla, S.1
  • 22
    • 0027368962 scopus 로고
    • Macrophage colony-stimulating factor stimulates survival and chemotactic behaviour in isolated osteoclasts
    • Fuller K., Owens J.M., Jagger C.J., Wilson A., Moss R., Chambers T.J. Macrophage colony-stimulating factor stimulates survival and chemotactic behaviour in isolated osteoclasts. J. Exp. Med. 178:1993;1733-1744
    • (1993) J. Exp. Med. , vol.178 , pp. 1733-1744
    • Fuller, K.1    Owens, J.M.2    Jagger, C.J.3    Wilson, A.4    Moss, R.5    Chambers, T.J.6
  • 23
    • 0028936354 scopus 로고
    • Macrophage colony-stimulating factor and interleukin-1α maintain the survival of osteoclast-like cells
    • Jimi E., Shuto T., Kuga T. Macrophage colony-stimulating factor and interleukin-1α maintain the survival of osteoclast-like cells. Endocrinology. 136:1995;808-811
    • (1995) Endocrinology , vol.136 , pp. 808-811
    • Jimi, E.1    Shuto, T.2    Kuga, T.3
  • 24
    • 0032494113 scopus 로고    scopus 로고
    • TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts
    • Fuller K., Wong B., Fox S., Choi Y., Chambers T.J. TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts. J. Exp. Med. 188:1998;997-1001
    • (1998) J. Exp. Med. , vol.188 , pp. 997-1001
    • Fuller, K.1    Wong, B.2    Fox, S.3    Choi, Y.4    Chambers, T.J.5
  • 26
    • 0032573559 scopus 로고    scopus 로고
    • Transforming growth factor-β1 increases mRNA levels of osteoclastogenesis inhibitory factor in osteoblastic/stromal cells and inhibits the survival of murine osteoclast-like cells
    • Murakami T., Yamamoto M., Yamamoto M., Ono K., Nishikawa M., Nagata N., et al. Transforming growth factor-β1 increases mRNA levels of osteoclastogenesis inhibitory factor in osteoblastic/stromal cells and inhibits the survival of murine osteoclast-like cells. Biochem. Biophys. Res. 252:1998;747-752
    • (1998) Biochem. Biophys. Res. , vol.252 , pp. 747-752
    • Murakami, T.1    Yamamoto, M.2    Yamamoto, M.3    Ono, K.4    Nishikawa, M.5    Nagata, N.6
  • 27
    • 0032538566 scopus 로고    scopus 로고
    • Transforming growth factor-β stimulates the production of osteoprotegerin/osteoclastogenesis inhibitory factor by bone marrow stromal cells
    • Takai H., Kanematsu M., Yano K., Tsuda E., Higashio K., Ikeda K., et al. Transforming growth factor-β stimulates the production of osteoprotegerin/osteoclastogenesis inhibitory factor by bone marrow stromal cells. J. Biol. Chem. 273:1998;27091-27096
    • (1998) J. Biol. Chem. , vol.273 , pp. 27091-27096
    • Takai, H.1    Kanematsu, M.2    Yano, K.3    Tsuda, E.4    Higashio, K.5    Ikeda, K.6
  • 29
    • 0034873321 scopus 로고    scopus 로고
    • The bone remodeling compartment: A circulatory function for bone lining cells
    • Parfitt A.M. The bone remodeling compartment: a circulatory function for bone lining cells. J. Bone Miner. Res. 16:2002;1583-1585
    • (2002) J. Bone Miner. Res. , vol.16 , pp. 1583-1585
    • Parfitt, A.M.1
  • 30
    • 0033883393 scopus 로고    scopus 로고
    • A model of mechanobiologic and metabolic influences on bone adaptation
    • Hernandez C.J., Beaupré G.S., Carter D.R. A model of mechanobiologic and metabolic influences on bone adaptation. J. Rehabil. Res. Dev. 37:2000;235-244
    • (2000) J. Rehabil. Res. Dev. , vol.37 , pp. 235-244
    • Hernandez, C.J.1    Beaupré, G.S.2    Carter, D.R.3
  • 31
    • 0036140080 scopus 로고    scopus 로고
    • Targeted and nontargeted bone remodeling: Relationship to Basic Multicellular Unit origination and progression
    • Parfitt A.M. Targeted and nontargeted bone remodeling: relationship to Basic Multicellular Unit origination and progression. Bone. 30:2002;5-7
    • (2002) Bone , vol.30 , pp. 5-7
    • Parfitt, A.M.1
  • 32
    • 0025024727 scopus 로고
    • A computerised technique for the quantitative assessment of resorption cavities in trabecular bone
    • Garrahan N.J., Croucher P.I., Compston J.E. A computerised technique for the quantitative assessment of resorption cavities in trabecular bone. Bone. 11:1990;241-245
    • (1990) Bone , vol.11 , pp. 241-245
    • Garrahan, N.J.1    Croucher, P.I.2    Compston, J.E.3
  • 33
    • 0036224335 scopus 로고    scopus 로고
    • The influence of serum cytokines and growth factors on osteoclast formation in Paget's disease
    • Neale S.D., Schulze E., Smith R., Athanasou N.A. The influence of serum cytokines and growth factors on osteoclast formation in Paget's disease. Q. J. Med. 95:2002;233-240
    • (2002) Q. J. Med. , vol.95 , pp. 233-240
    • Neale, S.D.1    Schulze, E.2    Smith, R.3    Athanasou, N.A.4
  • 34
    • 0032145294 scopus 로고    scopus 로고
    • Expression and distribution of transforming growth factor-β isoforms and their signalling receptors in growing human bone
    • Horner A., Kemp P., Summers C., Bord S., Bishop N.J., Kelsall A.W., et al. Expression and distribution of transforming growth factor-β isoforms and their signalling receptors in growing human bone. Bone. 23:1998;95-102
    • (1998) Bone , vol.23 , pp. 95-102
    • Horner, A.1    Kemp, P.2    Summers, C.3    Bord, S.4    Bishop, N.J.5    Kelsall, A.W.6
  • 35
    • 0023037767 scopus 로고
    • Growth factors in bone matrix. Isolation of multiple types by affinity chromatograph on heparin-sepharose
    • Hauschka P.V., Mavrakos A.E., Iafrati M.D., Doleman S.E., Klagsbrun M. Growth factors in bone matrix. Isolation of multiple types by affinity chromatograph on heparin-sepharose. J. Biol. Chem. 261:1986;12665-12674
    • (1986) J. Biol. Chem. , vol.261 , pp. 12665-12674
    • Hauschka, P.V.1    Mavrakos, A.E.2    Iafrati, M.D.3    Doleman, S.E.4    Klagsbrun, M.5
  • 37
    • 0034640848 scopus 로고    scopus 로고
    • Signaling by fibroblast growth factors (FGF) and fibroblast growth factor receptor-2 (FGFR2)-activating mutations blocks mineralization and induces apoptosis in osteoblasts
    • Mansukhani A., Bellosta P., Sahni M., Basilico C. Signaling by fibroblast growth factors (FGF) and fibroblast growth factor receptor-2 (FGFR2)-activating mutations blocks mineralization and induces apoptosis in osteoblasts. J. Cell Biol. 149:2000;1297-1308
    • (2000) J. Cell Biol. , vol.149 , pp. 1297-1308
    • Mansukhani, A.1    Bellosta, P.2    Sahni, M.3    Basilico, C.4
  • 38
    • 0025052204 scopus 로고
    • In vivo effects of human recombinant transforming growth factor beta on bone turnover in normal mice
    • Marcelli C., Yates A.J.P., Mundy G.R. In vivo effects of human recombinant transforming growth factor beta on bone turnover in normal mice. J. Bone Miner. Res. 5:1990;1087-1096
    • (1990) J. Bone Miner. Res. , vol.5 , pp. 1087-1096
    • Marcelli, C.1    Yates, A.J.P.2    Mundy, G.R.3
  • 40
    • 0032710016 scopus 로고    scopus 로고
    • Inhibition of TGFβ receptor signaling in osteoblasts leads to decreased bone remodeling and increased trabecular bone mass
    • Filvaroff E.H., Erlebacher A., Ye J.-Q., Gitelman S.E., Lotz J.C., Heilmann M.R., et al. Inhibition of TGFβ receptor signaling in osteoblasts leads to decreased bone remodeling and increased trabecular bone mass. Development. 126:1999;4267-4279
    • (1999) Development , vol.126 , pp. 4267-4279
    • Filvaroff, E.H.1    Erlebacher, A.2    Ye, J.-Q.3    Gitelman, S.E.4    Lotz, J.C.5    Heilmann, M.R.6
  • 41
    • 0032982437 scopus 로고    scopus 로고
    • Macrophage colony stimulating factor increases bone resorption in dispersed osteoclast cultures by increasing osteoclast size
    • Lees R.L., Heersche J.N. Macrophage colony stimulating factor increases bone resorption in dispersed osteoclast cultures by increasing osteoclast size. J. Bone Miner. Res. 14:1999;937-945
    • (1999) J. Bone Miner. Res. , vol.14 , pp. 937-945
    • Lees, R.L.1    Heersche, J.N.2
  • 42
    • 0035213922 scopus 로고    scopus 로고
    • Estrogen reduces the depth of resorption pits by disturbing the organic bone matrix degradation activity of mature osteoclasts
    • Parikka V., Lehenkari P., Saaai M.-L., Halleen J., Risteli J., Härkönen P., et al. Estrogen reduces the depth of resorption pits by disturbing the organic bone matrix degradation activity of mature osteoclasts. Endocrinology. 142:2001;5371-5378
    • (2001) Endocrinology , vol.142 , pp. 5371-5378
    • Parikka, V.1    Lehenkari, P.2    Saaai, M.-L.3    Halleen, J.4    Risteli, J.5    Härkönen, P.6
  • 43
    • 0025158394 scopus 로고
    • Bone resorption by isolated osteoclasts in living versus devitalized bone: Differences in model and extent and the effects of human recombinant tissue inhibitor of metalloproteinases
    • Shimizu H., Sakamoto M., Sakamoto S. Bone resorption by isolated osteoclasts in living versus devitalized bone: differences in model and extent and the effects of human recombinant tissue inhibitor of metalloproteinases. J. Bone Miner. Res. 5:1990;411-418
    • (1990) J. Bone Miner. Res. , vol.5 , pp. 411-418
    • Shimizu, H.1    Sakamoto, M.2    Sakamoto, S.3
  • 44
    • 0141527583 scopus 로고    scopus 로고
    • Is the paradigm shifting?
    • Heaney R.P. Is the paradigm shifting? Bone. 33:2003;457-465
    • (2003) Bone , vol.33 , pp. 457-465
    • Heaney, R.P.1


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