Identification of drug metabolites in biological matrices by intelligent automated liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry

Volumn 12, Issue 22, 1998, Pages 1756-1760

  Lopez, Linda L ^a   Yu, Xiao ^b   Cui, Donghui ^b   Davis, Margaret R ^b  

^a Thermo Finnigan   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; CHROMATOGRAPHIC ANALYSIS; DATA ACQUISITION; DRUG PRODUCTS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

BIOLOGICAL MATRIXES; DRUG METABOLITES; HIV-PROTEASE INHIBITORS; HPLC DETECTIONS; IN-VITRO; LC-MS-MS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY; REAL-TIME MASS SPECTROMETRY; VITRO INCUBATION;

METABOLITES;

EID: 0031751849     PISSN: 09514198     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-0231(19981130)12:22<1756::aid-rcm381>3.3.co;2-3     Document Type: Article

References (11)

1. rd ASMS Conf. Mass Spectrom. Allied Topics, Atlanta (1995), p. 569.
2. V. K. Boppana, C. Miller-Stein and W. H. Schaefer, J. Chromatogr. B, 678, p. 227-236, (1996).
3. rd ASMS Conf. Mass Spectrom. Allied Topics, Atlanta (1995), p. 649.
4. rd ASMS Conf. Mass Spectrom. Allied Topics, Atlanta (1995), p. 302.
5. th ASMS Conf. Mass Spectrom. Allied Topics, Portland (1996), p. 600.
6. J. L. Josephs, Rapid Commun. Mass Spectrom. 10, 1333-1334 (1996).
7. th ASMS Conf. Mass Spectrom. Allied Topics, Palm Springs (1997), p. 229.
8. P. R. Tiller, Z. El Fallah, V. Wilson, J. Huysman and D. Patel, Rapid Commun. Mass Spectrom. 11, 1570-1574 (1997).
9. P. R. Tiller, A. P. Land, I. Jardine, D. M. Murphy, R. Sozio, A. Ayrton and W. H. Schaefer, J. Chromatogr. A 794, 15-25 (1998).
10. D. M. Drexler and P. R. Tiller, Rapid Commun. Mass Spectrom. 12 895-900 (1998).
11. S. K. Balani, E. J. Woolf, V. L. Hoagland, M. G. Sturgill, P. J. Deutsch, K. C. Yeh and J. H. Lin, Drug Metabolism and Disposition 24, 1389-1394 (1996).