Identification of in vitro inhibitors of Mycobacterium tuberculosis Lysine ε-aminotransferase by pharmacophore mapping and three-dimensional flexible searches

Medicinal Chemistry Research

Volumn 17, Issue 2-7, 2008, Pages 182-188

  Dube, Divya ^a   Tripathi, Sarvind Mani ^a   Ramachandran, Ravishankar ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Inhibitor; Lysine e aminotransferase; Mycobacterium tuberculosis; Virtual screening

Indexed keywords

AMINOTRANSFERASE INHIBITOR; CYCLOHEXYLMETHYL AMINE DERIVATIVE; HEXAHYDROISOINDOLE 1,3 DIONE; LYSINE 6 AMINOTRANSFERASE; UNCLASSIFIED DRUG;

CONFERENCE PAPER; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME STRUCTURE; IN VITRO STUDY; MYCOBACTERIUM TUBERCULOSIS; PHARMACOPHORE;

EID: 52949090415     PISSN: 10542523     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00044-007-9048-1     Document Type: Conference Paper

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