5-Methyltetrahydrofolate is bound in intersubunit areas of rat liver folate-binding protein glycine N-methyltransferase

Journal of Biological Chemistry

Volumn 282, Issue 6, 2007, Pages 4069-4075

  Luka, Zigmund ^a   Pakhomova, Svetlana ^c   Loukachevitch, Lioudmila V ^a   Egli, Martin ^a   Newcomer, Marcia E ^c   Wagner, Conrad ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FOLATE INHIBITORS; HYDROPHOBIC CAVITIES; TETRAMERS;

BIOLOGICAL ORGANS; CONFORMATIONS; HYDROPHOBICITY; METABOLISM; RATS; X RAY CRYSTALLOGRAPHY;

ENZYME KINETICS;

5 METHYLTETRAHYDROFOLIC ACID; FOLATE BINDING PROTEIN; GLYCINE METHYLTRANSFERASE; 5-METHYLTETRAHYDROFOLATE; CARRIER PROTEIN; CELL SURFACE RECEPTOR; ENZYME INHIBITOR; FOLATE-BINDING PROTEIN; FOLIC ACID; PROTEIN SUBUNIT; TETRAHYDROFOLIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; ENZYME MECHANISM; ENZYME SPECIFICITY; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN LOCALIZATION; PROTEIN METHYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RAT; STRUCTURE ANALYSIS; ANIMAL; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; LIVER; METABOLISM; PROTEIN ANALYSIS; X RAY CRYSTALLOGRAPHY;

RATTUS;

ANIMALS; BINDING SITES; CARRIER PROTEINS; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; FOLIC ACID; GLYCINE N-METHYLTRANSFERASE; LIVER; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN SUBUNITS; RATS; RECEPTORS, CELL SURFACE; TETRAHYDROFOLATES;

EID: 33947514808     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M610384200     Document Type: Article

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