Acetylation of N-terminal valine of glycine N-methyltransferase affects enzyme inhibition by folate

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1784, Issue 9, 2008, Pages 1342-1346

  Luka, Zigmund ^a   Loukachevitch, Lioudmila V ^a   Wagner, Conrad ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Binding; Cooperativity; Folate; Glycine N methyltransferase; Inhibition; N terminal acetylation

Indexed keywords

5 METHYLTETRAHYDROFOLATE PENTAGLUTAMATE; 5 METHYLTETRAHYDROFOLIC ACID; FOLIC ACID; GLUTAMIC ACID; GLUTAMIC ACID DERIVATIVE; GLYCINE; METHYLTRANSFERASE; UNCLASSIFIED DRUG; VALINE; ENZYME INHIBITOR; GLYCINE METHYLTRANSFERASE; GNMT PROTEIN, RAT; RECOMBINANT PROTEIN;

ACETYLATION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME KINETICS; ENZYME SUBSTRATE; LIVER HOMOGENATE; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; RAT; ALLOSTERISM; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; GENETICS; IN VITRO STUDY; KINETICS; LIVER; METABOLISM; PROTEIN CONFORMATION;

ACETYLATION; ALLOSTERIC REGULATION; ANIMALS; ENZYME INHIBITORS; FOLIC ACID; GLYCINE N-METHYLTRANSFERASE; KINETICS; LIVER; MODELS, MOLECULAR; PROTEIN CONFORMATION; RATS; RECOMBINANT PROTEINS; VALINE;

EID: 53149154882     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2008.04.016     Document Type: Article

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