A Tripartite Complex Containing MRCK Modulates Lamellar Actomyosin Retrograde Flow

Cell

Volumn 135, Issue 1, 2008, Pages 123-136

  Tan, Ivan ^a   Yong, Jeffery ^a,b   Dong, Jing Ming ^a   Lim, Louis ^a,c   Leung, Thomas ^a,b  

^a INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

CELLBIO

Indexed keywords

ADAPTOR PROTEIN; ALPHA TUBULIN; MYOSIN ADENOSINE TRIPHOSPHATASE; MYOSIN II; PHOSPHOTRANSFERASE; PROTEIN CDC42; PROTEIN LRAP35A; PROTEIN MRCK; PROTEIN MYO18A; PROTEIN MYO2A; RAC PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL ADHESION; CELL MIGRATION; CELL MOTILITY; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LAMELLAR BODY; LAMELLIPODIUM; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; WILD TYPE;

EID: 52949140261     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2008.09.018     Document Type: Article

References (37)

1. Basu R., and Chang F. Shaping the actin cytoskeleton using microtubule tips. Curr. Opin. Cell Biol. 19 (2007) 88-94
2. Cai Y., Biais N., Giannone G., Tanase M., Jiang G., Hofman J.M., Wiggins C.H., Silberzan P., Buguin A., Ladoux B., et al. Nonmuscle myosin IIA-dependent force inhibits cell spreading and drives F-actin flow. Biophys. J. 91 (2006) 3907-3920
3. Chen X.Q., Tan I., Leung T., and Lim L. The myotonic dystrophy kinase-related Cdc42-binding kinase is involved in the regulation of neurite outgrowth in PC12 cells. J. Biol. Chem. 274 (1999) 19901-19905
4. Delorme V., Machacek M., DerMardirossian C., Anderson K.L., Wittmann T., Hanein D., Waterman-Storer C.M., Danuser G., and Bokoch G. Cofilin activity downstream of PAK1 regulates cell protrusion efficiency by organizing lamellipodium and lamella actin networks. Dev. Cell 13 (2007) 646-662
5. Even-Ram S., Doyle A.D., Conti M.A., Matsumoto K., Adelstein R.S., and Yamada K.M. Myosin IIA regulates cell motility and actomyosin-microtubule crosstalk. Nat. Cell Biol. 9 (2007) 299-309
6. Giannone G., Dubin-Thaler B.J., Döbereiner H., Kieffer N., Bresnick A.R., and Sheetz M.P. Periodic lamellipodial contractions correlate with rearward actin waves. Cell 116 (2004) 431-443
7. Gomes E.R., Jani S., and Gundersen G.G. Nuclear movement regulated by Cdc42, MRCK, myosin, and actin flow establishes MTOC polarization in migrating cells. Cell 121 (2005) 451-463
8. Groeger G., and Nobes C.D. Co-operative Cdc42 and Rho signalling mediates ephrinB-triggered endothelial cell retraction. Biochem. J. 404 (2007) 23-29
9. Gupton S.L., and Waterman-Storer C.M. Spatiotemporal feedback between actomyosin and focal-adhesion systems optimizes rapid cell migration. Cell 125 (2006) 1361-1374
10. Gupton S.L., Eisenmann K., Alberts A.S., and Waterman-Storer C.M. mDia2 regulates actin and focal adhesion dynamics and organization in the lamella for efficient epithelial cell migration. J. Cell Sci. 120 (2007) 3475-3487
11. Isogawa Y., Kon T., Inoue T., Ohkura R., Yamakawa H., Ohara O., and Sutoh K. The N-terminal domain of MYO18A has an ATP-insensitive actin-binding site. Biochemistry 44 (2005) 6190-6196
12. Kaibuchi K., Kuroda S., and Amano M. Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells. Annu. Rev. Biochem. 68 (1999) 459-486
13. Katoh K., Kano Y., Amano M., Onishi H., Kaibuchi K., and Fujiwara K. Rho-kinase-mediated contraction of isolated stress fibers. J. Cell Biol. 153 (2001) 569-584
14. Kinoshita M., Field C.M., Coughlin M.L., Straight A.F., and Mitchison T.J. Self- and actin-templated assembly of mammalian septins. Dev. Cell 3 (2002) 791-802
15. Kolega J. Asymmetric distribution of myosin IIB in migrating endothelial cells is regulated by a rho-dependent kinase and contributes to tail retraction. Mol. Biol. Cell 14 (2003) 4745-4757
16. Kolega J. The role of myosin II motor activity in distributing myosin asymmetrically and coupling protrusive activity to cell translocation. Mol. Biol. Cell 17 (2006) 4435-4445
17. Lauffenburger D.A., and Horwitz A.F. Cell migration: a physical integrated molecular process. Cell 84 (1996) 359-369
18. Leung T., Chen X.Q., Manser E., and Lim L. Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization. Mol. Cell. Biol. 18 (1998) 130-140
19. Longtine M.S., Theesfeld C.L., McMillan J.N., Weaver E., Pringle J.R., and Lew D.J. Septin-dependent assembly of a cell cycle-regulatory module in Saccharomyces cerevisiae. Mol. Cell. Biol. 20 (2000) 4049-4061
20. Mitchison T.J., and Cramer L.P. Actin-based cell motility and cell locomotion. Cell 84 (1996) 371-379
21. Mori K., Matsuda K., Furusawa T., Kawata M., Inoue T., and Obinata M. Subcellular localization and dynamics of MysPDZ (Myo18A) in live mammalian cells. Biochem. Biophys. Res. Commun. 326 (2005) 491-498
22. Nemethova M., Auinger S., and Small J.V. Building the actin cytoskeleton: filopodia contribute to the construction of contractile bundles in the lamella. J. Cell Biol. 180 (2008) 1233-1244
23. Ng Y., Tan I., Lim L., and Leung T. Expression of the human myotonic dystrophy kinase-related Cdc42-binding kinase gamma is regulated by promoter DNA methylation and Sp1 binding. J. Biol. Chem. 279 (2004) 34156-34164
24. Pertz O., Hodgson L., Klemke R.L., and Hahn K.M. Spatiotemporal dynamics of RhoA activity in migrating cells. Nature 440 (2006) 1069-1072
25. Pollard T.D., and Borisy G.G. Cell motility driven by assembly and disassembly of actin filaments. Cell 112 (2003) 453-465
26. Ponti A., Machacek M., Gupton S.L., Waterman-Storer C.M., and Danuser G. Two distinct actin networks drive the protrusion of migrating cells. Science 305 (2004) 1782-1785
27. Raftopoulou M., and Hall A. Cell migration: Rho GTPases lead the way. Dev. Biol. 265 (2004) 23-32
28. Songyang Z., Fanning A.S., Fu C., Xu J., Marfatia S.M., Chishti A.H., Crompton A., Chan A.C., Anderson J.M., and Cantley L.C. Recognition of unique carboxyl-terminal motifs by distinct PDZ domains. Science 275 (1997) 73-77
29. Straight A.F., Cheung A., Limouze J., Chen I., Westwood N.J., Sellers J.R., and Mitchison T.J. Dissecting temporal and spatial control of cytokinesis with a myosin II inhibitor. Science 299 (2003) 1743-1747
30. Sumi T., Matsumoto K., Shibuya A., and Nakamura T. Activation of LIM kinases by myotonic dystrophy kinase-related Cdc42-binding kinase alpha. J. Biol. Chem. 276 (2001) 23092-23096
31. Tan I., Seow K.T., Lim L., and Leung T. Intermolecular and intramolecular interactions regulate catalytic activity of myotonic dystrophy kinase-related Cdc42-binding kinase alpha. Mol. Cell. Biol. 21 (2001) 2767-2778
32. Totsukawa G., Wu Y., Sasaki Y., Hartshorne D.J., Yamakita Y., Yamashiro S., and Matsumura F. Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts. J. Cell Biol. 164 (2004) 427-439
33. Vicente-Manzanares M., Zareno J., Whitmore L., Choi C.K., and Horwitz A.F. Regulation of protrusion, adhesion dynamics, and polarity by myosins IIA and IIB in migrating cells. J. Cell Biol. 176 (2007) 573-580
34. Wilkinson S., Paterson H.F., and Marshall C.J. Cdc42-MRCK and Rho-ROCK signalling cooperate in myosin phosphorylation and cell invasion. Nat. Cell Biol. 7 (2005) 255-261
35. Yamana N., Aarakawa Y., Nishino T., Kurokawa K., Tanji M., Itoh R.E., Monypenny J., Ishizaki T., Bito H., Nozaki K., et al. The Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-Src. Mol. Cell. Biol. 26 (2006) 6844-6858
36. Yamashiro S., Totsukawa G., Yamakita Y., Sasaki Y., Madaule P., Ishizaki T., Narumiya S., and Matsumura F. Citron Kinase, a Rho-dependent kinase, induces di-phosphorylation of regulatory light chain of Myosin II. Mol. Biol. Cell 14 (2003) 1745-1756
37. Zhao Z.S., Manser E., Loo T.H., and Lim L. Coupling of PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassembly. Mol. Cell. Biol. 20 (2000) 6354-6363