메뉴 건너뛰기




Volumn 46, Issue 1, 2008, Pages 106-115

HIV-1-Tat potentiates CXCL12/Stromal Cell-Derived Factor 1-induced downregulation of membrane CXCR4 in T lymphocytes through Protein kinase C zeta

Author keywords

CXCL12; CXCR4; HIV 1 tat; Protein kinase zeta; Receptor internalization; T lymphocytes

Indexed keywords

BETA ARRESTIN; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CXCR4; DOXYCYCLINE; G COUPLED RECEPTOR KINASE 2; G COUPLED RECEPTOR KINASE 6; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PROTEIN KINASE B; PROTEIN KINASE C ZETA; STROMAL CELL DERIVED FACTOR 1; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

EID: 52949117705     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2008.07.004     Document Type: Article
Times cited : (6)

References (66)
  • 1
    • 0026552626 scopus 로고
    • An 11-base-pair DNA sequence motif apparently unique to the human interleukin 4 gene confers responsiveness to T-cell activation signals
    • Abe E., De Waal Malefyt R., Matsuda I., Arai K., and Arai N. An 11-base-pair DNA sequence motif apparently unique to the human interleukin 4 gene confers responsiveness to T-cell activation signals. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 2864-2868
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 2864-2868
    • Abe, E.1    De Waal Malefyt, R.2    Matsuda, I.3    Arai, K.4    Arai, N.5
  • 3
    • 0030914237 scopus 로고    scopus 로고
    • HIV-1 Tat induces the expression of the interleukin-6 (IL6) gene by binding to the IL6 leader RNA and by interacting with CAAT enhancer-binding protein beta (NF-IL6) transcription factors
    • Ambrosino C., Ruocco M.R., Chen X., Mallardo M., Baudi F., Trematerra S., Quinto I., Venuta S., and Scala G. HIV-1 Tat induces the expression of the interleukin-6 (IL6) gene by binding to the IL6 leader RNA and by interacting with CAAT enhancer-binding protein beta (NF-IL6) transcription factors. J. Biol. Chem. 272 (1997) 14883-14892
    • (1997) J. Biol. Chem. , vol.272 , pp. 14883-14892
    • Ambrosino, C.1    Ruocco, M.R.2    Chen, X.3    Mallardo, M.4    Baudi, F.5    Trematerra, S.6    Quinto, I.7    Venuta, S.8    Scala, G.9
  • 4
    • 21644455702 scopus 로고    scopus 로고
    • Proliferative activity of extracellular HIV-1 Tat protein in human epithelial cells: expression profile of pathogenetically relevant genes
    • Bettaccini A.A., Baj A., Accolla R.S., Basolo F., and Toniolo A.Q. Proliferative activity of extracellular HIV-1 Tat protein in human epithelial cells: expression profile of pathogenetically relevant genes. BMC Microbiol. 5 (2005) 20
    • (2005) BMC Microbiol. , vol.5 , pp. 20
    • Bettaccini, A.A.1    Baj, A.2    Accolla, R.S.3    Basolo, F.4    Toniolo, A.Q.5
  • 5
    • 0026442836 scopus 로고
    • Effects of the human immunodeficiency virus type 1 Tat protein on the expression of inflammatory cytokines
    • Buonaguro L., Barillari G., Chang H.K., Bohan C.A., Kao V., Morgan R., Gallo R.C., and Ensoli B. Effects of the human immunodeficiency virus type 1 Tat protein on the expression of inflammatory cytokines. J. Virol. 66 (1992) 7159-7167
    • (1992) J. Virol. , vol.66 , pp. 7159-7167
    • Buonaguro, L.1    Barillari, G.2    Chang, H.K.3    Bohan, C.A.4    Kao, V.5    Morgan, R.6    Gallo, R.C.7    Ensoli, B.8
  • 6
    • 33344464945 scopus 로고    scopus 로고
    • CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment
    • Burger J.A., and Kipps T.J. CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment. Blood 107 (2006) 1761-1767
    • (2006) Blood , vol.107 , pp. 1761-1767
    • Burger, J.A.1    Kipps, T.J.2
  • 8
    • 2942639515 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Tat increases the expression of cleavage and polyadenylation specificity factor 73-kilodalton subunit modulating cellular and viral expression
    • Calzado M.A., Sancho R., and Munoz E. Human immunodeficiency virus type 1 Tat increases the expression of cleavage and polyadenylation specificity factor 73-kilodalton subunit modulating cellular and viral expression. J. Virol. 78 (2004) 6846-6854
    • (2004) J. Virol. , vol.78 , pp. 6846-6854
    • Calzado, M.A.1    Sancho, R.2    Munoz, E.3
  • 11
    • 0032577444 scopus 로고    scopus 로고
    • HIV-1 auxiliary proteins: making connections in a dying cell
    • Cullen B.R. HIV-1 auxiliary proteins: making connections in a dying cell. Cell 93 (1998) 685-692
    • (1998) Cell , vol.93 , pp. 685-692
    • Cullen, B.R.1
  • 12
    • 0034723291 scopus 로고    scopus 로고
    • Beta-arrestin differentially regulates the chemokine receptor CXCR4-mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4
    • Cheng Z.J., Zhao J., Sun Y., Hu W., Wu Y.L., Cen B., Wu G.X., and Pei G. Beta-arrestin differentially regulates the chemokine receptor CXCR4-mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4. J. Biol. Chem. 275 (2000) 2479-2485
    • (2000) J. Biol. Chem. , vol.275 , pp. 2479-2485
    • Cheng, Z.J.1    Zhao, J.2    Sun, Y.3    Hu, W.4    Wu, Y.L.5    Cen, B.6    Wu, G.X.7    Pei, G.8
  • 15
    • 0029805203 scopus 로고    scopus 로고
    • Host factors and the pathogenesis of HIV-induced disease
    • Fauci A.S. Host factors and the pathogenesis of HIV-induced disease. Nature 384 (1996) 529-534
    • (1996) Nature , vol.384 , pp. 529-534
    • Fauci, A.S.1
  • 18
    • 0029026576 scopus 로고
    • Regulation of HIV-1 gene expression by the transactivator protein Tat
    • Gaynor R.B. Regulation of HIV-1 gene expression by the transactivator protein Tat. Curr. Top. Microbiol. Immunol. 193 (1995) 51-77
    • (1995) Curr. Top. Microbiol. Immunol. , vol.193 , pp. 51-77
    • Gaynor, R.B.1
  • 20
    • 0032522663 scopus 로고    scopus 로고
    • Extracellular HIV-1 Tat protein induces the rapid Ser133 phosphorylation and activation of CREB transcription factor in both Jurkat lymphoblastoid T cells and primary peripheral blood mononuclear cells
    • Gibellini D., Bassini A., Pierpaoli S., Bertolaso L., Milani D., Capitani S., La P.M., and Zauli G. Extracellular HIV-1 Tat protein induces the rapid Ser133 phosphorylation and activation of CREB transcription factor in both Jurkat lymphoblastoid T cells and primary peripheral blood mononuclear cells. J. Immunol. 160 (1998) 3891-3898
    • (1998) J. Immunol. , vol.160 , pp. 3891-3898
    • Gibellini, D.1    Bassini, A.2    Pierpaoli, S.3    Bertolaso, L.4    Milani, D.5    Capitani, S.6    La, P.M.7    Zauli, G.8
  • 21
    • 31544473113 scopus 로고    scopus 로고
    • cAMP-induced PKCzeta activation increases functional CXCR4 expression on human CD34+ hematopoietic progenitors
    • Goichberg P., Kalinkovich A., Borodovsky N., Tesio M., Petit I., Nagler A., Hardan I., and Lapidot T. cAMP-induced PKCzeta activation increases functional CXCR4 expression on human CD34+ hematopoietic progenitors. Blood 107 (2006) 870-879
    • (2006) Blood , vol.107 , pp. 870-879
    • Goichberg, P.1    Kalinkovich, A.2    Borodovsky, N.3    Tesio, M.4    Petit, I.5    Nagler, A.6    Hardan, I.7    Lapidot, T.8
  • 23
    • 0035313077 scopus 로고    scopus 로고
    • Hiv-1 tat inhibits il-2 gene transcription through qualitative and quantitative alterations of the cooperative rel/ap1 complex bound to the cd28re/ap1 composite element of the il-2 promoter
    • Gonzalez E., Punzon C., Gonzalez M., and Fresno M. Hiv-1 tat inhibits il-2 gene transcription through qualitative and quantitative alterations of the cooperative rel/ap1 complex bound to the cd28re/ap1 composite element of the il-2 promoter. J. Immunol. 166 (2001) 4560-4569
    • (2001) J. Immunol. , vol.166 , pp. 4560-4569
    • Gonzalez, E.1    Punzon, C.2    Gonzalez, M.3    Fresno, M.4
  • 24
    • 33744808241 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Tat increases cooperation between AP-1 and NFAT transcription factors in T cells
    • Hidalgo-Estevez A.M., Gonzalez E., Punzon C., and Fresno M. Human immunodeficiency virus type 1 Tat increases cooperation between AP-1 and NFAT transcription factors in T cells. J. Gen. Virol. 87 (2006) 1603-1612
    • (2006) J. Gen. Virol. , vol.87 , pp. 1603-1612
    • Hidalgo-Estevez, A.M.1    Gonzalez, E.2    Punzon, C.3    Fresno, M.4
  • 26
    • 23244459907 scopus 로고    scopus 로고
    • Nef proteins from diverse groups of primate lentiviruses downmodulate CXCR4 to inhibit migration to the chemokine stromal derived factor 1
    • Hrecka K., Swigut T., Schindler M., Kirchhoff F., and Skowronski J. Nef proteins from diverse groups of primate lentiviruses downmodulate CXCR4 to inhibit migration to the chemokine stromal derived factor 1. J. Virol. 79 (2005) 10650-10659
    • (2005) J. Virol. , vol.79 , pp. 10650-10659
    • Hrecka, K.1    Swigut, T.2    Schindler, M.3    Kirchhoff, F.4    Skowronski, J.5
  • 27
    • 0031661154 scopus 로고    scopus 로고
    • Tat protein induces human immunodeficiency virus type 1 (HIV-1) coreceptors and promotes infection with both macrophage-tropic and T-lymphotropic HIV-1 strains
    • Huang L., Bosch I., Hofmann W., Sodroski J., and Pardee A.B. Tat protein induces human immunodeficiency virus type 1 (HIV-1) coreceptors and promotes infection with both macrophage-tropic and T-lymphotropic HIV-1 strains. J. Virol. 72 (1998) 8952-8960
    • (1998) J. Virol. , vol.72 , pp. 8952-8960
    • Huang, L.1    Bosch, I.2    Hofmann, W.3    Sodroski, J.4    Pardee, A.B.5
  • 29
    • 0034604683 scopus 로고    scopus 로고
    • An essential role of the nuclear factor of activated T cells in the regulation of the expression of the cyclooxygenase-2 gene in human T lymphocytes
    • Iniguez M.A., Martinez-Martinez S., Punzon C., Redondo J.M., and Fresno M. An essential role of the nuclear factor of activated T cells in the regulation of the expression of the cyclooxygenase-2 gene in human T lymphocytes. J. Biol. Chem. 275 (2000) 23627-23635
    • (2000) J. Biol. Chem. , vol.275 , pp. 23627-23635
    • Iniguez, M.A.1    Martinez-Martinez, S.2    Punzon, C.3    Redondo, J.M.4    Fresno, M.5
  • 30
    • 0037330043 scopus 로고    scopus 로고
    • HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages
    • Izmailova E., Bertley F.M., Huang Q., Makori N., Miller C.J., Young R.A., and Aldovini A. HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages. Nat. Med. 9 (2003) 191-197
    • (2003) Nat. Med. , vol.9 , pp. 191-197
    • Izmailova, E.1    Bertley, F.M.2    Huang, Q.3    Makori, N.4    Miller, C.J.5    Young, R.A.6    Aldovini, A.7
  • 31
    • 0027260617 scopus 로고
    • In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factor
    • Jeang K.T., Chun R., Lin N.H., Gatignol A., Glabe C.G., and Fan H. In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factor. J. Virol. 67 (1993) 6224-6233
    • (1993) J. Virol. , vol.67 , pp. 6224-6233
    • Jeang, K.T.1    Chun, R.2    Lin, N.H.3    Gatignol, A.4    Glabe, C.G.5    Fan, H.6
  • 32
    • 0035794637 scopus 로고    scopus 로고
    • The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation
    • Jordan A., Defechereux P., and Verdin E. The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation. EMBO J. 20 (2001) 1726-1738
    • (2001) EMBO J. , vol.20 , pp. 1726-1738
    • Jordan, A.1    Defechereux, P.2    Verdin, E.3
  • 33
    • 0031747997 scopus 로고    scopus 로고
    • The role of receptor kinases and arrestins in G protein-coupled receptor regulation
    • Krupnick J.G., and Benovic J.L. The role of receptor kinases and arrestins in G protein-coupled receptor regulation. Annu. Rev. Pharmacol. Toxicol. 38 (1998) 289-319
    • (1998) Annu. Rev. Pharmacol. Toxicol. , vol.38 , pp. 289-319
    • Krupnick, J.G.1    Benovic, J.L.2
  • 35
    • 6344293549 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1 (SDF-1)\CXCR4 couple plays multiple roles on haematopoietic progenitors at the border between the old cytokine and new chemokine worlds: survival, cell cycling and trafficking
    • Lataillade J.J., Domenech J., and Le Bousse-Kerdiles M.C. Stromal cell-derived factor-1 (SDF-1)\CXCR4 couple plays multiple roles on haematopoietic progenitors at the border between the old cytokine and new chemokine worlds: survival, cell cycling and trafficking. Eur. Cytokine Netw. 15 (2004) 177-188
    • (2004) Eur. Cytokine Netw. , vol.15 , pp. 177-188
    • Lataillade, J.J.1    Domenech, J.2    Le Bousse-Kerdiles, M.C.3
  • 36
    • 0029062573 scopus 로고
    • Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein
    • Li C.J., Friedman D.J., Wang C., Metelev V., and Pardee A.B. Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein. Science 268 (1995) 429-431
    • (1995) Science , vol.268 , pp. 429-431
    • Li, C.J.1    Friedman, D.J.2    Wang, C.3    Metelev, V.4    Pardee, A.B.5
  • 37
    • 32544446940 scopus 로고    scopus 로고
    • HIV and the chemokine system: 10 years later
    • Lusso P. HIV and the chemokine system: 10 years later. EMBO J. 25 (2006) 447-456
    • (2006) EMBO J. , vol.25 , pp. 447-456
    • Lusso, P.1
  • 38
    • 0032908409 scopus 로고    scopus 로고
    • Reciprocal modulatory interaction between human immunodeficiency virus type 1 Tat and transcription factor NFAT1
    • Macián F., and Rao A. Reciprocal modulatory interaction between human immunodeficiency virus type 1 Tat and transcription factor NFAT1. Mol. Cell. Biol. 19 (1999) 3645-3653
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 3645-3653
    • Macián, F.1    Rao, A.2
  • 39
    • 0038487327 scopus 로고    scopus 로고
    • The ins and outs of G protein-coupled receptor trafficking
    • Marchese A., Chen C., Kim Y.M., and Benovic J.L. The ins and outs of G protein-coupled receptor trafficking. Trends Biochem. Sci. 28 (2003) 369-376
    • (2003) Trends Biochem. Sci. , vol.28 , pp. 369-376
    • Marchese, A.1    Chen, C.2    Kim, Y.M.3    Benovic, J.L.4
  • 41
    • 0035844233 scopus 로고    scopus 로고
    • Regulation of nuclear factor kappa B transactivation. Implication of phosphatidylinositol 3-kinase and protein kinase C zeta in c-Rel activation by tumor necrosis factor alpha
    • Martin A.G., San-Antonio B., and Fresno M. Regulation of nuclear factor kappa B transactivation. Implication of phosphatidylinositol 3-kinase and protein kinase C zeta in c-Rel activation by tumor necrosis factor alpha. J. Biol. Chem. 276 (2001) 15840-15849
    • (2001) J. Biol. Chem. , vol.276 , pp. 15840-15849
    • Martin, A.G.1    San-Antonio, B.2    Fresno, M.3
  • 43
    • 27144557035 scopus 로고    scopus 로고
    • The HIV-1 Tat protein selectively enhances CXCR4 and inhibits CCR5 expression in megakaryocytic K562 cells
    • Mondal D., Williams C.A., Ali M., Eilers M., and Agrawal K.C. The HIV-1 Tat protein selectively enhances CXCR4 and inhibits CCR5 expression in megakaryocytic K562 cells. Exp. Biol. Med. (Maywood) 230 (2005) 631-644
    • (2005) Exp. Biol. Med. (Maywood) , vol.230 , pp. 631-644
    • Mondal, D.1    Williams, C.A.2    Ali, M.3    Eilers, M.4    Agrawal, K.C.5
  • 44
    • 33645960166 scopus 로고    scopus 로고
    • PKCzeta at the crossroad of NF-kappaB and Jak1/Stat6 signaling pathways
    • Moscat J., Rennert P., and Diaz-Meco M.T. PKCzeta at the crossroad of NF-kappaB and Jak1/Stat6 signaling pathways. Cell Death Differ. 13 (2006) 702-711
    • (2006) Cell Death Differ. , vol.13 , pp. 702-711
    • Moscat, J.1    Rennert, P.2    Diaz-Meco, M.T.3
  • 45
    • 0034544508 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1-CXC chemokine receptor 4 interactions play a central role in CD4+ T cell accumulation in rheumatoid arthritis synovium
    • Nanki T., Hayashida K., El-Gabalawy H.S., Suson S., Shi K., Girschick H.J., Yavuz S., and Lipsky P.E. Stromal cell-derived factor-1-CXC chemokine receptor 4 interactions play a central role in CD4+ T cell accumulation in rheumatoid arthritis synovium. J. Immunol. 165 (2000) 6590-6598
    • (2000) J. Immunol. , vol.165 , pp. 6590-6598
    • Nanki, T.1    Hayashida, K.2    El-Gabalawy, H.S.3    Suson, S.4    Shi, K.5    Girschick, H.J.6    Yavuz, S.7    Lipsky, P.E.8
  • 46
    • 0032742818 scopus 로고    scopus 로고
    • Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalisation
    • Orsini M.J., Parent J.L., Mundell S.J., Benovic J.L., and Marchese A. Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalisation. J. Biol. Chem. 274 (1999) 31076-31086
    • (1999) J. Biol. Chem. , vol.274 , pp. 31076-31086
    • Orsini, M.J.1    Parent, J.L.2    Mundell, S.J.3    Benovic, J.L.4    Marchese, A.5
  • 48
    • 0032521286 scopus 로고    scopus 로고
    • Superinduction of IL-8 in T cells by HIV-1 Tat protein is mediated through NF-kappaB factors
    • Ott M., Lovett J.L., Mueller L., and Verdin E. Superinduction of IL-8 in T cells by HIV-1 Tat protein is mediated through NF-kappaB factors. J. Immunol. 160 (1998) 2872-2880
    • (1998) J. Immunol. , vol.160 , pp. 2872-2880
    • Ott, M.1    Lovett, J.L.2    Mueller, L.3    Verdin, E.4
  • 49
    • 7244243898 scopus 로고    scopus 로고
    • Human in vivo-activated CD45R0(+) CD4(+) T cells are susceptible to spontaneous apoptosis that can be inhibited by the chemokine CXCL12 and IL-2, -6, -7, and -15
    • Pajusto M., Ihalainen N., Pelkonen J., Tarkkanen J., and Mattila P.S. Human in vivo-activated CD45R0(+) CD4(+) T cells are susceptible to spontaneous apoptosis that can be inhibited by the chemokine CXCL12 and IL-2, -6, -7, and -15. Eur. J. Immunol. 34 (2004) 2771-2780
    • (2004) Eur. J. Immunol. , vol.34 , pp. 2771-2780
    • Pajusto, M.1    Ihalainen, N.2    Pelkonen, J.3    Tarkkanen, J.4    Mattila, P.S.5
  • 50
    • 0035903669 scopus 로고    scopus 로고
    • Beta-arrestin- and c-Src-dependent degradation of G-protein-coupled receptor kinase 2
    • Penela P., Elorza A., Sarnago S., and Mayor Jr. F. Beta-arrestin- and c-Src-dependent degradation of G-protein-coupled receptor kinase 2. EMBO J. 20 (2001) 5129-5138
    • (2001) EMBO J. , vol.20 , pp. 5129-5138
    • Penela, P.1    Elorza, A.2    Sarnago, S.3    Mayor Jr., F.4
  • 51
    • 0028277327 scopus 로고
    • Control of T lymphocyte activation and IL-2 receptor expression by endogenously secreted lymphokines
    • Pimentel-Muiños F.X., Muñoz-Fernández M.A., and Fresno M. Control of T lymphocyte activation and IL-2 receptor expression by endogenously secreted lymphokines. J. Immunol. 152 (1994) 5714-5722
    • (1994) J. Immunol. , vol.152 , pp. 5714-5722
    • Pimentel-Muiños, F.X.1    Muñoz-Fernández, M.A.2    Fresno, M.3
  • 52
    • 0028997132 scopus 로고
    • Constitutive expression of human immunodeficiency virus type 1 tat gene inhibits interleukin 2 and interleukin 2 receptor expression in a human CD4+ T lymphoid (H9) cell line
    • Puri R.K., Leland P., and Aggarwal B.B. Constitutive expression of human immunodeficiency virus type 1 tat gene inhibits interleukin 2 and interleukin 2 receptor expression in a human CD4+ T lymphoid (H9) cell line. AIDS Res. Hum. Retroviruses 11 (1995) 31-40
    • (1995) AIDS Res. Hum. Retroviruses , vol.11 , pp. 31-40
    • Puri, R.K.1    Leland, P.2    Aggarwal, B.B.3
  • 53
    • 0142259696 scopus 로고    scopus 로고
    • Timeline: AIDS pathogenesis: what have two decades of HIV research taught us?
    • Rowland-Jones S.L. Timeline: AIDS pathogenesis: what have two decades of HIV research taught us?. Nat. Rev. Immunol. 3 (2003) 343-348
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 343-348
    • Rowland-Jones, S.L.1
  • 54
    • 0037178289 scopus 로고    scopus 로고
    • Protein kinase C zeta phosphorylates nuclear factor of activated T cells and regulates its transactivating activity
    • San-Antonio B., Iniguez M.A., and Fresno M. Protein kinase C zeta phosphorylates nuclear factor of activated T cells and regulates its transactivating activity. J. Biol. Chem. 277 (2002) 27073-27080
    • (2002) J. Biol. Chem. , vol.277 , pp. 27073-27080
    • San-Antonio, B.1    Iniguez, M.A.2    Fresno, M.3
  • 55
    • 0039129153 scopus 로고    scopus 로고
    • Expression of human immunodeficiency virus type I tat results in down-regulation of bcl-2 and induction of apoptosis in hematopoietic cells
    • Sastry K.J., Marin M.C., Nehete P.N., McConnell K., el N.A., and McDonnell T.J. Expression of human immunodeficiency virus type I tat results in down-regulation of bcl-2 and induction of apoptosis in hematopoietic cells. Oncogene 13 (1996) 487-493
    • (1996) Oncogene , vol.13 , pp. 487-493
    • Sastry, K.J.1    Marin, M.C.2    Nehete, P.N.3    McConnell, K.4    el, N.A.5    McDonnell, T.J.6
  • 56
    • 0033558358 scopus 로고    scopus 로고
    • Extracellular HIV-1 tat protein up-regulates the expression of surface CXC-chemokine receptor 4 in resting CD4+ T cells
    • Secchiero P., Zella D., Capitani S., Gallo R.C., and Zauli G. Extracellular HIV-1 tat protein up-regulates the expression of surface CXC-chemokine receptor 4 in resting CD4+ T cells. J. Immunol. 162 (1999) 2427-2431
    • (1999) J. Immunol. , vol.162 , pp. 2427-2431
    • Secchiero, P.1    Zella, D.2    Capitani, S.3    Gallo, R.C.4    Zauli, G.5
  • 58
    • 0038299654 scopus 로고    scopus 로고
    • HIV-1 pathogenesis
    • Stevenson M. HIV-1 pathogenesis. Nat. Med. 9 (2003) 853-860
    • (2003) Nat. Med. , vol.9 , pp. 853-860
    • Stevenson, M.1
  • 59
    • 0032209522 scopus 로고    scopus 로고
    • Signaling through protein kinase C
    • Toker A. Signaling through protein kinase C. Front. Biosci. 3 (1998) D1134-D1147
    • (1998) Front. Biosci. , vol.3
    • Toker, A.1
  • 61
    • 1642506294 scopus 로고    scopus 로고
    • GRK6 deficiency is associated with enhanced CXCR4-mediated neutrophil chemotaxis in vitro and impaired responsiveness to G-CSF in vivo
    • Vroon A., Heijnen C.J., Raatgever R., Touw I.P., Ploemacher R.E., Premont R.T., and Kavelaars A. GRK6 deficiency is associated with enhanced CXCR4-mediated neutrophil chemotaxis in vitro and impaired responsiveness to G-CSF in vivo. J. Leukoc. Biol. 75 (2004) 698-704
    • (2004) J. Leukoc. Biol. , vol.75 , pp. 698-704
    • Vroon, A.1    Heijnen, C.J.2    Raatgever, R.3    Touw, I.P.4    Ploemacher, R.E.5    Premont, R.T.6    Kavelaars, A.7
  • 62
    • 0028271114 scopus 로고
    • Human immunodeficiency virus type 1 Tat upregulates interleukin-2 secretion in activated T cells
    • Westendorp M.O., Li W.M., Frank R.W., and Krammer P.H. Human immunodeficiency virus type 1 Tat upregulates interleukin-2 secretion in activated T cells. J. Virol. 68 (1994) 4177-4185
    • (1994) J. Virol. , vol.68 , pp. 4177-4185
    • Westendorp, M.O.1    Li, W.M.2    Frank, R.W.3    Krammer, P.H.4
  • 65
    • 0027096251 scopus 로고
    • tat protein stimulates production of transforming growth factor-beta 1 by marrow macrophages: a potential mechanism for human immunodeficiency virus-1-induced hematopoietic suppression
    • Zauli G., Davis B.R., Re M.C., Visani G., Furlini G., and La P.M. tat protein stimulates production of transforming growth factor-beta 1 by marrow macrophages: a potential mechanism for human immunodeficiency virus-1-induced hematopoietic suppression. Blood 80 (1992) 3036-3043
    • (1992) Blood , vol.80 , pp. 3036-3043
    • Zauli, G.1    Davis, B.R.2    Re, M.C.3    Visani, G.4    Furlini, G.5    La, P.M.6
  • 66
    • 0027424166 scopus 로고
    • Human immunodeficiency virus type 1 Tat protein protects lymphoid, epithelial, and neuronal cell lines from death by apoptosis
    • Zauli G., Gibellini D., Milani D., Mazzoni M., Borgatti P., La P.M., and Capitani S. Human immunodeficiency virus type 1 Tat protein protects lymphoid, epithelial, and neuronal cell lines from death by apoptosis. Cancer Res. 53 (1993) 4481-4485
    • (1993) Cancer Res. , vol.53 , pp. 4481-4485
    • Zauli, G.1    Gibellini, D.2    Milani, D.3    Mazzoni, M.4    Borgatti, P.5    La, P.M.6    Capitani, S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.