Preventive Effect of Rolipram, a Phosphodiesterase 4 Enzyme Inhibitor, on Oxidative Renal Injury in Acute Ascending Pyelonephritis Model in Rats

Urology

Volumn 72, Issue 4, 2008, Pages 743-748

  Görür, Sadik ^a   Çelik, Sefa ^a   Hakverdi, Sibel ^a   Aslantaş, Özkan ^a   Erdoǧan, Suat ^a   Aydin, Muhsin ^a   Ocak, Sabahattin ^a   Namik Kiper, Ahmet ^a  

^a MUSTAFA KEMAL UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

CATALASE; MALONALDEHYDE; NITRIC OXIDE; PHOSPHODIESTERASE IV INHIBITOR; ROLIPRAM; SUPEROXIDE DISMUTASE;

ACUTE PYELONEPHRITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER; CONTROLLED STUDY; DEATH; DRUG EFFECT; DRUG SCREENING; ENTEROBACTER INFECTION; ENZYME ACTIVITY; ESCHERICHIA COLI; EXPERIMENTAL MODEL; EXPERIMENTAL RAT; HISTOPATHOLOGY; INFLAMMATION; INOCULATION; KIDNEY HOMOGENATE; KIDNEY INJURY; KIDNEY PARENCHYMA; MALE; NONHUMAN; OXIDATIVE RENAL INJURY; PRIORITY JOURNAL; RAT; URETHRA OBSTRUCTION;

ACUTE DISEASE; ANIMALS; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; DISEASE MODELS, ANIMAL; KIDNEY; MALE; OXIDATION-REDUCTION; PHOSPHODIESTERASE INHIBITORS; PYELONEPHRITIS; RATS; RATS, WISTAR; ROLIPRAM;

EID: 52949118486     PISSN: 00904295     EISSN: 15279995     Source Type: Journal    
DOI: 10.1016/j.urology.2008.04.013     Document Type: Article

References (28)

1. Sirin A., Emre S., Alpay H., et al. Etiology of chronic renal failure in Turkish children. Pediatr Nephrol. 9 (1995) 549-552
2. Matsumoto T., Mizunoe Y., Ogata N., et al. Role of superoxide in renal scarring following infection by mannose-sensitive piliated bacteria. Urol Res. 19 (1991) 229-233
3. Matsumoto T., Mitzunoe Y., Ogata N., et al. Antioxidant effect on renal scarring following infection of mannose-sensitive-piliated bacteria. Nephron. 60 (1992) 210-215
4. Celik S., Gorur S., Aslantas O., et al. Caffeic acid phenethyl ester suppresses oxidative stress in Escherichia coli-induced pyelonephritis in rats. Mol Cell Biochem. 297 (2007) 131-138
5. Glauser M.P., Meylan P., and Bille J. The inflammatory response and tissue damage. The example of renal scars following acute renal infection. Pediatr Nephrol. 1 (1987) 615-622
6. Biyikli N.K., Tugtepe H., Sener G., et al. Oxytocin alleviates oxidative renal injury in pyelonephritic rats via a neutrophil-dependent mechanism. Peptides 27 (2006) 2249-2257
7. Yagmurlu A., Boleken M.E., Ertoy D., et al. Preventive effect of pentoxifylline on renal scarring in rat model of pyelonephritis. Urology 61 (2003) 1037-1041
8. Haraoka M., Matsumoto T., Mizunoe Y., et al. Effect of prednisolone on renal scarring in rats following infection with Serratia marcescens. Ren Fail. 15 (1993) 567-571
9. Sanz M.J., Cortijo J., and Morcillo E.J. PDE4 inhibitors as new anti-inflammatory drugs: Effects on cell trafficking and cell adhesion molecules expression. Pharmacol Ther. 106 (2005) 269-297
10. Burnouf C., and Pruniaux M.P. Recent advances in PDE4 inhibitors as immunoregulators and anti-inflammatory drugs. Curr Pharm Des. 8 (2002) 1255-1296
11. Souness J.E., Aldous D., and Sargent C. Immunosuppressive and anti-inflammatory effects of cyclic AMP phosphodiesterase (PDE) type 4 inhibitors. J Immunopharmacol. 47 (2000) 127-162
12. Schütte H., Schell A., Schafer C., et al. Subthreshold doses of nebulized prostacyclin and rolipram synergistically protect against lung ischemia-reperfusion. Transplantation 75 (2003) 814-821
13. Kyoi T., Kitazawa S., Tajima K., et al. Phosphodiesterase type IV inhibitors prevent ischemia-reperfusion-induced gastric injury in rats. J Pharmacol Sci. 95 (2004) 321-328
14. Souza D.G., Cassali G.D., Poole S., et al. Effects of inhibition of PDE4 and TNF-alpha on local and remote injuries following ischemia and reperfusion injury. Br J Pharmacol. 134 (2001) 985-994
15. Chi Z.L., Hayasaka S., Zhang X.Y., et al. Effects of rolipram, a selective inhibitor of type 4 phosphodiesterase, on lipopolysaccharide-induced uveitis in rats. Invest Ophthalmol Vis Sci. 45 (2004) 2497-2502
16. Bennett R.T., Mazzaccaro R.J., Chopra N., et al. Suppression of renal inflammation with vitamins A and E in ascending pyelonephritis in rats. J Urol. 161 (1999) 1681-1684
17. Erdogan S., Celik S., Aslantas O., et al. Elevated cAMP levels reverse Brucella melitensis-induced lipid peroxidation and stimulate IL-10 transcription in rats. Res Vet Sci. 82 (2007) 181-186
18. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 72 (1976) 248-254
19. Cortas N.K., and Wakid N.W. Determination of inorganic nitrate in serum and urine by a kinetic cadmium-reduction method. Clin Chem. 36 (1990) 1440-1443
20. Yoshioka T., Kawada K., Shimada T., et al. Lipid peroxidation in maternal and cord blood and protective mechanism against activated-oxygen toxicity in the blood. Am J Obstet Gynecol. 135 (1979) 372-376
21. Sun Y., Oberley L.W., and Li Y. A simple method for clinical assay of superoxide dismutase. Clin Chem. 34 (1988) 497-500
22. Aebi Y. Catalase in vitro. Methods Enzymol. 105 (1984) 121-126
23. Turner T.T., Tung K.S., Tomomasa H., et al. Acute testicular ischemia results in germ cell-specific apoptosis in the rat. Biol Reprod. 57 (1997) 1267-1274
24. Kabore A.F., Simard M., and Bergeron M.G. Local production of inflammatory mediators in an experimental model of acute obstructive pyelonephritis. J Infect Dis. 179 (1999) 1162-1172
25. Bank N., Kiroycheva M., Singhal P.C., et al. Inhibition of nitric oxide synthase ameliorates cellular injury in sickle cell mouse kidneys. Kidney Int. 58 (2000) 82-89
26. Nowicki B., Singhal J., Fang L., et al. Inverse relationship between severity of experimental pyelonephritis and nitric oxide production in C3H/HeJ mice. Infect Immun. 67 (1999) 2421-2427
27. Prillaman H.M., and Turner T.T. Rescue of testicular function after acute experimental torsion. J Urol. 157 (1997) 340-345
28. Kaur A., Garg U.C., Sethi A.K., et al. Effect of various oxygen free radical scavengers in preventing tissue injury caused by Escherichia coli in pyelonephritic mice. Biochem Int. 16 (1988) 1083-1093