Silicon nanopillar substrates for enhancing signal intensity in DNA microarrays

Biosensors and Bioelectronics

Volumn 24, Issue 4, 2008, Pages 723-728

  Murthy, B Ramana ^a   Ng, J K K ^b   Selamat, E S ^b   Balasubramanian, N ^a   Liu, W T ^a,b  

^a INSTITUTE OF MICROELECTRONICS   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Dual substrate pillars; Fluorescence minima; High throughput detection; Nanopillar arrays; Silica chips; SNR enhancement

Indexed keywords

ACIDS; ASPECT RATIO; BIOASSAY; BIOCHIPS; DNA; GENES; LITHOGRAPHY; MICROARRAYS; NONMETALS; NUCLEIC ACIDS; OPTICAL DESIGN; ORGANIC ACIDS; PLANTS (BOTANY); REACTIVE ION ETCHING; SIGNAL TO NOISE RATIO; SILICA; TARGETS; THICK FILMS; THREE DIMENSIONAL;

BACKGROUND NOISES; DEEP-UV LITHOGRAPHY; DISCRIMINATION POWER; DNA MICRO-ARRAYS; DUAL-SUBSTRATE PILLARS; FILM SUBSTRATES; FLUORESCENCE MINIMA; HIGH ASPECT RATIOS; HIGH THROUGHPUT DETECTION; IMMOBILIZATION CAPACITY; NANO-PILLARS; NANOPILLAR ARRAYS; NOISE RATIOS; SENSITIVITY AND SPECIFICITY; SIGNAL INTENSITIES; SILICA CHIPS; SILICON DIOXIDE SUBSTRATES; SILICON DIOXIDES; SILICON-BASED; SNR ENHANCEMENT;

SUBSTRATES;

NANOPARTICLE; NUCLEIC ACID; SILICON; SILICON DIOXIDE;

ARTICLE; COMPARATIVE STUDY; DNA MICROARRAY; HIGH THROUGHPUT SCREENING; HYBRIDIZATION; SENSITIVITY AND SPECIFICITY; SIGNAL NOISE RATIO; SIGNAL TRANSDUCTION;

EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; NANOSTRUCTURES; NANOTECHNOLOGY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PARTICLE SIZE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SILICON DIOXIDE;

EID: 53049095048     PISSN: 09565663     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bios.2008.06.044     Document Type: Article

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