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Volumn 4, Issue 4, 2008, Pages 797-802

The treatment of chronic hepatitis B: Focus on adefovir-like antivirals

Author keywords

Adefovir; Almefovir; Antiviral therapy; Hepatitis B; Pradefovir; Tenofovir

Indexed keywords

2 AMINO 9 (1 PHOSPHONOMETHOXYCYCLOPROPYLMETHYL)PURINE BIS(PIVALOYLOXYMETHYL) ESTER; ADEFOVIR; ADEFOVIR DIPIVOXIL; ALAMIFOVIR; CYTOCHROME P450 3A4; DRUG METABOLIZING ENZYME; ENTECAVIR; LAMIVUDINE; PLACEBO; PRADEFOVIR; TELBIVUDINE; TENOFOVIR; TENOFOVIR DISOPROXIL; VIRUS DNA;

EID: 52949083548     PISSN: 11766336     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (7)

References (55)
  • 1
    • 33947125928 scopus 로고    scopus 로고
    • Interferon-alpha and ribavirin resistance of Huh7 cells transfected with HCV subgenomic replicon
    • Aus dem Siepen M, Oniangue-Ndza C, Wiese M, et al. 2007. Interferon-alpha and ribavirin resistance of Huh7 cells transfected with HCV subgenomic replicon. Virus Res, 125:109-13.
    • (2007) Virus Res , vol.125 , pp. 109-113
    • Aus dem Siepen, M.1    Oniangue-Ndza, C.2    Wiese, M.3
  • 2
    • 34247352929 scopus 로고    scopus 로고
    • Gene and protein expression of P-glycoprotein, MRP1, MRP2, and CYP3A4 in the small and large human intestine
    • Berggren S, Gall C, Wollnitz N, et al. 2007. Gene and protein expression of P-glycoprotein, MRP1, MRP2, and CYP3A4 in the small and large human intestine. Mol Pharm, 4:252-7.
    • (2007) Mol Pharm , vol.4 , pp. 252-257
    • Berggren, S.1    Gall, C.2    Wollnitz, N.3
  • 3
    • 20944444466 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of alamifovir and its metabolites
    • Chan C, Abu-Raddad E, Golor G, et al. 2005. Clinical pharmacokinetics of alamifovir and its metabolites. Antimicrob Agents Chemother, 49:1813-22.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 1813-1822
    • Chan, C.1    Abu-Raddad, E.2    Golor, G.3
  • 4
    • 33644818518 scopus 로고    scopus 로고
    • A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B
    • Chang TT, Gish RG, de Man R, et al. 2006. A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B. N Engl J Med, 354:1001-10.
    • (2006) N Engl J Med , vol.354 , pp. 1001-1010
    • Chang, T.T.1    Gish, R.G.2    de Man, R.3
  • 5
    • 29944436855 scopus 로고    scopus 로고
    • REVEAL-HBV Study Group. Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level
    • Chen CJ, Yang HI, Su J, et al. 2006. REVEAL-HBV Study Group. Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level. JAMA, 295:65-73.
    • (2006) JAMA , vol.295 , pp. 65-73
    • Chen, C.J.1    Yang, H.I.2    Su, J.3
  • 6
    • 2442661557 scopus 로고    scopus 로고
    • A novel class of phosphonate nucleosides. 9-[(1-phosphonomethoxycyclopropyl)methyl]guanine as a potent and selective anti-HBV agent
    • Choi JR, Cho DG, Roh KY, et al. 2004. A novel class of phosphonate nucleosides. 9-[(1-phosphonomethoxycyclopropyl)methyl]guanine as a potent and selective anti-HBV agent. J Med Chem, 47:2864-9.
    • (2004) J Med Chem , vol.47 , pp. 2864-2869
    • Choi, J.R.1    Cho, D.G.2    Roh, K.Y.3
  • 7
    • 33847622350 scopus 로고    scopus 로고
    • Assessment at three years shows high barrier to resistance is maintained in entecavir-treated nucleoside naïve patients while resistance emergence increases over time in lamivudine refractory patients
    • Colonno RJ, Rose RE, Pokornowski K, et al. 2006. Assessment at three years shows high barrier to resistance is maintained in entecavir-treated nucleoside naïve patients while resistance emergence increases over time in lamivudine refractory patients. Hepatology, 44:229-30.
    • (2006) Hepatology , vol.44 , pp. 229-230
    • Colonno, R.J.1    Rose, R.E.2    Pokornowski, K.3
  • 8
    • 34447344085 scopus 로고    scopus 로고
    • Prophylaxis, diagnosis and therapy of hepatitis-B-virus-(HBV) infection: Upgrade of the guideline. AWMF-Register 021/011
    • Cornberg M, Protzer U, Dollinger MM, et al. 2007. Prophylaxis, diagnosis and therapy of hepatitis-B-virus-(HBV) infection: upgrade of the guideline. AWMF-Register 021/011. Z Gastroenterol, 45:1287-328.
    • (2007) Z Gastroenterol , vol.45 , pp. 1287-1328
    • Cornberg, M.1    Protzer, U.2    Dollinger, M.M.3
  • 11
    • 52949088423 scopus 로고    scopus 로고
    • Switzerland. Consensus statement
    • Geneva, Switzerland. Consensus statement. J Hepatol, 39:3-25.
    • J Hepatol , vol.39 , pp. 3-25
    • Geneva1
  • 12
    • 34548278800 scopus 로고    scopus 로고
    • Low-dose tenofovir is more potent than adefovir and is effective in controlling HBV viremia in chronic HBeAg-negative hepatitis B
    • Del Poggio P, Zaccanelli M, Oggionni M, et al. 2007. Low-dose tenofovir is more potent than adefovir and is effective in controlling HBV viremia in chronic HBeAg-negative hepatitis B. World J Gastroenterol, 13:4096-9.
    • (2007) World J Gastroenterol , vol.13 , pp. 4096-4099
    • Del Poggio, P.1    Zaccanelli, M.2    Oggionni, M.3
  • 13
    • 0033592764 scopus 로고    scopus 로고
    • Lamivudine as initial treatment for chronic hepatitis B in the United States
    • Dienstag JL, Schiff ER, Wright TL, et al. 1999. Lamivudine as initial treatment for chronic hepatitis B in the United States. N Engl J Med, 341:1256-63.
    • (1999) N Engl J Med , vol.341 , pp. 1256-1263
    • Dienstag, J.L.1    Schiff, E.R.2    Wright, T.L.3
  • 16
    • 0037468406 scopus 로고    scopus 로고
    • Adefovir dipivoxil for the treatment of hepatitis B e antigen-negative chronic hepatitis B
    • Hadziyannis SJ, Tassopoulos NC, Heathcote EJ, et al. 2003. Adefovir dipivoxil for the treatment of hepatitis B e antigen-negative chronic hepatitis B. N Engl J Med, 348:800-7.
    • (2003) N Engl J Med , vol.348 , pp. 800-807
    • Hadziyannis, S.J.1    Tassopoulos, N.C.2    Heathcote, E.J.3
  • 17
    • 21244455293 scopus 로고    scopus 로고
    • Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B
    • Hadziyannis SJ, Tassopoulos NC, Heathcote EJ, et al. 2005. Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B. N Engl J Med, 352:2673-81.
    • (2005) N Engl J Med , vol.352 , pp. 2673-2681
    • Hadziyannis, S.J.1    Tassopoulos, N.C.2    Heathcote, E.J.3
  • 18
    • 33845671388 scopus 로고    scopus 로고
    • Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B for up to 5 years
    • Hadziyannis SJ, Tassopoulos NC, Heathcote EJ, et al. 2006. Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B for up to 5 years. Gastroenterology, 131:1743-51.
    • (2006) Gastroenterology , vol.131 , pp. 1743-1751
    • Hadziyannis, S.J.1    Tassopoulos, N.C.2    Heathcote, E.J.3
  • 19
    • 34848847501 scopus 로고    scopus 로고
    • Telbivudine globe trial at year two: Efficacy, safety, and predictors of outcome in patients with chronic hepatitis B
    • Han S, Lai C, Gane EJ, et al. 2007. Telbivudine globe trial at year two: efficacy, safety, and predictors of outcome in patients with chronic hepatitis B. Gastroenterology, 132:765.
    • (2007) Gastroenterology , vol.132 , pp. 765
    • Han, S.1    Lai, C.2    Gane, E.J.3
  • 20
    • 39149122593 scopus 로고    scopus 로고
    • A Randomized, Double-Blind, Comparison of Tenofovir DF (TDF) Versus Adefovir Dipivoxil (ADV) for the Treatment of HBeAg Positive Chronic Hepatitis B (CHB): Study GS-US-174-0103
    • Heathcote EJ, Gane E, De Man R, et al. A Randomized, Double-Blind, Comparison of Tenofovir DF (TDF) Versus Adefovir Dipivoxil (ADV) for the Treatment of HBeAg Positive Chronic Hepatitis B (CHB): Study GS-US-174-0103. Hepatology 2007: (Suppl. 1) 231A.
    • (2007) Hepatology , Issue.SUPPL. 1
    • Heathcote, E.J.1    Gane, E.2    De Man, R.3
  • 21
    • 45549103233 scopus 로고    scopus 로고
    • Tenofovir Disoproxil Fumarate (TDF) for the treatment of HBeAg-positive chronic hepatitis B: Week 72 TDF data and week 24 Adefvoir Dipivoxil switch data (Study 103)
    • Heathcote EJ, George J, Gordon S, et al. Tenofovir Disoproxil Fumarate (TDF) for the treatment of HBeAg-positive chronic hepatitis B: Week 72 TDF data and week 24 Adefvoir Dipivoxil switch data (Study 103). J Hepatol 2008: (Suppl.2) S32.
    • (2008) J Hepatol , Issue.SUPPL.2
    • Heathcote, E.J.1    George, J.2    Gordon, S.3
  • 22
    • 34047267628 scopus 로고    scopus 로고
    • Efficacy and safety of adefovir dipivoxil 20 ing daily in HBeAg-positive patients with lamivudine-resistant hepatitis B virus and a suboptimal virological response to adefovir dipivoxil 10 mg daily
    • Hezode C, Chevaliez S, Bouvier-Alias M, et al. 2007. Efficacy and safety of adefovir dipivoxil 20 ing daily in HBeAg-positive patients with lamivudine-resistant hepatitis B virus and a suboptimal virological response to adefovir dipivoxil 10 mg daily. J Hepatol, 46:791-6.
    • (2007) J Hepatol , vol.46 , pp. 791-796
    • Hezode, C.1    Chevaliez, S.2    Bouvier-Alias, M.3
  • 23
    • 33644858331 scopus 로고    scopus 로고
    • Iloeje UH, Yang HI, Su J, et al; Risk Evaluation of Viral Load Elevation and Associated Liver Diseage/Cancer-In HBV (the REVEAL-HBV) Study Group. 2006. Predicting cirrhosis risk based on the level of circulating hepatitis B viral load. Gastroenterology, 130:678-86.
    • Iloeje UH, Yang HI, Su J, et al; Risk Evaluation of Viral Load Elevation and Associated Liver Diseage/Cancer-In HBV (the REVEAL-HBV) Study Group. 2006. Predicting cirrhosis risk based on the level of circulating hepatitis B viral load. Gastroenterology, 130:678-86.
  • 24
    • 4344623455 scopus 로고    scopus 로고
    • Renal safety of adefovir dipivoxil in patients with chronic hepatitis B: Two double-blind, randomized, placebo-controlled studies
    • Izzedine H, Hulot JS, Launay-Vacher V, et al. 2004. Renal safety of adefovir dipivoxil in patients with chronic hepatitis B: two double-blind, randomized, placebo-controlled studies. Kidney Int, 66:1153-8.
    • (2004) Kidney Int , vol.66 , pp. 1153-1158
    • Izzedine, H.1    Hulot, J.S.2    Launay-Vacher, V.3
  • 25
    • 33644642052 scopus 로고    scopus 로고
    • In vitro characterization of the anti-hepatitis B virus activity and cross-resistance profile of 2′,3′-dideoxy-3′-fluoroguanosine
    • Jacquard AC, Brunelle MN, Pichoud C, et al. 2006. In vitro characterization of the anti-hepatitis B virus activity and cross-resistance profile of 2′,3′-dideoxy-3′-fluoroguanosine. Antimicrob Agents Chemother, 50:955-61.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 955-961
    • Jacquard, A.C.1    Brunelle, M.N.2    Pichoud, C.3
  • 26
    • 0033596267 scopus 로고    scopus 로고
    • Efficacy and safety of adefovir dipivoxil with antiretroviral therapy: A randomized controlled trial
    • Kahn J, Lagakos S, Wulfsohn M, et al. 1999. Efficacy and safety of adefovir dipivoxil with antiretroviral therapy: a randomized controlled trial. JAMA, 24:2305-12.
    • (1999) JAMA , vol.24 , pp. 2305-2312
    • Kahn, J.1    Lagakos, S.2    Wulfsohn, M.3
  • 27
    • 33644822860 scopus 로고    scopus 로고
    • Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B
    • Lai CL, Shouval D, Lok AS, et al. 2006a. Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B. N Engl J Med, 354:1011-20.
    • (2006) N Engl J Med , vol.354 , pp. 1011-1020
    • Lai, C.L.1    Shouval, D.2    Lok, A.S.3
  • 28
    • 33747499810 scopus 로고    scopus 로고
    • Phase II, multi-centre, dose-escalating study of LB8030 (ANA380) in hepatitis B patients with lamivudine resistant YMDD mutant HBV
    • Lai CL, Han KH, Yoon SK, et al. 2006b. Phase II, multi-centre, dose-escalating study of LB8030 (ANA380) in hepatitis B patients with lamivudine resistant YMDD mutant HBV. J Hepatol, 44:5.
    • (2006) J Hepatol , vol.44 , pp. 5
    • Lai, C.L.1    Han, K.H.2    Yoon, S.K.3
  • 29
    • 21244447705 scopus 로고    scopus 로고
    • Peginterferon Alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B
    • Lau GK, Piratvisuth T, Luo KX, et al. 2005. Peginterferon Alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B. N Engl J Med, 352:2682-95.
    • (2005) N Engl J Med , vol.352 , pp. 2682-2695
    • Lau, G.K.1    Piratvisuth, T.2    Luo, K.X.3
  • 30
    • 1642410856 scopus 로고    scopus 로고
    • Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures
    • Lavanchy D. 2004. Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures. J Viral Hepat, 11:97-107.
    • (2004) J Viral Hepat , vol.11 , pp. 97-107
    • Lavanchy, D.1
  • 31
    • 52949128899 scopus 로고    scopus 로고
    • Safety, tolerability and antiviral activity of pradefovir mesylate in patients with chronic hepatitis B virus infection: 48-week analysis of a phase 2 study
    • Lee KS, Lim SG, Chuang WL, et al. 2006. Safety, tolerability and antiviral activity of pradefovir mesylate in patients with chronic hepatitis B virus infection: 48-week analysis of a phase 2 study. J Hepatol, 44:274.
    • (2006) J Hepatol , vol.44 , pp. 274
    • Lee, K.S.1    Lim, S.G.2    Chuang, W.L.3
  • 32
    • 20444363583 scopus 로고    scopus 로고
    • Liaw YF, Leung N, Guan R, et al; Asian-Pacific Consensus Update Working Party on Chronic Hepatitis B. 2005. Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2005 update. Liver Int, 25:472-89.
    • Liaw YF, Leung N, Guan R, et al; Asian-Pacific Consensus Update Working Party on Chronic Hepatitis B. 2005. Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2005 update. Liver Int, 25:472-89.
  • 33
    • 19544391413 scopus 로고    scopus 로고
    • Liaw YF, Sung JJ, Chow WC, et al; Cirrhosis Asian Lamivudine Multicentre Study Group. 2004. Lamivudine for patients with chronic hepatitis B and advanced liver disease. N Engl J Med, 351:1521-31.
    • Liaw YF, Sung JJ, Chow WC, et al; Cirrhosis Asian Lamivudine Multicentre Study Group. 2004. Lamivudine for patients with chronic hepatitis B and advanced liver disease. N Engl J Med, 351:1521-31.
  • 34
    • 33846503973 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of pradefovir mesylate, a liver-targeting pro-drug of PMEA, in HBV patients
    • Lin C, Xu C, Yeh LT, et al. 2006. Pharmacokinetics and pharmacodynamics of pradefovir mesylate, a liver-targeting pro-drug of PMEA, in HBV patients. J Hepatol, 44:16.
    • (2006) J Hepatol , vol.44 , pp. 16
    • Lin, C.1    Xu, C.2    Yeh, L.T.3
  • 35
    • 10644269922 scopus 로고    scopus 로고
    • Remofovir mesylate: A prodrug of PMEA with improved liver-targeting and safety in rats and monkeys
    • Lin CC, Yeh LT, Vitarella D, et al. 2004. Remofovir mesylate: A prodrug of PMEA with improved liver-targeting and safety in rats and monkeys. Antivir Chem Chemother, 15:307-17.
    • (2004) Antivir Chem Chemother , vol.15 , pp. 307-317
    • Lin, C.C.1    Yeh, L.T.2    Vitarella, D.3
  • 36
    • 33847701354 scopus 로고    scopus 로고
    • Chronic hepatitis B
    • Lok AS, McMahon BJ. 2007. Chronic hepatitis B. Hepatology, 45:507-39.
    • (2007) Hepatology , vol.45 , pp. 507-539
    • Lok, A.S.1    McMahon, B.J.2
  • 37
    • 0037468421 scopus 로고    scopus 로고
    • Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B
    • Marcellin P, Chang TT, Lim SG, et al. 2003. Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B. N Engl J Med, 348:808-16.
    • (2003) N Engl J Med , vol.348 , pp. 808-816
    • Marcellin, P.1    Chang, T.T.2    Lim, S.G.3
  • 38
    • 4544239807 scopus 로고    scopus 로고
    • Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B
    • Marcellin P, Lau GK, Bonino F, et al. 2004. Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B. N Engl J Med, 351:1206-17.
    • (2004) N Engl J Med , vol.351 , pp. 1206-1217
    • Marcellin, P.1    Lau, G.K.2    Bonino, F.3
  • 39
    • 52949097413 scopus 로고    scopus 로고
    • Marcellin P, Buti M, Krastev Z, et al. A Randomized, Double-Blind, Comparison of Tenofovir DF (TDF) versus Adefovir Dipivoxil (ADV) for the Treatment of HBeAg-Negative Chronic Hepatitis B (CHB): Study GS-US-174-0102 Hepatology 2007: (Suppl. 1) 231A.
    • Marcellin P, Buti M, Krastev Z, et al. A Randomized, Double-Blind, Comparison of Tenofovir DF (TDF) versus Adefovir Dipivoxil (ADV) for the Treatment of HBeAg-Negative Chronic Hepatitis B (CHB): Study GS-US-174-0102 Hepatology 2007: (Suppl. 1) 231A.
  • 40
    • 45549094638 scopus 로고    scopus 로고
    • Tenofovir Disoproxil Fumarate (TDF) for the treatment of HBeAg-negative chronic hepatitis B: Week 72 TDF data and week 24 Adefvoir Dipivoxil switch data (Study 102)
    • Marcellin P, Jacobson I, Habersetzer F, et al. Tenofovir Disoproxil Fumarate (TDF) for the treatment of HBeAg-negative chronic hepatitis B: Week 72 TDF data and week 24 Adefvoir Dipivoxil switch data (Study 102). J Hepatol 2008: (Suppl.2) S26.
    • (2008) J Hepatol , Issue.SUPPL.2
    • Marcellin, P.1    Jacobson, I.2    Habersetzer, F.3
  • 41
    • 34250722018 scopus 로고    scopus 로고
    • The HBV drug entecavir- effects on HIV-1 replication and resistance
    • McMahon MA, Jilek BL, Brennan TP, et al. 2007. The HBV drug entecavir- effects on HIV-1 replication and resistance. N Engl J Med, 356:2614-21.
    • (2007) N Engl J Med , vol.356 , pp. 2614-2621
    • McMahon, M.A.1    Jilek, B.L.2    Brennan, T.P.3
  • 42
    • 33748114343 scopus 로고    scopus 로고
    • The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide
    • Perz JF, Armstrong GL, Farrington LA, et al. 2006. The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide. J Hepatol, 45:529-38.
    • (2006) J Hepatol , vol.45 , pp. 529-538
    • Perz, J.F.1    Armstrong, G.L.2    Farrington, L.A.3
  • 43
    • 33751002371 scopus 로고    scopus 로고
    • Randomized controlled study of tenofovir and adefovir in chronic hepatitis B virus and HIV infection: ACTG A5127
    • Peters MG, Andersen J, Lynch P, et al. 2006. Randomized controlled study of tenofovir and adefovir in chronic hepatitis B virus and HIV infection: ACTG A5127. Hepatology, 44:1110-6.
    • (2006) Hepatology , vol.44 , pp. 1110-1116
    • Peters, M.G.1    Andersen, J.2    Lynch, P.3
  • 44
    • 33646455583 scopus 로고    scopus 로고
    • HIV-associated renal diseases and highly active antiretroviral therapy-induced nephropathy
    • Röling J, Schmid H, Fischereder M, et al. 2006. HIV-associated renal diseases and highly active antiretroviral therapy-induced nephropathy. Clin Infect Dis, 42:1488-95.
    • (2006) Clin Infect Dis , vol.42 , pp. 1488-1495
    • Röling, J.1    Schmid, H.2    Fischereder, M.3
  • 45
    • 25444459427 scopus 로고    scopus 로고
    • Selection of hepatitis B virus polymerase mutations in HIV-coinfected patients treated with tenofovir
    • Sheldon J, Camino N, Rodes B, et al. 2005. Selection of hepatitis B virus polymerase mutations in HIV-coinfected patients treated with tenofovir. Antivir Ther, 10:727-34.
    • (2005) Antivir Ther , vol.10 , pp. 727-734
    • Sheldon, J.1    Camino, N.2    Rodes, B.3
  • 46
    • 7244248967 scopus 로고    scopus 로고
    • Safety and efficacy of alamifovir in patients with chronic hepatitis B virus infection
    • Soon DK, Lowe SL, Teng CH, et al. 2004. Safety and efficacy of alamifovir in patients with chronic hepatitis B virus infection. J Hepatol, 41:852-8.
    • (2004) J Hepatol , vol.41 , pp. 852-858
    • Soon, D.K.1    Lowe, S.L.2    Teng, C.H.3
  • 47
    • 34248353565 scopus 로고    scopus 로고
    • Treatment of HIV/HBV coinfection: Clinical and virologic issues
    • Thio CL, Locarnini S. 2007. Treatment of HIV/HBV coinfection: clinical and virologic issues. AIDS Rev, 9:40-53.
    • (2007) AIDS Rev , vol.9 , pp. 40-53
    • Thio, C.L.1    Locarnini, S.2
  • 48
    • 34547647033 scopus 로고    scopus 로고
    • Drug evaluation: Pradefovir, a liver-targeted prodrug of adefovir against HBV infection
    • Tillmann HL. 2007. Drug evaluation: Pradefovir, a liver-targeted prodrug of adefovir against HBV infection. Curr Opin Investig Drugs, 8:682-90
    • (2007) Curr Opin Investig Drugs , vol.8 , pp. 682-690
    • Tillmann, H.L.1
  • 49
    • 21344451383 scopus 로고    scopus 로고
    • Reactivation of viral replication after replacement of tenofovir by adefovir
    • van Bommel F, Berg T. 2005. Reactivation of viral replication after replacement of tenofovir by adefovir. Hepatology, 42:239-40.
    • (2005) Hepatology , vol.42 , pp. 239-240
    • van Bommel, F.1    Berg, T.2
  • 50
    • 10644275213 scopus 로고    scopus 로고
    • Comparison of adefovir and tenofovir in the treatment of lamivudine-resistant hepatitis B virus infection
    • van Bommel F, Wunsche T, Mauss S, et al. 2004. Comparison of adefovir and tenofovir in the treatment of lamivudine-resistant hepatitis B virus infection. Hepatology, 40:1421-5.
    • (2004) Hepatology , vol.40 , pp. 1421-1425
    • van Bommel, F.1    Wunsche, T.2    Mauss, S.3
  • 51
    • 33747041958 scopus 로고    scopus 로고
    • Tenofovir for patients with lamivudine-resistant hepatitis B virus (HBV) infection and high HBV DNA level during adefovir therapy
    • van Bommel F, Zollner B, Sarrazin C, et al. 2006. Tenofovir for patients with lamivudine-resistant hepatitis B virus (HBV) infection and high HBV DNA level during adefovir therapy. Hepatology, 44:318-25.
    • (2006) Hepatology , vol.44 , pp. 318-325
    • van Bommel, F.1    Zollner, B.2    Sarrazin, C.3
  • 52
    • 34547971240 scopus 로고    scopus 로고
    • Combination adefovir-lamivudine prevents emergence of adefovir resistance in lamivudine-resistant hepatitis B
    • van der Poorten D, Prakoso E, Khoo TL, et al. 2007. Combination adefovir-lamivudine prevents emergence of adefovir resistance in lamivudine-resistant hepatitis B. J Gastroenterol Hepatol, 22:1500-5.
    • (2007) J Gastroenterol Hepatol , vol.22 , pp. 1500-1505
    • van der Poorten, D.1    Prakoso, E.2    Khoo, T.L.3
  • 53
    • 24044526915 scopus 로고    scopus 로고
    • Yang H, Qi X, Sabogal A, Miller M, Xiong S, Delaney WE 4th. 2005. Cross-resistance testing of next-generation nucleoside and nucleotide analogues against lamivudine-resistant HBV. Antivir Ther, 10:625-33.
    • Yang H, Qi X, Sabogal A, Miller M, Xiong S, Delaney WE 4th. 2005. Cross-resistance testing of next-generation nucleoside and nucleotide analogues against lamivudine-resistant HBV. Antivir Ther, 10:625-33.
  • 54
    • 33751287828 scopus 로고    scopus 로고
    • Efficacy of thymosin alpha-1 and interferon alpha in treatment of chronic viral hepatitis B: A randomized controlled study
    • You J, Zhuang L, Cheng HY, et al. 2006. Efficacy of thymosin alpha-1 and interferon alpha in treatment of chronic viral hepatitis B: a randomized controlled study. World J Gastroenterol, 12:6715-21.
    • (2006) World J Gastroenterol , vol.12 , pp. 6715-6721
    • You, J.1    Zhuang, L.2    Cheng, H.Y.3
  • 55
    • 33845675035 scopus 로고    scopus 로고
    • A randomized placebo-controlled, dose-finding study of oral LB80380 in HBeAg-positive patients with chronic hepatitis B
    • Yuen MF, Kim J, Kim CR, et al. 2006. A randomized placebo-controlled, dose-finding study of oral LB80380 in HBeAg-positive patients with chronic hepatitis B. Antivir Ther, 11:977-83.
    • (2006) Antivir Ther , vol.11 , pp. 977-983
    • Yuen, M.F.1    Kim, J.2    Kim, C.R.3


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