Immunosuppressive effect of isopropanol: Down-regulation of cytokine production results from the alteration of discrete transcriptional pathways in activated lymphocytes

Journal of Immunology

Volumn 181, Issue 4, 2008, Pages 2348-2355

  Désy, Olivier ^a   Carignan, Damien ^a   Caruso, Manuel ^a   De Campos Lima, Pedro O ^a  

^a UNIVERSITÉ LAVAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 PROPANOL; ADAPTOR PROTEIN; CD56 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; STAPHYLOCOCCUS ENTEROTOXIN B; TRANSCRIPTION FACTOR NFAT; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; IMMUNOSUPPRESSIVE AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ACTIVITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DOWN REGULATION; FEMALE; GENE TRANSLOCATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOMODULATION; IN VITRO STUDY; INNATE IMMUNITY; MOUSE; NATURAL KILLER CELL; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; SEPTIC SHOCK; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; T LYMPHOCYTE ACTIVATION; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; BLOOD; CELL CULTURE; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; IMMUNOLOGY; LEUKEMIA CELL LINE; LYMPHOCYTE ACTIVATION; METABOLISM; T LYMPHOCYTE SUBPOPULATION;

2-PROPANOL; ANIMALS; CELLS, CULTURED; CYTOKINES; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTERLEUKIN-2; JURKAT CELLS; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; SHOCK, SEPTIC; SIGNAL TRANSDUCTION; T-LYMPHOCYTE SUBSETS; TRANSCRIPTION, GENETIC;

EID: 53149126135     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.181.4.2348     Document Type: Article

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