메뉴 건너뛰기




Volumn 42, Issue 10, 2008, Pages 1429-1438

Posaconazole: An oral triazole with an extended spectrum of activity

Author keywords

Antifungal; Azole; Noxafil; Posaconazole; SCH 56592

Indexed keywords

AMPHOTERICIN B LIPID COMPLEX; ANIDULAFUNGIN; ASTEMIZOLE; CALCIUM CHANNEL BLOCKING AGENT; CASPOFUNGIN; CIMETIDINE; CISAPRIDE; CYCLOSPORIN; ERGOT ALKALOID; FLUCONAZOLE; HALOFANTRINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ITRACONAZOLE; MICAFUNGIN; PHENYTOIN; PIMOZIDE; POSACONAZOLE; QUINIDINE; RAPAMYCIN; RIFABUTIN; TACROLIMUS; TERFENADINE; VINBLASTINE; VINCRISTINE; VORICONAZOLE;

EID: 52949140624     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1L005     Document Type: Review
Times cited : (48)

References (67)
  • 1
    • 52949139373 scopus 로고    scopus 로고
    • Product information. Noxafil (posaconazole). Kenilworth, NJ: Schering Corporation, October 2006.
    • Product information. Noxafil (posaconazole). Kenilworth, NJ: Schering Corporation, October 2006.
  • 2
    • 23744481877 scopus 로고    scopus 로고
    • discussion 68-9
    • Keating GM. Posaconazole. Drugs 2005;65:1553-67; discussion 68-9.
    • (2005) Drugs , vol.65 , pp. 1553-1567
    • Posaconazole, K.G.M.1
  • 4
    • 34250658360 scopus 로고    scopus 로고
    • Posaconazole: A new broad-spectrum antifungal agent
    • Kwon DS, Mylonakis E. Posaconazole: a new broad-spectrum antifungal agent. Expert Opin Pharmacother 2007;8:1167-78.
    • (2007) Expert Opin Pharmacother , vol.8 , pp. 1167-1178
    • Kwon, D.S.1    Mylonakis, E.2
  • 5
    • 52949102035 scopus 로고    scopus 로고
    • Reference method for broth dilution antifungal susceptibility testing of yeasts; approved standard, second edition. NCCLS document M27-A2 [ISBN 1-56238-469-4, National Committee for Clinical Laboratory Standards, Wayne, PA, 2002
    • Reference method for broth dilution antifungal susceptibility testing of yeasts; approved standard - second edition. NCCLS document M27-A2 [ISBN 1-56238-469-4]. National Committee for Clinical Laboratory Standards, Wayne, PA, 2002.
  • 6
    • 0034806952 scopus 로고    scopus 로고
    • In vitro activities of posaconazole (Sch 56592) compared with those of itraconazole and fluconazole against 3,685 clinical isolates of Candida spp. and Cryptococcus neoformans
    • Pfaller MA, Messer SA, Hollis RJ, Jones RN. In vitro activities of posaconazole (Sch 56592) compared with those of itraconazole and fluconazole against 3,685 clinical isolates of Candida spp. and Cryptococcus neoformans. Antimicrob Agents Chemother 2001;45:2862-4.
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 2862-2864
    • Pfaller, M.A.1    Messer, S.A.2    Hollis, R.J.3    Jones, R.N.4
  • 7
    • 18544384549 scopus 로고    scopus 로고
    • Global trends in the antifungal susceptibility of Cryptococcus neoformans (1990 to 2004)
    • Pfaller MA, Messer SA, Boyken L, et al. Global trends in the antifungal susceptibility of Cryptococcus neoformans (1990 to 2004). J Clin Microbiol 2005;43:2163-7.
    • (2005) J Clin Microbiol , vol.43 , pp. 2163-2167
    • Pfaller, M.A.1    Messer, S.A.2    Boyken, L.3
  • 8
    • 0043025344 scopus 로고    scopus 로고
    • Activities of caspofungin, itraconazole, posaconazole, ravuconazole, voriconazole, and amphotericin B against 448 recent clinical isolates of filamentous fungi
    • Diekema DJ, Messer SA, Hollis RJ, Jones RN, Pfaller MA. Activities of caspofungin, itraconazole, posaconazole, ravuconazole, voriconazole, and amphotericin B against 448 recent clinical isolates of filamentous fungi. J Clin Microbiol 2003;41:3623-6.
    • (2003) J Clin Microbiol , vol.41 , pp. 3623-3626
    • Diekema, D.J.1    Messer, S.A.2    Hollis, R.J.3    Jones, R.N.4    Pfaller, M.A.5
  • 9
    • 0031689491 scopus 로고    scopus 로고
    • Comparison of in vitro activities of the new triazole SCH56592 and the echinocandins MK-0991 (L-743,872) and LY303366 against opportunistic filamentous and dimorphic fungi and yeasts
    • Espinel-Ingroff A. Comparison of in vitro activities of the new triazole SCH56592 and the echinocandins MK-0991 (L-743,872) and LY303366 against opportunistic filamentous and dimorphic fungi and yeasts. J Clin Microbiol 1998;36:2950-6.
    • (1998) J Clin Microbiol , vol.36 , pp. 2950-2956
    • Espinel-Ingroff, A.1
  • 10
    • 34548222507 scopus 로고    scopus 로고
    • Safety, tolerance, and efficacy of posaconazole therapy in patients with nonmeningeal disseminated or chronic pulmonary coccidioidomycosis
    • Catanzaro A, Cloud GA, Stevens DA, et al. Safety, tolerance, and efficacy of posaconazole therapy in patients with nonmeningeal disseminated or chronic pulmonary coccidioidomycosis. Clin Infect Dis 2007;45:562-8.
    • (2007) Clin Infect Dis , vol.45 , pp. 562-568
    • Catanzaro, A.1    Cloud, G.A.2    Stevens, D.A.3
  • 11
    • 39349086422 scopus 로고    scopus 로고
    • Resistance to antifungal agents: Mechanisms and clinical impact
    • Kanafani ZA, Perfect JR. Resistance to antifungal agents: mechanisms and clinical impact. Clin Infect Dis 2008;46:120-8.
    • (2008) Clin Infect Dis , vol.46 , pp. 120-128
    • Kanafani, Z.A.1    Perfect, J.R.2
  • 12
    • 0037310145 scopus 로고    scopus 로고
    • Mutations in Aspergillus fumigatus resulting in reduced susceptibility to posaconazole appear to be restricted to a single amino acid in the cytochrome P450 14alpha-demethylase
    • Mann PA, Parmegiani RM, Wei SQ, et al. Mutations in Aspergillus fumigatus resulting in reduced susceptibility to posaconazole appear to be restricted to a single amino acid in the cytochrome P450 14alpha-demethylase. Antimicrob Agents Chemother 2003;47:577-81.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 577-581
    • Mann, P.A.1    Parmegiani, R.M.2    Wei, S.Q.3
  • 13
    • 3042531281 scopus 로고    scopus 로고
    • Substitutions at methionine 220 in the 14alpha-sterol demethylase (Cyp51A) of Aspergillus fumigatus are responsible for resistance in vitro to azole antifungal drugs
    • Mellado E, Garcia-Effron G, Alcazar-Fuoli L, Cuenca-Estrella M, Rodriguez-Tudela JL. Substitutions at methionine 220 in the 14alpha-sterol demethylase (Cyp51A) of Aspergillus fumigatus are responsible for resistance in vitro to azole antifungal drugs. Antimicrob Agents Chemother 2004;48:2747-50.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 2747-2750
    • Mellado, E.1    Garcia-Effron, G.2    Alcazar-Fuoli, L.3    Cuenca-Estrella, M.4    Rodriguez-Tudela, J.L.5
  • 14
    • 33646823301 scopus 로고    scopus 로고
    • Control of a Candida glabrata prosthetic endovascular infection with posaconazole
    • Anstead GM, Martinez M, Graybill JR. Control of a Candida glabrata prosthetic endovascular infection with posaconazole. Med Mycol 2006;44:273-7.
    • (2006) Med Mycol , vol.44 , pp. 273-277
    • Anstead, G.M.1    Martinez, M.2    Graybill, J.R.3
  • 16
    • 34250731402 scopus 로고    scopus 로고
    • Safety and efficacy of posaconazole in the long-term treatment of azole-refractory oropharyngeal and esophageal candidiasis in patients with HIV infection
    • Vazquez JA, Skiest DJ, Tissot-Dupont H, Lennox JL, Boparai N, Isaacs R. Safety and efficacy of posaconazole in the long-term treatment of azole-refractory oropharyngeal and esophageal candidiasis in patients with HIV infection. HIV Clin Tri 2007;8:86-97.
    • (2007) HIV Clin Tri , vol.8 , pp. 86-97
    • Vazquez, J.A.1    Skiest, D.J.2    Tissot-Dupont, H.3    Lennox, J.L.4    Boparai, N.5    Isaacs, R.6
  • 17
    • 33846902613 scopus 로고    scopus 로고
    • Posaconazole for the treatment of azole-refractory oropharyngeal and esophageal candidiasis in subjects with HIV infection
    • Skiest DJ, Vazquez JA, Anstead GM, et al. Posaconazole for the treatment of azole-refractory oropharyngeal and esophageal candidiasis in subjects with HIV infection. Clin Infect Dis 2007;44:607-14.
    • (2007) Clin Infect Dis , vol.44 , pp. 607-614
    • Skiest, D.J.1    Vazquez, J.A.2    Anstead, G.M.3
  • 18
    • 9144274977 scopus 로고    scopus 로고
    • Changes in susceptibility to posaconazole in clinical isolates of Candida albicans
    • Li X, Brown N, Chau AS, et al. Changes in susceptibility to posaconazole in clinical isolates of Candida albicans. J Antimicrob Chemother 2004;53:74-80.
    • (2004) J Antimicrob Chemother , vol.53 , pp. 74-80
    • Li, X.1    Brown, N.2    Chau, A.S.3
  • 19
    • 0346784897 scopus 로고    scopus 로고
    • Three-dimensional models of wild-type and mutated forms of cytochrome P450 14alpha-sterol demethylases from Aspergillus fumigatus and Candida albicans provide insights into posaconazole binding
    • Xiao L, Madison V, Chau AS, Loebenberg D, Palermo RE, McNicholas PM. Three-dimensional models of wild-type and mutated forms of cytochrome P450 14alpha-sterol demethylases from Aspergillus fumigatus and Candida albicans provide insights into posaconazole binding. Antimicrob Agents Chemother 2004;48:568-74.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 568-574
    • Xiao, L.1    Madison, V.2    Chau, A.S.3    Loebenberg, D.4    Palermo, R.E.5    McNicholas, P.M.6
  • 20
    • 2542494102 scopus 로고    scopus 로고
    • Application of real-time quantitative PCR to molecular analysis of Candida albicans strains exhibiting reduced susceptibility to azoles
    • Chau AS, Mendrick CA, Sabatelli FJ, Loebenberg D, McNicholas PM. Application of real-time quantitative PCR to molecular analysis of Candida albicans strains exhibiting reduced susceptibility to azoles. Antimicrob Agents Chemother 2004;48:2124-31.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 2124-2131
    • Chau, A.S.1    Mendrick, C.A.2    Sabatelli, F.J.3    Loebenberg, D.4    McNicholas, P.M.5
  • 21
    • 0041422239 scopus 로고    scopus 로고
    • Pharmacokinetics, safety, and tolerability of oral posaconazole administered in single and multiple doses in healthy adults
    • Courtney R, Pai S, Laughlin M, Lim J, Batra V. Pharmacokinetics, safety, and tolerability of oral posaconazole administered in single and multiple doses in healthy adults. Antimicrob Agents Chemother 2003;47:2788-95.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 2788-2795
    • Courtney, R.1    Pai, S.2    Laughlin, M.3    Lim, J.4    Batra, V.5
  • 22
    • 33744498620 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of oral posaconazole in neutropenic stem cell transplant recipients
    • Gubbins PO, Krishna G, Sansone-Parsons A, et al. Pharmacokinetics and safety of oral posaconazole in neutropenic stem cell transplant recipients. Antimicrob Agents Chemother 2006;50:1993-9.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 1993-1999
    • Gubbins, P.O.1    Krishna, G.2    Sansone-Parsons, A.3
  • 23
    • 13244268757 scopus 로고    scopus 로고
    • Oral bioavailability of posaconazole in fasted healthy subjects: Comparison between three regimens and basis for clinical dosage recommendations
    • Ezzet F, Wexler D, Courtney R, Krishna G, Lim J, Laughlin M. Oral bioavailability of posaconazole in fasted healthy subjects: comparison between three regimens and basis for clinical dosage recommendations. Clin Pharmacokinet 2005;44:211-20.
    • (2005) Clin Pharmacokinet , vol.44 , pp. 211-220
    • Ezzet, F.1    Wexler, D.2    Courtney, R.3    Krishna, G.4    Lim, J.5    Laughlin, M.6
  • 24
    • 31944443967 scopus 로고    scopus 로고
    • Pharmacokinetics, safety, and efficacy of posaconazole in patients with persistent febrile neutropenia or refractory invasive fungal infection
    • Ullmann AJ, Comely OA, Burchardt A, et al. Pharmacokinetics, safety, and efficacy of posaconazole in patients with persistent febrile neutropenia or refractory invasive fungal infection. Antimicrob Agents Chemother 2006;50:658-66.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 658-666
    • Ullmann, A.J.1    Comely, O.A.2    Burchardt, A.3
  • 25
    • 1242351713 scopus 로고    scopus 로고
    • Effect of food on the relative bioavailability of two oral formulations of posaconazole in healthy adults
    • Courtney R, Wexler D, Radwanski E, Lim J, Laughlin M. Effect of food on the relative bioavailability of two oral formulations of posaconazole in healthy adults. Br J Clin Pharmacol 2004;57:218-22.
    • (2004) Br J Clin Pharmacol , vol.57 , pp. 218-222
    • Courtney, R.1    Wexler, D.2    Radwanski, E.3    Lim, J.4    Laughlin, M.5
  • 26
    • 1442349141 scopus 로고    scopus 로고
    • Pharmacokinetics of posaconazole coadministered with antacid in fasting or nonfasting healthy men
    • Courtney R, Radwanski E, Lim J, Laughlin M. Pharmacokinetics of posaconazole coadministered with antacid in fasting or nonfasting healthy men. Antimicrob Agents Chemother 2004;48:804-8.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 804-808
    • Courtney, R.1    Radwanski, E.2    Lim, J.3    Laughlin, M.4
  • 27
    • 16844387466 scopus 로고    scopus 로고
    • Posaconazole pharmacokinetics, safety, and tolerability in subjects with varying degrees of chronic renal disease
    • Courtney R, Sansone A, Smith W, et al. Posaconazole pharmacokinetics, safety, and tolerability in subjects with varying degrees of chronic renal disease. J Clin Pharmacol 2005;45:185-92.
    • (2005) J Clin Pharmacol , vol.45 , pp. 185-192
    • Courtney, R.1    Sansone, A.2    Smith, W.3
  • 28
    • 36849064207 scopus 로고    scopus 로고
    • Pharmacokinetics of oral posaconazole in allogeneic hematopoietic stem cell transplant recipients with graft-versus-host disease
    • Krishna G, Martinho M, Chandrasekar P, Ullmann AJ, Patino H. Pharmacokinetics of oral posaconazole in allogeneic hematopoietic stem cell transplant recipients with graft-versus-host disease. Pharmacotherapy 2007;27:1627-36.
    • (2007) Pharmacotherapy , vol.27 , pp. 1627-1636
    • Krishna, G.1    Martinho, M.2    Chandrasekar, P.3    Ullmann, A.J.4    Patino, H.5
  • 30
    • 33846561513 scopus 로고    scopus 로고
    • Effects of age, gender, and race/ethnicity on the pharmacokinetics of posaconazole in healthy volunteers
    • Sansone-Parsons A, Krishna G, Simon J, et al. Effects of age, gender, and race/ethnicity on the pharmacokinetics of posaconazole in healthy volunteers. Antimicrob Agents Chemother 2007;51:495-502.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 495-502
    • Sansone-Parsons, A.1    Krishna, G.2    Simon, J.3
  • 31
    • 52949106052 scopus 로고    scopus 로고
    • Clinical Pharmacology and Biopharmaceutics Review(s). Schering Corporation. New Drug Application No.: 022003. Center for Drug Evaluation and Research, 2006. www.fda.gov/cder/approval/index.htm (accessed 2007 Oct 25).
    • Clinical Pharmacology and Biopharmaceutics Review(s). Schering Corporation. New Drug Application No.: 022003. Center for Drug Evaluation and Research, 2006. www.fda.gov/cder/approval/index.htm (accessed 2007 Oct 25).
  • 33
    • 1842607473 scopus 로고    scopus 로고
    • Effect of posaconazole on cytochrome P450 enzymes: A randomized, open-label, two-way crossover study
    • Wexler D, Courtney R, Richards W, Banfield C, Lim J, Laughlin M. Effect of posaconazole on cytochrome P450 enzymes: a randomized, open-label, two-way crossover study. Eur J Pharm Sci 2004;21:645-53.
    • (2004) Eur J Pharm Sci , vol.21 , pp. 645-653
    • Wexler, D.1    Courtney, R.2    Richards, W.3    Banfield, C.4    Lim, J.5    Laughlin, M.6
  • 34
    • 33748557483 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of antifungals
    • Andes D. Pharmacokinetics and pharmacodynamics of antifungals. Infect Dis Clin North Am 2006;20:679-97.
    • (2006) Infect Dis Clin North Am , vol.20 , pp. 679-697
    • Andes, D.1
  • 35
    • 0347361711 scopus 로고    scopus 로고
    • Pharmacodynamics of a new triazole, posaconazole, in a murine model of disseminated candidiasis
    • Andes D, Marchillo K, Conklin R, et al. Pharmacodynamics of a new triazole, posaconazole, in a murine model of disseminated candidiasis. Antimicrob Agents Chemother 2004;48:137-42.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 137-142
    • Andes, D.1    Marchillo, K.2    Conklin, R.3
  • 36
    • 33846462456 scopus 로고    scopus 로고
    • Posaconazole vs. fluconazole or itraconazole prophylaxis in patients with neutropenia
    • Cornely OA, Maertens J, Winston DJ, et al. Posaconazole vs. fluconazole or itraconazole prophylaxis in patients with neutropenia. N Engl J Med 2007;356:348-59.
    • (2007) N Engl J Med , vol.356 , pp. 348-359
    • Cornely, O.A.1    Maertens, J.2    Winston, D.J.3
  • 37
    • 33846410666 scopus 로고    scopus 로고
    • Posaconazole or fluconazole for prophylaxis in severe graft-versus-host disease
    • Ullmann AJ, Lipton JH, Vesole DH, et al. Posaconazole or fluconazole for prophylaxis in severe graft-versus-host disease. N Engl J Med 2007;356:335-47.
    • (2007) N Engl J Med , vol.356 , pp. 335-347
    • Ullmann, A.J.1    Lipton, J.H.2    Vesole, D.H.3
  • 39
    • 33645782259 scopus 로고    scopus 로고
    • A multicenter randomized trial evaluating posaconazole versus fluconazole for the treatment of oropharyngeal candidiasis in subjects with HIV/AIDS
    • Vazquez JA, Skiest DJ, Nieto L, et al. A multicenter randomized trial evaluating posaconazole versus fluconazole for the treatment of oropharyngeal candidiasis in subjects with HIV/AIDS. Clin Infect Dis 2006;42:1179-86.
    • (2006) Clin Infect Dis , vol.42 , pp. 1179-1186
    • Vazquez, J.A.1    Skiest, D.J.2    Nieto, L.3
  • 40
    • 33845710284 scopus 로고    scopus 로고
    • Treatment of invasive aspergillosis with posaconazole in patients who are refractory to or intolerant of conventional therapy: An externally controlled trial
    • Walsh TJ, Raad I, Patterson TF, et al. Treatment of invasive aspergillosis with posaconazole in patients who are refractory to or intolerant of conventional therapy: an externally controlled trial. Clin Infect Dis 2007;44:2-12.
    • (2007) Clin Infect Dis , vol.44 , pp. 2-12
    • Walsh, T.J.1    Raad, I.2    Patterson, T.F.3
  • 41
    • 40849093036 scopus 로고    scopus 로고
    • Novel antifungal agents as salvage therapy for invasive aspergillosis in patients with hematologic malignancies: Posaconazole compared with high-dose lipid formulations of amphotericin B alone or in combination with caspofungin
    • Raad II, Hanna HA, Boktour M, et al. Novel antifungal agents as salvage therapy for invasive aspergillosis in patients with hematologic malignancies: posaconazole compared with high-dose lipid formulations of amphotericin B alone or in combination with caspofungin. Leukemia 2008;22:496-503.
    • (2008) Leukemia , vol.22 , pp. 496-503
    • Raad, I.I.1    Hanna, H.A.2    Boktour, M.3
  • 44
    • 34247628595 scopus 로고    scopus 로고
    • Posaconazole salvage therapy allows successful allogeneic hematopoietic stem cell transplantation in patients with refractory invasive mold infections
    • Mullane K, Toor AA, Kalnicky C, Rodriguez T, Klein J, Stiff P. Posaconazole salvage therapy allows successful allogeneic hematopoietic stem cell transplantation in patients with refractory invasive mold infections. Transplant Infect Dis 2007;9:89-96.
    • (2007) Transplant Infect Dis , vol.9 , pp. 89-96
    • Mullane, K.1    Toor, A.A.2    Kalnicky, C.3    Rodriguez, T.4    Klein, J.5    Stiff, P.6
  • 45
    • 33748549633 scopus 로고    scopus 로고
    • Salvage therapy of refractory chronic disseminated candidiasis in a patient with acute myeloid leukaemia and secondary prophylaxis during allogeneic stem cell transplantation
    • Vehreschild JJ, Kruger K, Kurzai O, et al. Salvage therapy of refractory chronic disseminated candidiasis in a patient with acute myeloid leukaemia and secondary prophylaxis during allogeneic stem cell transplantation. Mycoses 2006;49(suppl 1):42-7.
    • (2006) Mycoses , vol.49 , Issue.SUPPL. 1 , pp. 42-47
    • Vehreschild, J.J.1    Kruger, K.2    Kurzai, O.3
  • 46
    • 33644801460 scopus 로고    scopus 로고
    • Pulmonary mucormycosis (zygomycosis) in a lung transplant recipient: Recovery after posaconazole therapy
    • Brugiere O, Dauriat G, Mal H, et al. Pulmonary mucormycosis (zygomycosis) in a lung transplant recipient: recovery after posaconazole therapy. Transplantation 2005;80:1361-2.
    • (2005) Transplantation , vol.80 , pp. 1361-1362
    • Brugiere, O.1    Dauriat, G.2    Mal, H.3
  • 47
    • 34249716758 scopus 로고    scopus 로고
    • Successful treatment and limb salvage of mucor necrotizing fasciitis after kidney transplantation with posaconazole
    • Harada AS, Lau W. Successful treatment and limb salvage of mucor necrotizing fasciitis after kidney transplantation with posaconazole. Hawaii Med J 2007;66:68-71.
    • (2007) Hawaii Med J , vol.66 , pp. 68-71
    • Harada, A.S.1    Lau, W.2
  • 48
    • 1542723479 scopus 로고    scopus 로고
    • Aspergillus fumigatus empyema, arthritis, and calcaneal osteomyelitis in a lung transplant patient successfully treated with posaconazole
    • Lodge BA, Ashley ED, Steele MP, Perfect JR. Aspergillus fumigatus empyema, arthritis, and calcaneal osteomyelitis in a lung transplant patient successfully treated with posaconazole. J Clin Microbiol 2004;42:1376-8.
    • (2004) J Clin Microbiol , vol.42 , pp. 1376-1378
    • Lodge, B.A.1    Ashley, E.D.2    Steele, M.P.3    Perfect, J.R.4
  • 49
    • 0038468730 scopus 로고    scopus 로고
    • Mucormycosis (zygomycosis) in a heart-kidney transplant recipient: Recovery after posaconazole therapy
    • Tobon AM, Arango M, Fernandez D, Restrepo A. Mucormycosis (zygomycosis) in a heart-kidney transplant recipient: recovery after posaconazole therapy. Clin Infect Dis 2003;36:1488-91.
    • (2003) Clin Infect Dis , vol.36 , pp. 1488-1491
    • Tobon, A.M.1    Arango, M.2    Fernandez, D.3    Restrepo, A.4
  • 51
    • 27144459842 scopus 로고    scopus 로고
    • Activity of posaconazole in the treatment of central nervous system fungal infections
    • Pitisuttithum P, Negroni R, Graybill JR, et al. Activity of posaconazole in the treatment of central nervous system fungal infections. J Antimicrob Chemother 2005;56:745-55.
    • (2005) J Antimicrob Chemother , vol.56 , pp. 745-755
    • Pitisuttithum, P.1    Negroni, R.2    Graybill, J.R.3
  • 52
    • 27644563878 scopus 로고    scopus 로고
    • A case of disseminated histoplasmosis successfully treated with the investigational drug posaconazole
    • Clark B, Foster R, Tunbridge A, Green S. A case of disseminated histoplasmosis successfully treated with the investigational drug posaconazole. J Infect 2005;51:e177-80.
    • (2005) J Infect , vol.51
    • Clark, B.1    Foster, R.2    Tunbridge, A.3    Green, S.4
  • 53
    • 33947113790 scopus 로고    scopus 로고
    • Salvage treatment of histoplasmosis with posaconazole
    • Restrepo A, Tobon A, Clark B, et al. Salvage treatment of histoplasmosis with posaconazole. J Infect 2007;54:319-27.
    • (2007) J Infect , vol.54 , pp. 319-327
    • Restrepo, A.1    Tobon, A.2    Clark, B.3
  • 55
    • 35448949963 scopus 로고    scopus 로고
    • Posaconazole therapy for chronic refractory coccidioidomycosis
    • Stevens DA, Rendon A, Gaona-Flores V, et al. Posaconazole therapy for chronic refractory coccidioidomycosis. Chest 2007;132:952-8.
    • (2007) Chest , vol.132 , pp. 952-958
    • Stevens, D.A.1    Rendon, A.2    Gaona-Flores, V.3
  • 56
    • 33646445731 scopus 로고    scopus 로고
    • Posaconazole as salvage treatment for invasive fusariosis in patients with underlying hematologic malignancy and other conditions
    • Raad II, Hachem RY, Herbrecht R, et al. Posaconazole as salvage treatment for invasive fusariosis in patients with underlying hematologic malignancy and other conditions. Clin Infect Dis 2006;42:1398-403.
    • (2006) Clin Infect Dis , vol.42 , pp. 1398-1403
    • Raad, I.I.1    Hachem, R.Y.2    Herbrecht, R.3
  • 57
    • 34247617408 scopus 로고    scopus 로고
    • Successful treatment of disseminated fusariosis with posaconazole during neutropenia and subsequent allogeneic hematopoietic stem cell transplantation
    • Gupta S, Almyroudis NG, Battiwalla M, et al. Successful treatment of disseminated fusariosis with posaconazole during neutropenia and subsequent allogeneic hematopoietic stem cell transplantation. Transpl Infect Dis 2007;9:156-60.
    • (2007) Transpl Infect Dis , vol.9 , pp. 156-160
    • Gupta, S.1    Almyroudis, N.G.2    Battiwalla, M.3
  • 58
    • 52949104359 scopus 로고    scopus 로고
    • Schering-Plough. POS vs FLU for first line treatment of coccidioidomycosis (Study P04558). ClinicalTrials.gov Identifier: NCT00423267. www.clinicaltrials.gov/ct2/show/NCT00423267?term=posaconazole&rank=11 (accessed 2007 Dec 28).
    • Schering-Plough. POS vs FLU for first line treatment of coccidioidomycosis (Study P04558). ClinicalTrials.gov Identifier: NCT00423267. www.clinicaltrials.gov/ct2/show/NCT00423267?term=posaconazole&rank=11 (accessed 2007 Dec 28).
  • 59
    • 52949134050 scopus 로고    scopus 로고
    • Schering-Plough. A study to evaluate efficacy and safety of four posaconazole regimens with placebo and terbinafine in the treatment of toenail onychomycosis (Study P05082). ClinicalTrials.gov Identifier: NCT00491764.www.clinicaltrials.gov/ct2/show/NCT00491764?term= posaconazole&rank=9 (accessed 2007 Dec 28).
    • Schering-Plough. A study to evaluate efficacy and safety of four posaconazole regimens with placebo and terbinafine in the treatment of toenail onychomycosis (Study P05082). ClinicalTrials.gov Identifier: NCT00491764.www.clinicaltrials.gov/ct2/show/NCT00491764?term= posaconazole&rank=9 (accessed 2007 Dec 28).
  • 60
    • 0036027918 scopus 로고    scopus 로고
    • Simultaneous high-performance liquid chromatographic determination of SCH 59884 (phosphate ester prodrug of SCH 56592), SCH 207962 and SCH 56592 in dog plasma
    • Kim H, Kumari P, Lin CC, Nomeir AA. Simultaneous high-performance liquid chromatographic determination of SCH 59884 (phosphate ester prodrug of SCH 56592), SCH 207962 and SCH 56592 in dog plasma. J Pharm Biomed Anal 2002;27:295-303.
    • (2002) J Pharm Biomed Anal , vol.27 , pp. 295-303
    • Kim, H.1    Kumari, P.2    Lin, C.C.3    Nomeir, A.A.4
  • 61
    • 33744831964 scopus 로고    scopus 로고
    • Safety of long-term oral posaconazole use in the treatment of refractory invasive fungal infections
    • Raad II, Graybill JR, Bustamante AB, et al. Safety of long-term oral posaconazole use in the treatment of refractory invasive fungal infections. Clin Infect Dis 2006;42:1726-34.
    • (2006) Clin Infect Dis , vol.42 , pp. 1726-1734
    • Raad, I.I.1    Graybill, J.R.2    Bustamante, A.B.3
  • 63
    • 33845365814 scopus 로고    scopus 로고
    • Factors influencing the magnitude and clinical significance of drug interactions between azole antifungals and select immunosuppressants
    • Saad AH, DePestel DD, Carver PL. Factors influencing the magnitude and clinical significance of drug interactions between azole antifungals and select immunosuppressants. Pharmacotherapy 2006;26:1730-44.
    • (2006) Pharmacotherapy , vol.26 , pp. 1730-1744
    • Saad, A.H.1    DePestel, D.D.2    Carver, P.L.3
  • 64
    • 33947354866 scopus 로고    scopus 로고
    • Evaluation of the pharmacokinetics of posaconazole and rifabutin following co-administration to healthy men
    • Krishna G, Parsons A, Kantesaria B, Mant T. Evaluation of the pharmacokinetics of posaconazole and rifabutin following co-administration to healthy men. Curr Med Res Opin 2007;23:545-52.
    • (2007) Curr Med Res Opin , vol.23 , pp. 545-552
    • Krishna, G.1    Parsons, A.2    Kantesaria, B.3    Mant, T.4
  • 65
    • 34347211017 scopus 로고    scopus 로고
    • Drug interaction assessment following concomitant administration of posaconazole and phenytoin in healthy men
    • Krishna G, Sansone-Parsons A, Kantesaria B. Drug interaction assessment following concomitant administration of posaconazole and phenytoin in healthy men. Curr Med Res Opin 2007;23:1415-22.
    • (2007) Curr Med Res Opin , vol.23 , pp. 1415-1422
    • Krishna, G.1    Sansone-Parsons, A.2    Kantesaria, B.3
  • 66
    • 52949117658 scopus 로고    scopus 로고
    • Red book. 2007 ed. Montvale, NJ: Thomson Healthcare Inc., 2007.
    • Red book. 2007 ed. Montvale, NJ: Thomson Healthcare Inc., 2007.
  • 67
    • 33846439749 scopus 로고    scopus 로고
    • Prophylaxis and aspergillosis - has the principle been proven?
    • De Pauw BE, Donnelly JP. Prophylaxis and aspergillosis - has the principle been proven? N Engl J Med 2007;356:409-11.
    • (2007) N Engl J Med , vol.356 , pp. 409-411
    • De Pauw, B.E.1    Donnelly, J.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.