The intermolecular disulfide bridge of human glial cell line-derived neurotrophic factor: Its selective reduction and biological activity of the modified protein

Journal of Protein Chemistry

Volumn 18, Issue 5, 1999, Pages 585-593

  Hui, John O ^a   Woo, Gary ^a   Chow, David T ^a   Katta, Viswanatham ^a   Osslund, Timothy ^a   Haniu, Mitsuru ^a  

^a AMGEN INC   (United States)

Author keywords

Chemical modification; Glial cell line derived neurotrophic factor; HPLC; Partial reduction

Indexed keywords

NEURITE PROMOTING FACTOR;

AMINO ACID SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; DISULFIDE BOND; GLIA CELL; HUMAN; PEPTIDE MAPPING; PROTEIN CONFORMATION;

ALKYLATION; AMINO ACID SEQUENCE; CELL LINE; CHROMATOGRAPHY, GEL; DISULFIDES; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; HUMANS; MOLECULAR SEQUENCE DATA; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; OXIDATION-REDUCTION; PEPTIDE MAPPING; RECOMBINANT PROTEINS;

EID: 53149125130     PISSN: 02778033     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1020607501910     Document Type: Article

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