(-)-Epigallocatechin-3-gallate (EGCG) inhibits HGF-induced invasion and metastasis in hypopharyngeal carcinoma cells

Cancer Letters

Volumn 271, Issue 1, 2008, Pages 140-152

  Lim, Young Chang ^a,b   Park, Hun Yi ^c   Hwang, Hye Sook ^c   Kang, Sung Un ^c   Pyun, Jung Hee ^c   Lee, Mi Hye ^c   Choi, Eun Chang ^b   Kim, Chul Ho ^c  

^a Konkuk University School of Medicine   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

^c Ajou University School of Medicine   (South Korea)

Author keywords

EGCG; HGF; Hypopharnygeal carcinoma; MMP; uPA

Indexed keywords

BETA ACTIN; EPIGALLOCATECHIN GALLATE; GELATINASE A; GELATINASE B; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; UROKINASE RECEPTOR;

ANGIOGENESIS; ARTICLE; AUTOPHOSPHORYLATION; CANCER CELL; CANCER INVASION; CANCER PATIENT; CELL MIGRATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; HUMAN; HUMAN CELL; HYPOPHARYNX CARCINOMA; METASTASIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

BASE SEQUENCE; BLOTTING, WESTERN; CATECHIN; CELL LINE, TUMOR; CELL PROLIFERATION; DNA PRIMERS; ENZYME INDUCTION; HEPATOCYTE GROWTH FACTOR; HUMANS; HYPOPHARYNGEAL NEOPLASMS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 53049089163     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2008.05.048     Document Type: Article

References (40)

1. Kim C.H., Kim J.H., Kahng H., and Choi E.C. Change of E-cadherin by hepatocyte growth factor and effects on the prognosis of hypopharyngeal carcinoma. Ann. Surg. Oncol. 14 (2007) 1565-1574
2. Wei W.I. The dilemma of treating hypopharyngeal carcinoma: more or less. Arch. Otolaryngol. Head Neck Surg. 128 (2002) 229-232
3. Lothaire P., de Azambuja E., Dequanter D., Lalami Y., Sotiriou C., Andry G., Castro G., and Awada A. Molecular markers of head and neck squamous cell carcinoma: promising signs in need of prospective evaluation. Head Neck 28 (2006) 256-269
4. Layland M.K., Sessions D.G., and Lenox J. The influence of lymph node metastasis in the treatment of squamous cell carcinoma of the oral cavity, oropharynx, larynx,and hypopharynx: N0 versus N+. Laryngoscope 115 (2005) 629-639
5. Bhowmick N.A., and Moses H.L. Tumor-stroma interactions. Curr. Opin. Genet. Dev. 15 (2005) 97-101
6. Mueller M.M., and Fusenig N.E. Friends or foes-bipolar effects of the tumour stroma in cancer. Nat. Rev. Cancer 4 (2004) 839-849
7. Jiang W.G., Martin T.A., Parr C., Davies G., Matsumoto K., and Nakamura T. Hepatocyte growth factor, its receptor, and their potential value in cancer therapies. Crit. Rev. Oncol. Hematol. 53 (2005) 35-69
8. Di Renzo M.F., Poulsom R., Olivero M., Comoglio P.M., and Lemoine N.R. Expression of the Met/hepatocyte growth factor receptor in human pancreatic cancer. Cancer Res. 55 (1995) 1129-1138
9. Yang C.S., Lambert J.D., Hou Z., Ju J., Lu G., and Hao X. Molecular targets for the cancer preventive activity of tea polyphenols. Mol. Carcinog. 45 (2006) 431-435
10. Yang C.S., Lambert J.D., Ju J., Lu G., and Sang S. Tea and cancer prevention: molecular mechanisms and human relevance. Toxicol. Appl. Pharmacol. 224 (2007) 265-273
11. Afaq F., Adhami V.M., Ahmad N., and Mukhtar H. Inhibition of ultraviolet B-mediated activation of nuclear factor kappaB in normal human epidermal keratinocytes by green tea Constituent (-)-epigallocatechin-3-gallate. Oncogene 22 (2003) 1035-1044
12. Khan N., Afaq F., Saleem M., Ahmad N., and Mukhtar H. Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate. Cancer Res. 66 (2006) 2500-2505
13. Matsumoto K., and Nakamura T. Hepatocyte growth factor and the Met system as a mediator of tumor-stromal interactions. Int. J. Cancer 119 (2006) 477-483
14. Birchmeier C., Birchmeier W., Gherardi G., and Vande Woude G.F. Met, metastasis, motility and more. Nat. Rev. Mol. Cell Biol. 4 (2003) 915-925
15. Gao C.F., and Vande Woude G.F. HGF/SF-Met signaling in tumor progression. Cell Res. 15 (2005) 49-51
16. Maulik G., Kijima T., Ma P.C., Ghosh S.K., Lin J., Shapiro G.I., Schaefer E., Tibaldi E., Johnson B.E., and Salgia R. Modulation of the c-Met/hepatocyte growth factor pathway in small cell lunc cancer. Clin. Cancer Res. 8 (2002) 620-627
17. Michalopoulos G.K. Liver regeneration: molecular mechanisms of growth control. FASEB J. 4 (1990) 176-187
18. Han S.U., Lee J.H., Kim W.H., Cho Y.K., and Kim M.W. Significant correlation between serum level of hepatocyte growth factor and progression of gastric carcinoma. World J. Surg. 23 (1999) 1176-1180
19. Kim C.H., Moon S.K., Bae J.H., Lee J.H., Han J.H., Kim K., and Choi E.C. Expression of hepatocyte growth factor and c-Met in hypopharyngeal squamous cell carcinoma. Acta Otolaryngol. 126 (2006) 88-94
20. Woodhouse E.C., Chuaqui R.F., and Liotta L.A. General mechanisms of metastasis. Cancer 80 (1997) 1529-1537
21. Rosenthal E.L., and Matrisian L.M. Matrix metalloproteases in head and neck cancer. Head Neck 28 (2006) 639-648
22. Yoshizaki T., Maruyama Y., Sato H., and Furukawa M. Expression of tissue inhibitor of matrix metalloproteinase-2 correlates with activation of matrix metalloproteinase-2 and predicts poor prognosis in tongue squamous cell carcinoma. Int. J. Cancer 95 (2001) 44-50
23. Jeon Y.K., Lee B.Y., Kim J.E., Lee S.S., and Kim C.W. Molecular characterization of Epstein-Barr virus and oncoprotein expression in nasopharyngeal carcinoma in Korea. Head Neck 26 (2004) 573-583
24. Pacheco M.M., Kowalski L.P., Nishimoto I.N., and Brentani M.M. Differential expression of c-jun and c-fos mRNAs in squamous cell carcinoma of the head and neck: associations with uPA, gelatinase B, and matrilysin mRNAs. Head Neck 24 (2002) 24-32
25. Dray T.G., Hardin N.J., and Sofferman R.A. Angiogenesis as a prognostic marker in early head and neck cancer. Ann. Otol. Rhinol. Laryngol. 104 (1995) 724-729
26. Folkman J. Tumor angiogenesis: therapeutic implications. N. Engl. J. Med. 285 (1971) 1182-1186
27. Andreasen P.A., Kjoller L., Christensen L., and Duffy M.J. The urokinase-type plasminogen activator system in cancer metastasis: a review. Int. J. Cancer 72 (1997) 1-22
28. Kwaan H.C. The plasminogen-plasmin system in malignancy. Cancer Metastasis Rev. 11 (1992) 291-311
29. Shapiro R.L., Duquette J.G., Roses D.F., Nunes I., Harris M.N., Kamino H., et al. Induction of primary cutaneous melanocytic neoplasms in urokinase-type plasminogen activator (uPA)-deficient and wild-type mice: cellular blue nevi invade but do not progress to malignant melanoma in uPA-deficient animals. Cancer Res. 56 (1996) 3597-3604
30. Folkman J. What is the evidence that tumors are angiogenesis dependent?. J. Natl. Cancer Inst. 82 (1990) 4-6
31. Grigioni W.F., D'Errico A., Fortunato C., Fiorentino M., Mancini A.M., Stetler-Stevenson W.G., et al. Prognosis of gastric carcinoma revealed by interactions between tumor cells and basement membrane. Mod. Pathol. 7 (1994) 220-225
32. Blasi F. The urokinase receptor. A cell surface, regulated chemokine. APMIS 107 (1999) 96-101
33. Duffy M.J., Maguire T.M., McDermott E.W., and O'Higgins N. Urokinase plasminogen activator: a prognostic marker in multiple types of cancer. J. Surg. Oncol. 71 (1999) 130-135
34. Potempa S., and Ridley A.J. Activation of both MAP kinase and phosphatidylinositide 3-kinase by Ras is required for hepatocyte growth factor/scatter factor-induced adherens junction disassembly. Mol. Biol. Cell 9 (1998) 2185-2200
35. Lambert J.D., and Yang C.S. Mechanisms of cancer prevention by tea constituents. J. Nutr. 133 (2003) 3262s-3267s
36. Jung Y.D., and Ellis L.M. Inhibition of tumour invasion and angiogenesis by epigallocatechin gallate (EGCG), a major component of green tea. Int. J. Exp. Pathol. 82 (2001) 309-316
37. Bigleow R.L.H., and Cardelli J.A. The green tea catechins, (-)-Epigallocatechin-3-gallate (EGCG) and (-)-Epicatechin-3-gallate (ECG), inhibit HGF/Met signaling in immortalized and tumorigenic breast epithelial cells. Oncogene 25 (2006) 1922-1930
38. Adhami V.M., Siddiqui I.A., Ahmad N., Gupta S., and Mukhtar H. Oral consumption of green tea polyphenols inhibits insulin-like growth factor-I-induced signaling in an autochthonous mouse model of prostate cancer. Cancer Res. 64 (2004) 8715-8722
39. Fassina G., Vene R., Morini M., Minghelli S., Benelli R., Noonan D.M., and Albini A. Mechanisms of inhibition of tumor angiogenesis and vascular tumor growth by epigallocatechin-3-gallate. Clin. Cancer Res. 10 (2004) 4865-4873
40. Jankun J., Selman S.H., Swercz R., and Skrzypczak-jankun E. Why drinking green tea could prevent cancer. Nature 387 (1997) 561