Soluble cathepsin-L: A marker of bone resorption and bone density?

Journal of Laboratory and Clinical Medicine

Volumn 144, Issue 3, 2004, Pages 163-166

  Lang, T Homas ^a,b   Willinger, Ulrike ^a   Holzer, Gerold ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; CATHEPSIN L; COLLAGEN TYPE 1; OSTEOCALCIN; PARATHYROID HORMONE; SEX HORMONE;

ADULT; AGED; AMINO TERMINAL SEQUENCE; ARTICLE; BLOOD SAMPLING; BONE DENSITY; CONTROLLED STUDY; CROSS LINKING; DUAL ENERGY X RAY ABSORPTIOMETRY; ENZYME LINKED IMMUNOSORBENT ASSAY; EVALUATION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; OSTEOLYSIS; OSTEOPENIA; OSTEOPOROSIS; QUANTITATIVE ANALYSIS; STATISTICAL SIGNIFICANCE;

AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; BONE DENSITY; BONE DISEASES, METABOLIC; BONE RESORPTION; CASE-CONTROL STUDIES; CATHEPSINS; COLLAGEN; COLLAGEN TYPE I; CYSTEINE ENDOPEPTIDASES; FEMALE; HUMANS; MALE; MIDDLE AGED; OSTEOPOROSIS; PEPTIDES; SOLUBILITY;

EID: 5344230689     PISSN: 00222143     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lab.2004.06.001     Document Type: Article

References (11)

1. Leung-Toung R, Li W, Tam TF, Kaarimian K. Thiol-dependent enzymes and their inhibitors: a review. Curr Med Chem 2002979-1002.
2. Ohsawa Y, Nitatori T, Higuchi S, Kominami E, Uchiyama Y. Lysosomal cysteine and aspartic proteinases, acid phosphatase, and an endogenous cysteine proteinase inhibitor, cystatin-beta, in rat osteoclasts. J Histochem Cytochem 1993;41:1075-83.
3. Friedrich B, Jung K, Lein M, Turk I, Rudolph B, Hampel G, et al. Cathepsins B, H, L and cysteine prothease inhibitors in malignant prostatae cell lines, primary cultured prostatic cells and prostatic tissue. Eur J Cancer 199935:138-44.
4. I. Zajc, N. Sever, A. Bervar, T.T. Lah Expression of cysteine peptidase cathepsin L and its inhibitors stefin A and B in relation to tumorigenicity of breast cell lines Cancer Lett 187 2002 185 190
5. Thomssen C, Schmitt M, Goretzki L, Oppelt P, Pache L, Dettmar P, et al. Prognostic value of cysteine peptidase cathepsin B and cathepsin L in human breast cancer. Clin Cancer Res 1995;1:741-6.
6. J. Rozhin, R.L. Wade, K.V. Honn, B.F. Sloane Membrane-associated cathepsin L: a role in metastasis of melanomas Biochem Biophys Res Commun 164 1989 556 561
7. K. Kim, J. Cai, S. Shuja, T. Kuo, M.J. Murnane Presence of activated ras correlates with increased cysteine proteinase activities in human colorectal carcinomas Int J Cancer 79 1998 324 333
8. Y. Ikeda, T. Ikata, T. Mishiro, S. Nakano, M. Ikebe, S. Yasuoka Cathepsins B and L in synovial fluids from patients with rheumatoid arthritis and the effect of cathepsin B on the activation of pro-urokinase J Med Invest 47 2000 61 75
9. J.A. Kanis, J.P. Devogelaer, C. Genari Practical guide for the use of bone mineral measurements in the assessment of treatment of osteoporosis: a position paper of the European Foundation for Osteoporosis and Bone Disease Osteoporosis Int 6 1996 256 261
10. Cranney A, Wells G, Willan A, Griffith L, Zytaruk N, Robinson V, et al. Meta-analyses of therapies for postmenopausal osteoporosis. II. Meta-analysis of alendronate for the treatment of postmenopausal woman. Endocrinol Rev 2002;23:508-16.
11. Genant HK, Lu Y, Mathur AK, Fuerst TP, Cummings SR. Classification based on DXA measurements for assessing the risk for hip fractures. J Bone Mineral Res 1996;11(suppl 1):120.