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Volumn 49, Issue 5, 2008, Pages 768-778

Loss of Sept4 exacerbates liver fibrosis through the dysregulation of hepatic stellate cells

Author keywords

Hepatic stellate cells; Liver fibrosis; Myofibroblastic transformation; Septin

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ALPHA TUBULIN; CARBON TETRACHLORIDE; COLLAGEN; PROTEIN SEPT4; SEPTIN; UNCLASSIFIED DRUG;

EID: 53249151670     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2008.05.026     Document Type: Article
Times cited : (30)

References (21)
  • 1
    • 0842301109 scopus 로고    scopus 로고
    • Structure and function of hepatic stellate cells
    • Senoo H. Structure and function of hepatic stellate cells. Med Electron Microsc 37 (2004) 3-15
    • (2004) Med Electron Microsc , vol.37 , pp. 3-15
    • Senoo, H.1
  • 3
    • 41849117310 scopus 로고    scopus 로고
    • Resolution of liver cirrhosis using vitamin A-coupled liposomes to deliver siRNA against a collagen-specific chaperone
    • Sato Y., Murase K., Kato J., Kobune M., Sato T., Kawano Y., et al. Resolution of liver cirrhosis using vitamin A-coupled liposomes to deliver siRNA against a collagen-specific chaperone. Nat Biotechnol 26 (2008) 431-442
    • (2008) Nat Biotechnol , vol.26 , pp. 431-442
    • Sato, Y.1    Murase, K.2    Kato, J.3    Kobune, M.4    Sato, T.5    Kawano, Y.6
  • 4
    • 30844461245 scopus 로고    scopus 로고
    • Diversity of septin scaffolds
    • Kinoshita M. Diversity of septin scaffolds. Curr Opin Cell Biol 18 (2006) 54-60
    • (2006) Curr Opin Cell Biol , vol.18 , pp. 54-60
    • Kinoshita, M.1
  • 5
    • 20044369350 scopus 로고    scopus 로고
    • Cortical organization by the septin cytoskeleton is essential for structural and mechanical integrity of mammalian spermatozoa
    • Ihara M., Kinoshita A., Yamada S., Tanaka H., Tanigaki A., Kitano A., et al. Cortical organization by the septin cytoskeleton is essential for structural and mechanical integrity of mammalian spermatozoa. Dev Cell 8 (2005) 343-352
    • (2005) Dev Cell , vol.8 , pp. 343-352
    • Ihara, M.1    Kinoshita, A.2    Yamada, S.3    Tanaka, H.4    Tanigaki, A.5    Kitano, A.6
  • 6
    • 33846817344 scopus 로고    scopus 로고
    • Sept4, a component of presynaptic Scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity
    • Ihara M., Yamasaki N., Hagiwara A., Tanigaki A., Kitano A., Hikawa R., et al. Sept4, a component of presynaptic Scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity. Neuron 53 (2007) 519-533
    • (2007) Neuron , vol.53 , pp. 519-533
    • Ihara, M.1    Yamasaki, N.2    Hagiwara, A.3    Tanigaki, A.4    Kitano, A.5    Hikawa, R.6
  • 7
    • 0034739803 scopus 로고    scopus 로고
    • Characterization and expression analysis of two human septin genes, PNUTL1 and PNUTL2
    • Zieger B., Tran H., Hainmann I., Wunderle D., Zgaga-Griesz A., Blaser S., et al. Characterization and expression analysis of two human septin genes, PNUTL1 and PNUTL2. Gene 261 (2000) 197-203
    • (2000) Gene , vol.261 , pp. 197-203
    • Zieger, B.1    Tran, H.2    Hainmann, I.3    Wunderle, D.4    Zgaga-Griesz, A.5    Blaser, S.6
  • 8
    • 34247619364 scopus 로고    scopus 로고
    • Gene expression profiles during hepatic stellate cell activation in culture and in vivo
    • De Minicis S., Seki E., Uchinami H., Kluwe J., Zhang Y., Brenner D.A., et al. Gene expression profiles during hepatic stellate cell activation in culture and in vivo. Gastroenterology 132 (2007) 1937-1946
    • (2007) Gastroenterology , vol.132 , pp. 1937-1946
    • De Minicis, S.1    Seki, E.2    Uchinami, H.3    Kluwe, J.4    Zhang, Y.5    Brenner, D.A.6
  • 9
    • 24944475268 scopus 로고    scopus 로고
    • Isolation and culture of hepatic stellate cells
    • Weiskirchen R., and Gressner A. Isolation and culture of hepatic stellate cells. Methods Mol Med 117 (2005) 99-113
    • (2005) Methods Mol Med , vol.117 , pp. 99-113
    • Weiskirchen, R.1    Gressner, A.2
  • 10
    • 33747797033 scopus 로고    scopus 로고
    • Hepatic stellate cells express synemin, a protein bridging intermediate filaments to focal adhesions
    • Uyama N., Zhao L., Van Rossen E., Hirako Y., Reynaert H., Adams D., et al. Hepatic stellate cells express synemin, a protein bridging intermediate filaments to focal adhesions. Gut 55 (2006) 1276-1289
    • (2006) Gut , vol.55 , pp. 1276-1289
    • Uyama, N.1    Zhao, L.2    Van Rossen, E.3    Hirako, Y.4    Reynaert, H.5    Adams, D.6
  • 11
    • 33845627110 scopus 로고    scopus 로고
    • Effects of retinoic acid on the development of liver fibrosis produced by carbon tetrachloride in mice
    • Wang L., Potter J., Rennie-Tankersley L., Novitskiy G., Sipes J., and Mezey E. Effects of retinoic acid on the development of liver fibrosis produced by carbon tetrachloride in mice. Biochim Biophys Acta 1772 (2007) 66-71
    • (2007) Biochim Biophys Acta , vol.1772 , pp. 66-71
    • Wang, L.1    Potter, J.2    Rennie-Tankersley, L.3    Novitskiy, G.4    Sipes, J.5    Mezey, E.6
  • 12
    • 21844457440 scopus 로고    scopus 로고
    • Attenuated hepatic inflammation and fibrosis in angiotensin type 1a receptor deficient mice
    • Yang L., Bataller R., Dulyx J., Coffman T., Ginès P., Rippe R., et al. Attenuated hepatic inflammation and fibrosis in angiotensin type 1a receptor deficient mice. J Hepatol 43 (2005) 317-323
    • (2005) J Hepatol , vol.43 , pp. 317-323
    • Yang, L.1    Bataller, R.2    Dulyx, J.3    Coffman, T.4    Ginès, P.5    Rippe, R.6
  • 14
    • 36348964151 scopus 로고    scopus 로고
    • Alpha-1 antitrypsin Z protein (PiZ) increases hepatic fibrosis in a murine model of cholestasis
    • Mencin A., Seki E., Osawa Y., Kodama Y., De Minicis S., Knowles M., et al. Alpha-1 antitrypsin Z protein (PiZ) increases hepatic fibrosis in a murine model of cholestasis. Hepatology 46 (2007) 1443-1452
    • (2007) Hepatology , vol.46 , pp. 1443-1452
    • Mencin, A.1    Seki, E.2    Osawa, Y.3    Kodama, Y.4    De Minicis, S.5    Knowles, M.6
  • 15
    • 0038342507 scopus 로고    scopus 로고
    • Association of the cytoskeletal GTP-binding protein Sept4/H5 with cytoplasmic inclusions found in Parkinson's disease and other synucleinopathies
    • Ihara M., Tomimoto H., Kitayama H., Morioka Y., Akiguchi I., Shibasaki H., et al. Association of the cytoskeletal GTP-binding protein Sept4/H5 with cytoplasmic inclusions found in Parkinson's disease and other synucleinopathies. J Biol Chem 278 (2003) 24095-24102
    • (2003) J Biol Chem , vol.278 , pp. 24095-24102
    • Ihara, M.1    Tomimoto, H.2    Kitayama, H.3    Morioka, Y.4    Akiguchi, I.5    Shibasaki, H.6
  • 16
    • 0030943556 scopus 로고    scopus 로고
    • Nedd5, a mammalian septin, is a novel cytoskeletal component interacting with actin-based structures
    • Kinoshita M., Kumar S., Mizoguchi A., Ide C., Kinoshita A., Haraguchi T., et al. Nedd5, a mammalian septin, is a novel cytoskeletal component interacting with actin-based structures. Genes Dev 11 (1997) 1535-1547
    • (1997) Genes Dev , vol.11 , pp. 1535-1547
    • Kinoshita, M.1    Kumar, S.2    Mizoguchi, A.3    Ide, C.4    Kinoshita, A.5    Haraguchi, T.6
  • 17
    • 0041347547 scopus 로고    scopus 로고
    • AT1A-deficient mice show less severe progression of liver fibrosis induced by CCl(4)
    • Kanno K., Tazuma S., and Chayama K. AT1A-deficient mice show less severe progression of liver fibrosis induced by CCl(4). Biochem Biophys Res Commun 308 (2003) 177-183
    • (2003) Biochem Biophys Res Commun , vol.308 , pp. 177-183
    • Kanno, K.1    Tazuma, S.2    Chayama, K.3
  • 18
    • 13844275260 scopus 로고    scopus 로고
    • Cholestatic hepatocellular injury: what do we know and how should we proceed
    • Guicciardi M., and Gores G. Cholestatic hepatocellular injury: what do we know and how should we proceed. J Hepatol 42 (2005) 297-300
    • (2005) J Hepatol , vol.42 , pp. 297-300
    • Guicciardi, M.1    Gores, G.2
  • 20
    • 33751003841 scopus 로고    scopus 로고
    • Sustained activation of Rac1 in hepatic stellate cells promotes liver injury and fibrosis in mice
    • Choi S., Sicklick J., Ma Q., Yang L., Huang J., Qi Y., et al. Sustained activation of Rac1 in hepatic stellate cells promotes liver injury and fibrosis in mice. Hepatology 44 (2006) 1267-1277
    • (2006) Hepatology , vol.44 , pp. 1267-1277
    • Choi, S.1    Sicklick, J.2    Ma, Q.3    Yang, L.4    Huang, J.5    Qi, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.