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Volumn 199, Issue 4, 2008, Pages 344.e1-344.e7

The utility of thrombophilia testing in pregnant women with thrombosis: fact or fiction?

Author keywords

inherited thrombophilia; pregnancy; venous thromboembolism

Indexed keywords

ANTICOAGULANT AGENT; ANTITHROMBIN III; BLOOD CLOTTING FACTOR 5 LEIDEN; ESTROGEN; LOW MOLECULAR WEIGHT HEPARIN; PROTEIN C; PROTEIN S; PROTHROMBIN;

EID: 52949150778     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2008.04.051     Document Type: Article
Times cited : (20)

References (67)
  • 1
    • 4143103482 scopus 로고    scopus 로고
    • Hormones and pregnancy: Thromboembolic risks for women
    • Kujovich J.L. Hormones and pregnancy: Thromboembolic risks for women. Br J Haematol 126 (2004) 443-454
    • (2004) Br J Haematol , vol.126 , pp. 443-454
    • Kujovich, J.L.1
  • 2
    • 0038749612 scopus 로고    scopus 로고
    • Pregnancy-related mortality surveillance-United States, 1991-1999
    • Chang J., Elam-Evans L.D., Berg C.J., et al. Pregnancy-related mortality surveillance-United States, 1991-1999. MMWR Surveill Summ 52 (2003) 1-8
    • (2003) MMWR Surveill Summ , vol.52 , pp. 1-8
    • Chang, J.1    Elam-Evans, L.D.2    Berg, C.J.3
  • 4
    • 0023149587 scopus 로고
    • Fibrinolysis in pregnancy: A study of plasminogen activator inhibitors
    • Kruithof E.K., Tran-Thang C., Gudinchet A., et al. Fibrinolysis in pregnancy: A study of plasminogen activator inhibitors. Blood 69 (1987) 460-466
    • (1987) Blood , vol.69 , pp. 460-466
    • Kruithof, E.K.1    Tran-Thang, C.2    Gudinchet, A.3
  • 5
    • 0028810738 scopus 로고
    • World distribution of factor V Leiden
    • Rees D.C., Cox M., and Clegg J.B. World distribution of factor V Leiden. Lancet 346 (1995) 1133-1134
    • (1995) Lancet , vol.346 , pp. 1133-1134
    • Rees, D.C.1    Cox, M.2    Clegg, J.B.3
  • 6
    • 0029846489 scopus 로고    scopus 로고
    • Prevalence of factor V Leiden in a Canadian blood donor population
    • Lee D.H., Henderson P.A., and Blajchman M.A. Prevalence of factor V Leiden in a Canadian blood donor population. CMAJ 155 (1996) 285-289
    • (1996) CMAJ , vol.155 , pp. 285-289
    • Lee, D.H.1    Henderson, P.A.2    Blajchman, M.A.3
  • 7
    • 0031981017 scopus 로고    scopus 로고
    • Geographic distribution of the 20210 G to A prothrombin variant
    • Rosendaal F.R., Doggen C.J., Zivelin A., et al. Geographic distribution of the 20210 G to A prothrombin variant. Thromb Haemost 79 (1998) 706-708
    • (1998) Thromb Haemost , vol.79 , pp. 706-708
    • Rosendaal, F.R.1    Doggen, C.J.2    Zivelin, A.3
  • 8
    • 0034994094 scopus 로고    scopus 로고
    • A study of protein S antigen levels in 3788 healthy volunteers: Influence of age, sex and hormone use, and estimate for prevalence of deficiency state
    • Dykes A.C., et al. A study of protein S antigen levels in 3788 healthy volunteers: Influence of age, sex and hormone use, and estimate for prevalence of deficiency state. Br J Haematol 113 (2001) 636-641
    • (2001) Br J Haematol , vol.113 , pp. 636-641
    • Dykes, A.C.1
  • 9
    • 0023233223 scopus 로고
    • Absence of thrombosis in subjects with heterozygous protein C deficiency
    • Miletich J., Sherman L., and Broze Jr. G. Absence of thrombosis in subjects with heterozygous protein C deficiency. N Engl J Med 317 (1987) 991-996
    • (1987) N Engl J Med , vol.317 , pp. 991-996
    • Miletich, J.1    Sherman, L.2    Broze Jr., G.3
  • 10
    • 0028851046 scopus 로고
    • Prevalence of protein C deficiency in the healthy population
    • Tait R.C., Walker I.D., Reitsma P.H., et al. Prevalence of protein C deficiency in the healthy population. Thromb Haemost 73 (1995) 87-93
    • (1995) Thromb Haemost , vol.73 , pp. 87-93
    • Tait, R.C.1    Walker, I.D.2    Reitsma, P.H.3
  • 11
    • 0018190174 scopus 로고
    • Antithrombin III: Critical review of assay methods. Significance of variations in health and disease
    • Odegard O.R., and Abildgaard U. Antithrombin III: Critical review of assay methods. Significance of variations in health and disease. Haemostasis 7 (1978) 127-134
    • (1978) Haemostasis , vol.7 , pp. 127-134
    • Odegard, O.R.1    Abildgaard, U.2
  • 12
    • 0025061133 scopus 로고
    • Antithrombin III and procoagulant activity: Sex differences and effects of the menopause
    • Meade T.W., et al. Antithrombin III and procoagulant activity: Sex differences and effects of the menopause. Br J Haematol 74 (1990) 77-81
    • (1990) Br J Haematol , vol.74 , pp. 77-81
    • Meade, T.W.1
  • 13
    • 0028234593 scopus 로고
    • Prevalence of antithrombin deficiency in the healthy population
    • Tait R.C., Walker I.D., Perry D.J., et al. Prevalence of antithrombin deficiency in the healthy population. Br J Haematol 87 (1994) 106-112
    • (1994) Br J Haematol , vol.87 , pp. 106-112
    • Tait, R.C.1    Walker, I.D.2    Perry, D.J.3
  • 14
    • 0030929276 scopus 로고    scopus 로고
    • Familial thrombophilia: genetic risk factors and management
    • Makris M., Rosendaal F.R., and Preston F.E. Familial thrombophilia: genetic risk factors and management. J Intern Med Suppl 740 (1997) 9-15
    • (1997) J Intern Med Suppl , vol.740 , pp. 9-15
    • Makris, M.1    Rosendaal, F.R.2    Preston, F.E.3
  • 15
    • 0030951829 scopus 로고    scopus 로고
    • Laboratory evaluation and clinical characteristics of 2,132 consecutive unselected patients with venous thromboembolism-results of the Spanish Multicentric Study on Thrombophilia (EMET-Study)
    • Mateo J., Oliver A., Borrell M., Sala N., and Fontcuberta J. Laboratory evaluation and clinical characteristics of 2,132 consecutive unselected patients with venous thromboembolism-results of the Spanish Multicentric Study on Thrombophilia (EMET-Study). Thromb Haemost 77 (1997) 444-451
    • (1997) Thromb Haemost , vol.77 , pp. 444-451
    • Mateo, J.1    Oliver, A.2    Borrell, M.3    Sala, N.4    Fontcuberta, J.5
  • 16
    • 0345714848 scopus 로고    scopus 로고
    • Low-intensity versus conventional-intensity warfarin for prevention of recurrent venous thromboembolism
    • author reply 2164-7
    • Ridker P.M., Goldhaber S.Z., and Glynn R.J. Low-intensity versus conventional-intensity warfarin for prevention of recurrent venous thromboembolism. N Engl J Med 349 (2003) 2164-2167 author reply 2164-7
    • (2003) N Engl J Med , vol.349 , pp. 2164-2167
    • Ridker, P.M.1    Goldhaber, S.Z.2    Glynn, R.J.3
  • 17
    • 0142182558 scopus 로고    scopus 로고
    • Secondary prevention of venous thromboembolism with the oral direct thrombin inhibitor ximelagatran
    • Schulman S., Wåhlander K., Lundström T., et al. Secondary prevention of venous thromboembolism with the oral direct thrombin inhibitor ximelagatran. N Engl J Med 349 (2003) 1713-1721
    • (2003) N Engl J Med , vol.349 , pp. 1713-1721
    • Schulman, S.1    Wåhlander, K.2    Lundström, T.3
  • 18
    • 0027520285 scopus 로고
    • Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study
    • Koster T., Rosendaal F.R., de Ronde H., Briët E., Vandenbroucke J.P., and Bertina R.M. Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study. Lancet 342 (1993) 1503-1506
    • (1993) Lancet , vol.342 , pp. 1503-1506
    • Koster, T.1    Rosendaal, F.R.2    de Ronde, H.3    Briët, E.4    Vandenbroucke, J.P.5    Bertina, R.M.6
  • 20
    • 0031847816 scopus 로고    scopus 로고
    • Increased risk for venous thrombosis in carriers of the prothrombin G->A20210 gene variant
    • Margaglione M., Brancaccio V., Giuliani N., et al. Increased risk for venous thrombosis in carriers of the prothrombin G->A20210 gene variant. Ann Intern Med 129 (1998) 89-93
    • (1998) Ann Intern Med , vol.129 , pp. 89-93
    • Margaglione, M.1    Brancaccio, V.2    Giuliani, N.3
  • 21
    • 0034840147 scopus 로고    scopus 로고
    • Combined effect of factor V Leiden and prothrombin 20210A on the risk of venous thromboembolism: pooled analysis of 8 case-control studies including 2310 cases and 3204 controls. Study Group for Pooled-Analysis in Venous Thromboembolism
    • Emmerich J., Rosendaal F.R., Catteno M., et al. Combined effect of factor V Leiden and prothrombin 20210A on the risk of venous thromboembolism: pooled analysis of 8 case-control studies including 2310 cases and 3204 controls. Study Group for Pooled-Analysis in Venous Thromboembolism. Thromb Haemost 86 (2001) 809-816
    • (2001) Thromb Haemost , vol.86 , pp. 809-816
    • Emmerich, J.1    Rosendaal, F.R.2    Catteno, M.3
  • 22
    • 0034628535 scopus 로고    scopus 로고
    • Prothrombin and factor V mutations in women with a history of thrombosis during pregnancy and the puerperium
    • Gerhardt A., Scharf R.E., Beckmann M.W., et al. Prothrombin and factor V mutations in women with a history of thrombosis during pregnancy and the puerperium. N Engl J Med 342 (2000) 374-380
    • (2000) N Engl J Med , vol.342 , pp. 374-380
    • Gerhardt, A.1    Scharf, R.E.2    Beckmann, M.W.3
  • 24
    • 0029974036 scopus 로고    scopus 로고
    • Determinants and vitamin responsiveness of intermediate hyperhomocysteinemia (> or = 40 micromol/liter). The Hordaland Homocysteine Study
    • Guttormsen A.B., Ueland P.M., Nesthus I., et al. Determinants and vitamin responsiveness of intermediate hyperhomocysteinemia (> or = 40 micromol/liter). The Hordaland Homocysteine Study. J Clin Invest 98 (1996) 2174-2183
    • (1996) J Clin Invest , vol.98 , pp. 2174-2183
    • Guttormsen, A.B.1    Ueland, P.M.2    Nesthus, I.3
  • 25
    • 0038446637 scopus 로고    scopus 로고
    • Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults
    • Kluijtmans L.A., Young I.S., Boreham C.A., et al. Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults. Blood 101 (2003) 2483-2488
    • (2003) Blood , vol.101 , pp. 2483-2488
    • Kluijtmans, L.A.1    Young, I.S.2    Boreham, C.A.3
  • 26
    • 0032569645 scopus 로고    scopus 로고
    • Meta-analysis of hyperhomocysteinemia as a risk factor for venous thromboembolic disease
    • Ray J.G. Meta-analysis of hyperhomocysteinemia as a risk factor for venous thromboembolic disease. Arch Intern Med 158 (1998) 2101-2106
    • (1998) Arch Intern Med , vol.158 , pp. 2101-2106
    • Ray, J.G.1
  • 28
    • 0037373178 scopus 로고    scopus 로고
    • Serum homocysteine, thermolabile variant of methylene tetrahydrofolate reductase (MTHFR), and venous thromboembolism: Longitudinal Investigation of Thromboembolism Etiology (LITE)
    • Tsai A.W., Cushman M., Tsai M.Y., et al. Serum homocysteine, thermolabile variant of methylene tetrahydrofolate reductase (MTHFR), and venous thromboembolism: Longitudinal Investigation of Thromboembolism Etiology (LITE). Am J Hematol 72 (2003) 192-200
    • (2003) Am J Hematol , vol.72 , pp. 192-200
    • Tsai, A.W.1    Cushman, M.2    Tsai, M.Y.3
  • 29
    • 33947251140 scopus 로고    scopus 로고
    • No association between the common MTHFR 677C->T polymorphism and venous thrombosis: Results from the MEGA study
    • Bezemer I.D., Doggen C.J., Vos H.L., and Rosendaal F.R. No association between the common MTHFR 677C->T polymorphism and venous thrombosis: Results from the MEGA study. Arch Intern Med 167 (2007) 497-501
    • (2007) Arch Intern Med , vol.167 , pp. 497-501
    • Bezemer, I.D.1    Doggen, C.J.2    Vos, H.L.3    Rosendaal, F.R.4
  • 30
    • 33845964945 scopus 로고    scopus 로고
    • Homocysteine lowering by B vitamins and the secondary prevention of deep vein thrombosis and pulmonary embolism: A randomized, placebo-controlled, double-blind trial
    • den Heijer M., Willems H.P., Blom H.J., et al. Homocysteine lowering by B vitamins and the secondary prevention of deep vein thrombosis and pulmonary embolism: A randomized, placebo-controlled, double-blind trial. Blood 109 (2007) 139-144
    • (2007) Blood , vol.109 , pp. 139-144
    • den Heijer, M.1    Willems, H.P.2    Blom, H.J.3
  • 31
    • 4644258310 scopus 로고    scopus 로고
    • Use of antithrombotic agents during pregnancy: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
    • Bates S.M., Greer I.A., Hirsh J., and Ginsberg J.S. Use of antithrombotic agents during pregnancy: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 126 Suppl 3 (2004) 627S-644S
    • (2004) Chest , vol.126 , Issue.SUPPL. 3
    • Bates, S.M.1    Greer, I.A.2    Hirsh, J.3    Ginsberg, J.S.4
  • 32
    • 0024496352 scopus 로고
    • Recurrent thromboembolism in pregnancy and puerperium. Is there a need for thromboprophylaxis?
    • Tengborn L., Bergqvist D., Mätzsch T., Bergqvist A., and Hedner U. Recurrent thromboembolism in pregnancy and puerperium. Is there a need for thromboprophylaxis?. Am J Obstet Gynecol 160 (1989) 90-94
    • (1989) Am J Obstet Gynecol , vol.160 , pp. 90-94
    • Tengborn, L.1    Bergqvist, D.2    Mätzsch, T.3    Bergqvist, A.4    Hedner, U.5
  • 33
    • 0015951504 scopus 로고
    • Recurrence of venous thromboembolic disease and use of oral contraceptives
    • Badaracco M.A., and Vessey M.P. Recurrence of venous thromboembolic disease and use of oral contraceptives. Br Med J 1 (1974) 215-217
    • (1974) Br Med J , vol.1 , pp. 215-217
    • Badaracco, M.A.1    Vessey, M.P.2
  • 34
    • 0021051949 scopus 로고
    • The risks of antenatal subcutaneous heparin prophylaxis: A controlled trial
    • Howell R., Fidler J., Letsky E., and de Swiet M. The risks of antenatal subcutaneous heparin prophylaxis: A controlled trial. Br J Obstet Gynaecol 90 (1983) 1124-1128
    • (1983) Br J Obstet Gynaecol , vol.90 , pp. 1124-1128
    • Howell, R.1    Fidler, J.2    Letsky, E.3    de Swiet, M.4
  • 36
    • 0023404139 scopus 로고
    • Low risk of recurrent thromboembolism in pregnancy
    • de Swiet M., Floyd E., and Letsky E. Low risk of recurrent thromboembolism in pregnancy. Br J Hosp Med 38 (1987) 264
    • (1987) Br J Hosp Med , vol.38 , pp. 264
    • de Swiet, M.1    Floyd, E.2    Letsky, E.3
  • 37
    • 0034676551 scopus 로고    scopus 로고
    • Safety of withholding heparin in pregnant women with a history of venous thromboembolism. Recurrence of Clot in This Pregnancy Study Group
    • Brill-Edwards P., Ginsberg J.S., Gent M., et al. Safety of withholding heparin in pregnant women with a history of venous thromboembolism. Recurrence of Clot in This Pregnancy Study Group. N Engl J Med 343 (2000) 1439-1444
    • (2000) N Engl J Med , vol.343 , pp. 1439-1444
    • Brill-Edwards, P.1    Ginsberg, J.S.2    Gent, M.3
  • 38
    • 0034775825 scopus 로고    scopus 로고
    • ACOG practice bulletin. Thrombembolism in pregnancy
    • Barbour L.A. ACOG practice bulletin. Thrombembolism in pregnancy. Int J Gynaecol Obstet 75 (2001) 203-212
    • (2001) Int J Gynaecol Obstet , vol.75 , pp. 203-212
    • Barbour, L.A.1
  • 39
    • 0030317948 scopus 로고    scopus 로고
    • The long-term clinical course of acute deep venous thrombosis
    • Prandoni P., Lensing A.W., Cogo A., et al. The long-term clinical course of acute deep venous thrombosis. Ann Intern Med 125 (1996) 1-7
    • (1996) Ann Intern Med , vol.125 , pp. 1-7
    • Prandoni, P.1    Lensing, A.W.2    Cogo, A.3
  • 40
    • 0343674485 scopus 로고    scopus 로고
    • Predictors of recurrence after deep vein thrombosis and pulmonary embolism: A population-based cohort study
    • Heit J.A., Mohr D.N., Silverstein M.D., Petterson T.M., O'Fallon W.M., and Melton III L.J. Predictors of recurrence after deep vein thrombosis and pulmonary embolism: A population-based cohort study. Arch Intern Med 160 (2000) 761-768
    • (2000) Arch Intern Med , vol.160 , pp. 761-768
    • Heit, J.A.1    Mohr, D.N.2    Silverstein, M.D.3    Petterson, T.M.4    O'Fallon, W.M.5    Melton III, L.J.6
  • 41
    • 0029021115 scopus 로고
    • A comparison of six weeks with six months of oral anticoagulant therapy after a first episode of venous thromboembolism. Duration of Anticoagulation Trial Study Group
    • Schulman S., Rhedin A.S., Lindmarker P., et al. A comparison of six weeks with six months of oral anticoagulant therapy after a first episode of venous thromboembolism. Duration of Anticoagulation Trial Study Group. N Engl J Med 332 (1995) 1661-1665
    • (1995) N Engl J Med , vol.332 , pp. 1661-1665
    • Schulman, S.1    Rhedin, A.S.2    Lindmarker, P.3
  • 42
    • 0026646402 scopus 로고
    • Optimum duration of anticoagulation for deep-vein thrombosis and pulmonary embolism. Research Committee of the British Thoracic Society
    • Optimum duration of anticoagulation for deep-vein thrombosis and pulmonary embolism. Research Committee of the British Thoracic Society. Lancet 340 (1992) 873-876
    • (1992) Lancet , vol.340 , pp. 873-876
  • 43
    • 0028910906 scopus 로고
    • Mutation in the gene coding for coagulation factor V and the risk of myocardial infarction, stroke, and venous thrombosis in apparently healthy men
    • Ridker P.M., Hennekens C.H., Lindpaintner K., Stampfer M.J., Eisenberg P.R., and Miletich J.P. Mutation in the gene coding for coagulation factor V and the risk of myocardial infarction, stroke, and venous thrombosis in apparently healthy men. N Engl J Med 332 (1995) 912-917
    • (1995) N Engl J Med , vol.332 , pp. 912-917
    • Ridker, P.M.1    Hennekens, C.H.2    Lindpaintner, K.3    Stampfer, M.J.4    Eisenberg, P.R.5    Miletich, J.P.6
  • 44
    • 0034670050 scopus 로고    scopus 로고
    • Risk for subsequent venous thromboembolic complications in carriers of the prothrombin or the factor V gene mutation with a first episode of deep-vein thrombosis
    • Simioni P., Prandoni P., Lensing A.W., et al. Risk for subsequent venous thromboembolic complications in carriers of the prothrombin or the factor V gene mutation with a first episode of deep-vein thrombosis. Blood 96 (2000) 3329-3333
    • (2000) Blood , vol.96 , pp. 3329-3333
    • Simioni, P.1    Prandoni, P.2    Lensing, A.W.3
  • 45
    • 0031056991 scopus 로고    scopus 로고
    • The risk of recurrent venous thromboembolism in patients with an Arg506->Gln mutation in the gene for factor V (factor V Leiden)
    • Simioni P., Prandoni P., Lensing A.W., et al. The risk of recurrent venous thromboembolism in patients with an Arg506->Gln mutation in the gene for factor V (factor V Leiden). N Engl J Med 336 (1997) 399-403
    • (1997) N Engl J Med , vol.336 , pp. 399-403
    • Simioni, P.1    Prandoni, P.2    Lensing, A.W.3
  • 46
    • 0035165383 scopus 로고    scopus 로고
    • G20210A mutation in the prothrombin gene and the risk of recurrent venous thromboembolism
    • Miles J.S., Miletich J.P., Goldhaber S.Z., Hennekens C.H., and Ridker P.M. G20210A mutation in the prothrombin gene and the risk of recurrent venous thromboembolism. J Am Coll Cardiol 37 (2001) 215-218
    • (2001) J Am Coll Cardiol , vol.37 , pp. 215-218
    • Miles, J.S.1    Miletich, J.P.2    Goldhaber, S.Z.3    Hennekens, C.H.4    Ridker, P.M.5
  • 47
    • 0032892886 scopus 로고    scopus 로고
    • The risk of early recurrent venous thromboembolism after oral anticoagulant therapy in patients with the G20210A transition in the prothrombin gene
    • Eichinger S., Minar E., Hirschl M., et al. The risk of early recurrent venous thromboembolism after oral anticoagulant therapy in patients with the G20210A transition in the prothrombin gene. Thromb Haemost 81 (1999) 14-17
    • (1999) Thromb Haemost , vol.81 , pp. 14-17
    • Eichinger, S.1    Minar, E.2    Hirschl, M.3
  • 48
    • 20244369707 scopus 로고    scopus 로고
    • The risk of recurrent venous thromboembolism in patients with and without factor V Leiden
    • Eichinger S., Pabinger I., Stümpflen A., et al. The risk of recurrent venous thromboembolism in patients with and without factor V Leiden. Thromb Haemost 77 (1997) 624-628
    • (1997) Thromb Haemost , vol.77 , pp. 624-628
    • Eichinger, S.1    Pabinger, I.2    Stümpflen, A.3
  • 49
    • 0033539096 scopus 로고    scopus 로고
    • The risk of recurrent deep venous thrombosis among heterozygous carriers of both factor V Leiden and the G20210A prothrombin mutation
    • De Stefano V., Martinelli I., Mannucci P.M., et al. The risk of recurrent deep venous thrombosis among heterozygous carriers of both factor V Leiden and the G20210A prothrombin mutation. N Engl J Med 341 (1999) 801-806
    • (1999) N Engl J Med , vol.341 , pp. 801-806
    • De Stefano, V.1    Martinelli, I.2    Mannucci, P.M.3
  • 50
    • 0032954926 scopus 로고    scopus 로고
    • The risk of recurrent venous thromboembolism in carriers and non-carriers of the G1691A allele in the coagulation factor V gene and the G20210A allele in the prothrombin gene. DURAC Trial Study Group. Duration of Anticoagulation
    • Lindmarker P., Schulman S., Sten-Linder M., Wiman B., Egberg N., and Johnsson H. The risk of recurrent venous thromboembolism in carriers and non-carriers of the G1691A allele in the coagulation factor V gene and the G20210A allele in the prothrombin gene. DURAC Trial Study Group. Duration of Anticoagulation. Thromb Haemost 81 (1999) 684-689
    • (1999) Thromb Haemost , vol.81 , pp. 684-689
    • Lindmarker, P.1    Schulman, S.2    Sten-Linder, M.3    Wiman, B.4    Egberg, N.5    Johnsson, H.6
  • 51
    • 0033602514 scopus 로고    scopus 로고
    • A comparison of three months of anticoagulation with extended anticoagulation for a first episode of idiopathic venous thromboembolism
    • Kearon C., Gent M., Hirsh J., et al. A comparison of three months of anticoagulation with extended anticoagulation for a first episode of idiopathic venous thromboembolism. N Engl J Med 340 (1999) 901-907
    • (1999) N Engl J Med , vol.340 , pp. 901-907
    • Kearon, C.1    Gent, M.2    Hirsh, J.3
  • 52
    • 0032729187 scopus 로고    scopus 로고
    • Coexistence of factor V Leiden and Factor II A20210 mutations and recurrent venous thromboembolism
    • Margaglione M., D'Andrea G., Colaizzo D., et al. Coexistence of factor V Leiden and Factor II A20210 mutations and recurrent venous thromboembolism. Thromb Haemost 82 (1999) 1583-1587
    • (1999) Thromb Haemost , vol.82 , pp. 1583-1587
    • Margaglione, M.1    D'Andrea, G.2    Colaizzo, D.3
  • 53
    • 0034994092 scopus 로고    scopus 로고
    • The risk of recurrent venous thromboembolism among heterozygous carriers of the G20210A prothrombin gene mutation
    • De Stefano V., Martinelli I., Mannucci P.M., et al. The risk of recurrent venous thromboembolism among heterozygous carriers of the G20210A prothrombin gene mutation. Br J Haematol 113 (2001) 630-635
    • (2001) Br J Haematol , vol.113 , pp. 630-635
    • De Stefano, V.1    Martinelli, I.2    Mannucci, P.M.3
  • 54
    • 33645729527 scopus 로고    scopus 로고
    • Risk of recurrent venous thromboembolism in patients with common thrombophilia: A systematic review
    • Ho W.K., Hankey G.J., Quinlan D.J., and Eikelboom J.W. Risk of recurrent venous thromboembolism in patients with common thrombophilia: A systematic review. Arch Intern Med 166 (2006) 729-736
    • (2006) Arch Intern Med , vol.166 , pp. 729-736
    • Ho, W.K.1    Hankey, G.J.2    Quinlan, D.J.3    Eikelboom, J.W.4
  • 55
    • 4644221063 scopus 로고    scopus 로고
    • Antithrombotic therapy for venous thromboembolic disease: the Seventh ACCP Conference on antithrombotic and thrombolytic therapy
    • Buller H.R., Agnelli A., Hull R.D., et al. Antithrombotic therapy for venous thromboembolic disease: the Seventh ACCP Conference on antithrombotic and thrombolytic therapy. Chest 126 Suppl 3 (2004) 401S-428S
    • (2004) Chest , vol.126 , Issue.SUPPL. 3
    • Buller, H.R.1    Agnelli, A.2    Hull, R.D.3
  • 56
    • 4544290175 scopus 로고    scopus 로고
    • Long term management of patients after venous thromboembolism
    • Kearon C. Long term management of patients after venous thromboembolism. Circulation 110 Suppl 1 (2004) 10-18
    • (2004) Circulation , vol.110 , Issue.SUPPL. 1 , pp. 10-18
    • Kearon, C.1
  • 57
    • 23344449367 scopus 로고    scopus 로고
    • Duration of anticoagulation following VTE: A meta-analysis
    • Ost D., Tepper J., Mihara H., et al. Duration of anticoagulation following VTE: A meta-analysis. JAMA 294 (2005) 706
    • (2005) JAMA , vol.294 , pp. 706
    • Ost, D.1    Tepper, J.2    Mihara, H.3
  • 58
    • 0030608645 scopus 로고    scopus 로고
    • Co-inheritance of the 20210A allele of the prothrombin gene increases the risk of thrombosis in subjects with familial thrombophilia
    • Makris M., Preston F.E., Beauchamp N.J., et al. Co-inheritance of the 20210A allele of the prothrombin gene increases the risk of thrombosis in subjects with familial thrombophilia. Thromb Haemost 78 (1997) 1426-1429
    • (1997) Thromb Haemost , vol.78 , pp. 1426-1429
    • Makris, M.1    Preston, F.E.2    Beauchamp, N.J.3
  • 59
    • 0030793389 scopus 로고    scopus 로고
    • Familial thrombophilia: A complex genetic disorder
    • Koeleman B.P., Reitsma P.H., and Bertina R.M. Familial thrombophilia: A complex genetic disorder. Semin Hematol 34 (1997) 256-264
    • (1997) Semin Hematol , vol.34 , pp. 256-264
    • Koeleman, B.P.1    Reitsma, P.H.2    Bertina, R.M.3
  • 60
    • 0036190724 scopus 로고    scopus 로고
    • The incidence of recurrent venous thromboembolism in carriers of factor V Leiden is related to concomitant thrombophilic disorders
    • Meinardi J.R., Middeldorp S., de Kam P.J., et al. The incidence of recurrent venous thromboembolism in carriers of factor V Leiden is related to concomitant thrombophilic disorders. Br J Haematol 116 (2002) 625-631
    • (2002) Br J Haematol , vol.116 , pp. 625-631
    • Meinardi, J.R.1    Middeldorp, S.2    de Kam, P.J.3
  • 61
    • 0032501685 scopus 로고    scopus 로고
    • Decision analysis model of prolonged oral anticoagulant treatment in factor V Leiden carriers with first episode of deep vein thrombosis
    • Sarasin F.P., and Bounameaux H. Decision analysis model of prolonged oral anticoagulant treatment in factor V Leiden carriers with first episode of deep vein thrombosis. Br Med J 316 (1998) 95-99
    • (1998) Br Med J , vol.316 , pp. 95-99
    • Sarasin, F.P.1    Bounameaux, H.2
  • 62
    • 33845369571 scopus 로고    scopus 로고
    • Incidence of venous thromboembolism in first-degree relatives of patients with venous thromboembolism who have factor V Leiden
    • Couturaud F., Kearon C., Leroyer C., et al. Incidence of venous thromboembolism in first-degree relatives of patients with venous thromboembolism who have factor V Leiden. Thromb Haemost 96 (2006) 744-749
    • (2006) Thromb Haemost , vol.96 , pp. 744-749
    • Couturaud, F.1    Kearon, C.2    Leroyer, C.3
  • 63
    • 33750626078 scopus 로고    scopus 로고
    • A prospective cohort study on the absolute incidence of venous thromboembolism and arterial cardiovascular disease in asymptomatic carriers of the prothrombin 20210A mutation
    • Coppens M., van de Poel M.H., Bank I., et al. A prospective cohort study on the absolute incidence of venous thromboembolism and arterial cardiovascular disease in asymptomatic carriers of the prothrombin 20210A mutation. Blood 108 (2006) 2604-2607
    • (2006) Blood , vol.108 , pp. 2604-2607
    • Coppens, M.1    van de Poel, M.H.2    Bank, I.3
  • 64
    • 0037623698 scopus 로고    scopus 로고
    • Risk of venous thromboembolism in relatives of symptomatic probands with thrombophilia: A systematic review
    • Langlois N.J., and Wells P.S. Risk of venous thromboembolism in relatives of symptomatic probands with thrombophilia: A systematic review. Thromb Haemost 90 (2003) 17-26
    • (2003) Thromb Haemost , vol.90 , pp. 17-26
    • Langlois, N.J.1    Wells, P.S.2
  • 65
    • 0033485887 scopus 로고    scopus 로고
    • The incidence of venous thromboembolism in asymptomatic carriers of a deficiency of antithrombin, protein C, or protein S: A prospective cohort study
    • Sanson B., Simioni P., Tormene D., et al. The incidence of venous thromboembolism in asymptomatic carriers of a deficiency of antithrombin, protein C, or protein S: A prospective cohort study. Blood 94 (1999) 3702-3706
    • (1999) Blood , vol.94 , pp. 3702-3706
    • Sanson, B.1    Simioni, P.2    Tormene, D.3
  • 66
    • 0037980187 scopus 로고    scopus 로고
    • Inherited thrombophilia and gestational venous thromboembolism
    • Zotz R., Gerhardt A., and Sharf R. Inherited thrombophilia and gestational venous thromboembolism. Best Prac Res Clin Haematol 16 (2003) 243-259
    • (2003) Best Prac Res Clin Haematol , vol.16 , pp. 243-259
    • Zotz, R.1    Gerhardt, A.2    Sharf, R.3
  • 67
    • 33750352382 scopus 로고    scopus 로고
    • Inherited thrombophilia and venous thromboembolism
    • Simoni P., Tormene D., Spiezia L., et al. Inherited thrombophilia and venous thromboembolism. Sem Thromb Hemost 32 (2006) 700-708
    • (2006) Sem Thromb Hemost , vol.32 , pp. 700-708
    • Simoni, P.1    Tormene, D.2    Spiezia, L.3


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