Comparison of CZE, open-tubular CEC and non-aqueous CE coupled to electrospray MS for impurity profiling of drugs

Electrophoresis

Volumn 29, Issue 17, 2008, Pages 3563-3574

  Vassort, Aurélie ^a,b   Shaw, Paul Nicholas ^a,c   Ferguson, Paul D ^d   Szücs, Roman ^d   Barrett, David A ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b SANOFI   (France)

^c UNIVERSITY OF QUEENSLAND   (Australia)

^d PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

CEC; Impurity profiling; MS; Non aqueous CE; Orthogonality

Indexed keywords

CAPILLARY ELECTROPHORESIS; IMPURITIES;

ANALYTES; CEC; HPLC-ESI MS; IMPURITY PROFILING; MS; NON-AQUEOUS; NON-AQUEOUS CE; ORTHOGONALITY; PHARMACEUTICAL COMPOUNDS; TUBULARS;

ELECTROPHORETIC MOBILITY;

ACETIC ACID; ACETONITRILE; AMMONIUM ACETATE; DRUG; METHANOL; TRIETHYLAMINE;

ARTICLE; CAPILLARY ELECTROCHROMATOGRAPHY; CAPILLARY ELECTROPHORESIS; CAPILLARY ZONE ELECTROPHORESIS; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG IMPURITY; ELECTROPHORETIC MOBILITY; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTERMETHOD COMPARISON; LIPOPHILICITY; PHYSICAL CHEMISTRY; PROCESS OPTIMIZATION; SEPARATION TECHNIQUE;

EID: 53149151068     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.200700769     Document Type: Article

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