The perivascular pool of aquaporin-4 mediates the effect of osmotherapy in postischemic cerebral edema

Critical Care Medicine

Volumn 36, Issue 9, 2008, Pages 2634-2640

  Zeynalov, Emil ^a   Chen, Chih Hung ^a,b   Froehner, Stanley C ^c   Adams, Marvin E ^c   Ottersen, Ole Petter ^d   Amiry Moghaddam, Mahmood ^d   Bhardwaj, Anish ^e  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c UNIVERSITY OF WASHINGTON   (United States)

^d UNIVERSITY OF OSLO   (Norway)

^e OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Aquaporins; Astrocyte; Cerebral edema; Focal cerebral ischemia; Infarct; Osmotherapy; Reperfusion; Stroke

Indexed keywords

AQUAPORIN 4; HALOTHANE; PROTEIN; SODIUM CHLORIDE; SYNTROPHIN; WATER; CALCIUM BINDING PROTEIN; MEMBRANE PROTEIN; MUSCLE PROTEIN; SYNTROPHIN ALPHA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY OCCLUSION; ARTICLE; BLOOD BRAIN BARRIER; BRAIN EDEMA; BRAIN REGION; C57BL 6 MOUSE; CEREBROVASCULAR ACCIDENT; CONTINUOUS INFUSION; CONTROLLED STUDY; EXPERIMENTAL ANIMAL; HEMISPHERE; MALE; MIDDLE CEREBRAL ARTERY; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NONHUMAN; OSMOSIS; OSMOTHERAPY; PRIORITY JOURNAL; PROSPECTIVE STUDY; STROKE; TEACHING HOSPITAL; THERAPY; TISSUE INJURY; TREATMENT OUTCOME; WILD TYPE; ANIMAL; BODY WATER; BRAIN ISCHEMIA; C57BL MOUSE; DRUG EFFECT; GENETICS; METABOLISM; MOUSE MUTANT; PATHOPHYSIOLOGY;

ANIMALS; AQUAPORIN 4; BLOOD-BRAIN BARRIER; BODY WATER; BRAIN EDEMA; BRAIN ISCHEMIA; CALCIUM-BINDING PROTEINS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE PROTEINS; OSMOSIS; SALINE SOLUTION, HYPERTONIC;

EID: 53049097949     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3181847853     Document Type: Article

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