Inflammatory markers and negative mood symptoms following exercise withdrawal

Brain, Behavior, and Immunity

Volumn 22, Issue 8, 2008, Pages 1190-1196

  Kop, Willem J ^a   Weinstein, Ali A ^b   Deuster, Patricia A ^c   Whittaker, Kerry S ^c   Tracy, Russell P ^d  

^a UNIVERSITY OF MARYLAND MEDICAL CENTER   (United States)

^b GEORGE MASON UNIVERSITY   (United States)

^c Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center   (United States)

^d UNIVERSITY OF VERMONT   (United States)

Author keywords

Autonomic nervous system; CRP; Depression; Exercise; Fatigue; Fibrinogen; Heart rate variability; Inflammation; Interleukin 6; Mood; Physical activity

Indexed keywords

C REACTIVE PROTEIN; FIBRINOGEN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6;

ACTIMETRY; ADULT; AEROBIC EXERCISE; ARTICLE; AUTONOMIC NEUROPATHY; BECK DEPRESSION INVENTORY; BRAIN FUNCTION; CONTROLLED STUDY; DEPRESSION; EXERCISE; EXERCISE WITHDRAWAL; FATIGUE; FEEDBACK SYSTEM; FEMALE; HEART RATE VARIABILITY; HUMAN; INFLAMMATION; MALE; MOOD DISORDER; MULTIDIMENSIONAL FATIGUE INVENTORY; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; NEGATIVE SYNDROME; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PROFILE OF MOOD STATES;

ADULT; AFFECTIVE SYMPTOMS; ANALYSIS OF VARIANCE; AUTONOMIC NERVOUS SYSTEM; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; ELECTROCARDIOGRAPHY; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXERCISE; FATIGUE; FEMALE; FIBRINOGEN; HEART RATE; HUMANS; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-6; MALE; PATIENT SELECTION;

EID: 52949098712     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbi.2008.05.011     Document Type: Article

References (58)

1. Ainsworth B.E., Haskell W.L., Whitt M.C., Irwin M.L., Swartz A.M., Strath S.J., et al. Compendium of physical activities: an update of activity codes and MET intensities. Med. Sci. Sports Exerc. 32 (2000) S498-S504
2. American College of Sports Medicine. American College of Sports Medicine Position Stand. The recommended quantity and quality of exercise for developing and maintaining cardiorespiratory and muscular fitness, and flexibility in healthy adults. Med. Sci. Sports Exerc. 30 (1998) 975-991
3. Armstrong E.J., Morrow D.A., and Sabatine M.S. Inflammatory biomarkers in acute coronary syndromes: part II: acute-phase reactants and biomarkers of endothelial cell activation. Circulation 113 (2006) e152-e155
4. Beck A.T., Steer R.A., and Brown C. The Beck Depression Inventory Manual. second ed. (1996), The Psychological Corporation, San Antonio, TX
5. Berlin A.A., Kop W.J., and Deuster P.A. Depressive mood symptoms and fatigue after exercise withdrawal: the potential role of decreased fitness. Psychosom. Med. 68 (2006) 224-230
6. Berntson G.G., Bigger J.T., Eckberg D.L., Grossman P., Kaufman P.G., Malik M., et al. Heart rate variability: origins, methods, and interpretive caveats. Psychophysiology 34 (1997) 623-648
7. Bruunsgaard H. Physical activity and modulation of systemic low-level inflammation. J. Leukoc. Biol. 78 (2005) 819-835
8. Capuron L., Ravaud A., Miller A.H., and Dantzer R. Baseline mood and psychosocial characteristics of patients developing depressive symptoms during interleukin-2 and/or interferon-alpha cancer therapy. Brain Behav. Immun. 18 (2004) 205-213
9. Conboy J.K. The effects of exercise withdrawal on mood states in runners. J. Sport Behav. 17 (1994) 188-204
10. Cushman M., Cornell E.S., Howard P.R., Bovill E.G., and Tracy R.P. Laboratory methods and quality assurance in the Cardiovascular Health Study. Clin. Chem. 41 (1995) 264-270
11. Danesh J., Wheeler J.G., Hirschfield G.M., Eda S., Eiriksdottir G., Rumley A., et al. C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. N. Engl. J. Med. 350 (2004) 1387-1397
12. Dantzer R. Cytokine, sickness behavior, and depression. Neurol. Clin. 24 (2006) 441-460
13. Dantzer R., and Kelley K.W. Stress and immunity: an integrated view of relationships between the brain and the immune system. Life Sci. 44 (1989) 1995-2008
14. Dunn A.L., Trivedi M.H., and O'Neal H.A. Physical activity dose-response effects on outcomes of depression and anxiety. Med. Sci. Sports Exerc. 33 (2001) S587-S597
15. Feldman M., Jialal I., Devaraj S., and Cryer B. Effects of low-dose aspirin on serum C-reactive protein and thromboxane B2 concentrations: a placebo-controlled study using a highly sensitive C-reactive protein assay. J. Am. Coll. Cardiol. 37 (2001) 2036-2041
16. Feng D., Tracy R.P., Lipinska I., Murillo J., McKenna C., and Tofler G.H. Effect of short-term aspirin use on C-reactive protein. J. Thromb. Thrombolysis 9 (2000) 37-41
17. Glass J.M., Lyden A.K., Petzke F., Stein P., Whalen G., Ambrose K., et al. The effect of brief exercise cessation on pain, fatigue, and mood symptom development in healthy, fit individuals. J. Psychosom. Res. 57 (2004) 391-398
18. Grossman P., and Taylor E.W. Toward understanding respiratory sinus arrhythmia: relations to cardiac vagal tone, evolution and biobehavioral functions. Biol. Psychol. 74 (2007) 263-285
19. Hamer M. The relative influences of fitness and fatness on inflammatory factors. Prev. Med. 44 (2007) 3-11
20. Harris T.B., Ferrucci L., Tracy R.P., Corti M.C., Wacholder S., Ettinger Jr. W.H., et al. Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly. Am. J. Med. 106 (1999) 506-512
21. Jenny N.S., Arnold A.M., Kuller L.H., Sharrett A.R., Fried L.P., Psaty B.M., et al. Soluble intracellular adhesion molecule-1 is associated with cardiovascular disease risk and mortality in older adults. J. Thromb. Haemost. 4 (2006) 107-113
22. Jenny N.S., Tracy R.P., Ogg M.S., Luong l.A., Kuller L.H., Arnold A.M., et al. In the elderly, interleukin-6 plasma levels and the -174G>C polymorphism are associated with the development of cardiovascular disease. Arterioscler. Thromb. Vasc. Biol. 22 (2002) 2066-2071
23. Kohl H.W., Blair S.N., Paffenbarger Jr. R.S., Macera C.A., and Kronenfeld J.J. A mail survey of physical activity habits as related to measured physical fitness. Am. J. Epidemiol. 127 (1988) 1228-1239
24. Kop W.J., and Gottdiener J.S. The role of immune system parameters in the relationship between depression and coronary artery disease. Psychosom. Med. 67 (2005) 537-541
25. Kop W.J., Gottdiener J.S., Tangen C.M., Fried L.P., McBurnie M.A., Walston J., et al. Inflammation and coagulation factors in persons >65 years of age with symptoms of depression but without evidence of myocardial ischemia. Am. J. Cardiol. 89 (2002) 419-424
26. Kop W.J., Lyden A., Berlin A.A., Ambrose K., Olsen C., Gracely R.H., et al. Ambulatory monitoring of physical activity and symptoms in fibromyalgia and chronic fatigue syndrome. Arthritis Rheum. 52 (2005) 296-303
27. Kuller L.H., Tracy R.P., Shaten J., and Meilahn E.N. Relation of C-reactive protein and coronary heart disease in the MRFIT nested case-control study. Multiple Risk Factor Intervention Trial. Am. J. Epidemiol. 144 (1996) 537-547
28. Lanquillon S., Krieg J.C., ing-Abu-Shach U., and Vedder H. Cytokine production and treatment response in major depressive disorder. Neuropsychopharmacology 22 (2000) 370-379
29. Libby P. Inflammation in atherosclerosis. Nature 420 (2002) 868-874
30. Macy E.M., Hayes T.E., and Tracy R.P. Variability in the measurement of C-reactive protein in healthy subjects: implications for reference intervals and epidemiological applications. Clin. Chem. 43 (1997) 52-58
31. Maier S.F., and Watkins L.R. Cytokines for psychologists: implications of bidirectional immune-to-brain communication for understanding behavior, mood, and cognition. Psychol. Rev. 105 (1998) 83-107
32. Mattusch F., Dufaux B., Heine O., Mertens I., and Rost R. Reduction of the plasma concentration of C-reactive protein following nine months of endurance training. Int. J. Sports Med. 21 (2000) 21-24
33. McNair D.M., Lorr M., and Droppleman L.F. Manual for the Profile of Mood States (1971), Educational and Testing Service, San Diego
34. Mora S., Lee I.M., Buring J.E., and Ridker P.M. Association of physical activity and body mass index with novel and traditional cardiovascular biomarkers in women. JAMA 295 (2006) 1412-1419
35. Morris M., Steinberg H., Sykes E.A., and Salmon P. Effects of temporary withdrawal from regular running. J. Psychosom. Res. 34 (1990) 493-500
36. Musselman D.L., Lawson D.H., Gumnick J.F., Manatunga A.K., Penna S., Goodkin R.S., et al. Paroxetine for the prevention of depression induced by high-dose interferon alfa. N. Engl. J. Med. 344 (2001) 961-966
37. O'Brien S.M., Scully P., Fitzgerald P., Scott L.V., and Dinan T.G. Plasma cytokine profiles in depressed patients who fail to respond to selective serotonin reuptake inhibitor therapy. J. Psychiatr. Res. 41 (2007) 326-331
38. Pardo Y., Merz C.N., Paul-Labrador M., Velasquez I., Gottdiener J.S., Kop W.J., et al. Heart rate variability reproducibility and stability using commercially available equipment in coronary artery disease with daily life myocardial ischemia. Am. J. Cardiol. 78 (1996) :866-870
39. Patterson S.M., Krantz D.S., Montgomery L.C., Deuster P.A., Hedges S.M., and Nebel L.E. Automated physical activity monitoring: validation and comparison with physiological and self-report measures. Psychophysiology 30 (1993) 296-305
40. Penedo F.J., and Dahn J.R. Exercise and well-being: a review of mental and physical health benefits associated with physical activity. Curr. Opin. Psychiatry 18 (2005) 189-193
41. Puyau M.R., Adolph A.L., Vohra F.A., and Butte N.F. Validation and calibration of physical activity monitors in children. Obes. Res. 10 (2002) 150-157
42. Ross R. Atherosclerosis-an inflammatory disease. N. Engl. J. Med. 340 (1999) 115-126
43. Sajadieh A., Nielsen O.W., Rasmussen V., Hein H.O., Abedini S., and Hansen J.F. Increased heart rate and reduced heart-rate variability are associated with subclinical inflammation in middle-aged and elderly subjects with no apparent heart disease. Eur. Heart J. 25 (2004) 363-370
44. Segerstrom S.C., and Miller G.E. Psychological stress and the human immune system: a meta-analytic study of 30 years of inquiry. Psychol. Bull. 130 (2004) 601-630
45. Smets E.M., Garssen B., Bonke B., and De Haes J.C. The Multidimensional Fatigue Inventory (MFI) psychometric qualities of an instrument to assess fatigue. J. Psychosom. Res. 39 (1995) 315-325
46. Smith J.K. Exercise and atherogenesis. Exerc. Sport Sci. Rev. 29 (2001) 49-53
47. Swain D.P., and Wright R.L. Prediction of VO2 peak from submaximal cycle ergometry using 50 versus 80 rpm. Med. Sci. Sports Exerc. 29 (1997) 268-272
48. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Heart rate variability: standards of measurement, physiological interpretation, and clinical use. Circulation 93 (1996) 1043-1065
49. Thayer J.F., and Sternberg E. Beyond heart rate variability: vagal regulation of allostatic systems. Ann. NY Acad. Sci. 1088 (2006) 361-372
50. Tracy R.P., Bovill E.G., Yanez D., Psaty B.M., Fried L.P., Heiss G., et al. Fibrinogen and factor VIII, but not factor VII, are associated with measures of subclinical cardiovascular disease in the elderly. Results from The Cardiovascular Health Study. Arterioscler. Thromb. Vasc. Biol. 15 (1995) 1269-1279
51. Tracy R.P., Lemaitre R.N., Psaty B.M., Ives D.G., Evans R.W., Cushman M., et al. Relationship of C-reactive protein to risk of cardiovascular disease in the elderly. Results from the cardiovascular health study and the rural health promotion project. Arterioscler. Thromb. Vasc. Biol. 17 (1997) 1121-1127
52. Verdaet D., Dendale P., De B.D., Delanghe J., Block P., and De B.G. Association between leisure time physical activity and markers of chronic inflammation related to coronary heart disease. Atherosclerosis 176 (2004) 303-310
53. Vollmer-Conna U., Fazou C., Cameron B., Li H., Brennan C., Luck L., et al. Production of pro-inflammatory cytokines correlates with the symptoms of acute sickness behaviour in humans. Psychol. Med. 34 (2004) 1289-1297
54. Weinstein A.A., Deuster P.A., and Kop W.J. Heart rate variability as a predictor of negative mood symptoms induced by exercise withdrawal. Med. Sci. Sports Exerc. 39 (2007) 735-741
55. Wilund K.R. Is the anti-inflammatory effect of regular exercise responsible for reduced cardiovascular disease?. Clin. Sci. (Lond.) 112 (2007) 543-555
56. Woodward M., Lowe G.D., Francis L.M., Rumley A., and Cobbe S.M. A randomized comparison of the effects of aspirin and clopidogrel on thrombotic risk factors and C-reactive protein following myocardial infarction: the CADET trial. J. Thromb. Haemost. 2 (2004) 1934-1940
57. Wright C.E., Strike P.C., Brydon L., and Steptoe A. Acute inflammation and negative mood: mediation by cytokine activation. Brain Cogn. 19 (2005) 345-350
58. Yeung R.R. The acute effects of exercise on mood state. J. Psychosom. Res. 40 (1996) 123-141