Sensitive and selective liquid chromatography/tandem mass spectrometry methods for quantitative analysis of 1-methyl-4-phenyl pyridinium (MPP+) in mouse striatal tissue

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 874, Issue 1-2, 2008, Pages 51-56

  Zhang, Mei Yi ^a   Kagan, Natasha ^a   Sung, Mei Li A ^a   Zaleska, Margaret M ^a   Monaghan, Michael ^a  

^a PFIZER INC   (United States)

Author keywords

1 Methyl 4 phenyl pyridinium; 1 Methyl 4 phenyl 1,2,3,6 tetrahydropyridine; Liquid chromatography; Mouse striatal tissue sample preparation; Tandem mass spectrometry

Indexed keywords

MASS SPECTROMETRY;

1-METHYL-4-PHENYL PYRIDINIUM; 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; LIQUID CHROMATOGRAPHY; MOUSE STRIATAL TISSUE SAMPLE PREPARATION; TANDEM MASS SPECTROMETRY;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

1 METHYL 4 PHENYL PYRIDINIUM; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; AMMONIA; BRAIN EXTRACT; DIZOCILPINE; NEUROTOXIN; PERCHLORIC ACID; PYRIDINIUM DERIVATIVE; SELEGILINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CORPUS STRIATUM; DRUG DETERMINATION; DRUG TISSUE LEVEL; ELECTROSPRAY; ION EXCHANGE CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MOUSE; NONHUMAN; PARKINSON DISEASE; PH; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SENSITIVITY AND SPECIFICITY; SEPARATION TECHNIQUE; TANDEM MASS SPECTROMETRY;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; 1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; CHROMATOGRAPHY, LIQUID; CORPUS STRIATUM; MALE; MICE; MICE, INBRED BALB C; MOLECULAR STRUCTURE; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY;

MUS;

EID: 53249115089     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2008.08.030     Document Type: Article

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