Synthesis and biological evaluation of amide derivatives of (5,6-dimethoxy-2,3-dihydro-1H-inden-1-yl)acetic acid as anti-inflammatory agents with reduced gastrointestinal ulcerogenecity

European Journal of Medicinal Chemistry

Volumn 43, Issue 10, 2008, Pages 2092-2102

  Sharma, Meenakshi ^a   Ray, S M ^a  

^a BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

Amides; Anti inflammatory; Indene; Ulcerogenecity

Indexed keywords

(5,6 DIMETHOXY 2,3 DIHYDRO 1H INDEN 1 YL)ACETIC ACID; 1 [(5,6 DIMETHOXY 2,3 DIHYDRO 1H INDEN 1 YL)ACETYL]PIPERAZINE; 2 (5,6 DIMETHOXY 2,3 DIHYDRO 1H INDEN 1 YL) N HEXYLACETAMIDE; ACETIC ACID DERIVATIVE; ACETYLSALICYLIC ACID; AMIDE; CARRAGEENAN; INDOMETACIN; N CYCLOHEXYL 2 (5,6 DIMETHOXY 2,3 DIHYDRO 1H INDEN 1 YL)ACETAMIDE; UNCLASSIFIED DRUG;

ADJUVANT ARTHRITIS; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIPYRETIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; FEMALE; FEVER; INFLAMMATION; INTESTINE ULCER; MOUSE; NONHUMAN; PAW EDEMA; REACTION ANALYSIS; STOMACH ULCER; ULCEROGENESIS;

ACETIC ACIDS; AMIDES; ANALGESICS, NON-NARCOTIC; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARTHRITIS; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; FEMALE; GASTROINTESTINAL DISEASES; INDENES; INFLAMMATION; PROADIFEN; RATS; ULCER;

EID: 53149095809     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.08.008     Document Type: Article

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