메뉴 건너뛰기




Volumn 36, Issue 10, 2008, Pages 2121-2129

Metabolic activity of cytochrome P450 isoforms in hepatocytes cryopreserved with wheat protein extract

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2C6; CYTOCHROME P450 2D2; CYTOCHROME P450 3A; CYTOCHROME P450 ISOENZYME; DIMETHYL SULFOXIDE; PLANT EXTRACT; UNCLASSIFIED DRUG; WHEAT PROTEIN EXTRACT;

EID: 52949083132     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.108.021162     Document Type: Article
Times cited : (16)

References (38)
  • 1
    • 0023787984 scopus 로고
    • Cryopreservation of isolated rat hepatocytes: A critical evaluation of freezing and thawing conditions
    • Chesné C and Guillouzo A (1988) Cryopreservation of isolated rat hepatocytes: a critical evaluation of freezing and thawing conditions. Cryobiology 25:323-330.
    • (1988) Cryobiology , vol.25 , pp. 323-330
    • Chesné, C.1    Guillouzo, A.2
  • 2
    • 0027218230 scopus 로고
    • Viability and function in primary culture of adult hepatocytes from various animal species and human beings after cryopreservation
    • Chesné C, Guyomard C, Fautrel A, Poullain MG, Fremond B, De Jong H, and Guillouzo A (1993) Viability and function in primary culture of adult hepatocytes from various animal species and human beings after cryopreservation. Hepatology 18:406-414.
    • (1993) Hepatology , vol.18 , pp. 406-414
    • Chesné, C.1    Guyomard, C.2    Fautrel, A.3    Poullain, M.G.4    Fremond, B.5    De Jong, H.6    Guillouzo, A.7
  • 3
    • 0027759816 scopus 로고
    • Cryopreservation of human adult hepatocytes for use in drug metabolism and toxicity studies
    • Coundouris JA, Grant MH, Engeset J, Petrie JC, and Hawksworth GM (1993) Cryopreservation of human adult hepatocytes for use in drug metabolism and toxicity studies. Xenobiotica 23:1399-1409.
    • (1993) Xenobiotica , vol.23 , pp. 1399-1409
    • Coundouris, J.A.1    Grant, M.H.2    Engeset, J.3    Petrie, J.C.4    Hawksworth, G.M.5
  • 4
    • 0031770592 scopus 로고    scopus 로고
    • Accumulation of an acidic dehydrin in the vicinity of the plasma membrane during cold acclimation of wheat
    • Danyluk J, Perron A, Houde M, Limin A, Fowler B, Benhamou N, and Sarhan F (1998) Accumulation of an acidic dehydrin in the vicinity of the plasma membrane during cold acclimation of wheat. Plant Cell 10:623-638.
    • (1998) Plant Cell , vol.10 , pp. 623-638
    • Danyluk, J.1    Perron, A.2    Houde, M.3    Limin, A.4    Fowler, B.5    Benhamou, N.6    Sarhan, F.7
  • 5
    • 0029828084 scopus 로고    scopus 로고
    • Increase of cytochrome P-450 1A and glutathione transferase transcripts in cultured hepatocytes from dogs, monkeys, and humans after cryopreservation
    • de Sousa G, Langouet S, Nicolas F, Lorenzon G, Placidi M, Rahmani R, and Guillouzo A (1996) Increase of cytochrome P-450 1A and glutathione transferase transcripts in cultured hepatocytes from dogs, monkeys, and humans after cryopreservation. Cell Biol Toxicol 12:351-358.
    • (1996) Cell Biol Toxicol , vol.12 , pp. 351-358
    • de Sousa, G.1    Langouet, S.2    Nicolas, F.3    Lorenzon, G.4    Placidi, M.5    Rahmani, R.6    Guillouzo, A.7
  • 6
    • 0027586305 scopus 로고
    • A method for the cryopreservation of liver parenchymal cells for studies of xenobiotics
    • Diener B, Utesch D, Beer N, Durk H, and Oesch F (1993) A method for the cryopreservation of liver parenchymal cells for studies of xenobiotics. Cryobiology 30:116-127.
    • (1993) Cryobiology , vol.30 , pp. 116-127
    • Diener, B.1    Utesch, D.2    Beer, N.3    Durk, H.4    Oesch, F.5
  • 8
    • 0022212644 scopus 로고
    • Studies on the maintenance of cytochromes P-450 and b5, monooxygenases and cytochrome reductases in primary cultures of rat hepatocytes
    • Grant MH, Melvin MA, Shaw P, Melvin WT, and Burke MD (1985) Studies on the maintenance of cytochromes P-450 and b5, monooxygenases and cytochrome reductases in primary cultures of rat hepatocytes. FEBS Lett 190:99-103.
    • (1985) FEBS Lett , vol.190 , pp. 99-103
    • Grant, M.H.1    Melvin, M.A.2    Shaw, P.3    Melvin, W.T.4    Burke, M.D.5
  • 9
    • 1642282158 scopus 로고    scopus 로고
    • First dose of potential new medicines to humans: How animals help
    • Greaves P, Williams A, and Eve M (2004) First dose of potential new medicines to humans: how animals help. Nat Rev Drug Discov 3:226-236.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 226-236
    • Greaves, P.1    Williams, A.2    Eve, M.3
  • 10
    • 0027343087 scopus 로고
    • Characterization of the in vitro hepatocyte model for toxicological evaluation: Repeated growth stimulation and glutathione response
    • Guillemette J, Marion M, Denizeau F, Fournier M, and Brousseau P (1993) Characterization of the in vitro hepatocyte model for toxicological evaluation: repeated growth stimulation and glutathione response. Biochem Cell Biol 71:7-13.
    • (1993) Biochem Cell Biol , vol.71 , pp. 7-13
    • Guillemette, J.1    Marion, M.2    Denizeau, F.3    Fournier, M.4    Brousseau, P.5
  • 11
    • 0033013025 scopus 로고    scopus 로고
    • Survival and function of isolated hepatocytes after cryopreservation
    • Guillouzo A, Rialland L, Fautrel A, and Guyomard C (1999) Survival and function of isolated hepatocytes after cryopreservation. Chem Biol Interact 121:7-16.
    • (1999) Chem Biol Interact , vol.121 , pp. 7-16
    • Guillouzo, A.1    Rialland, L.2    Fautrel, A.3    Guyomard, C.4
  • 12
    • 33750550103 scopus 로고    scopus 로고
    • Wheat extracts as an efficient cryoprotective agent for primary cultures of rat hepatocytes
    • Hamel F, Grondin M, Denizeau F, Averill-Bates DA, and Sarhan F (2006) Wheat extracts as an efficient cryoprotective agent for primary cultures of rat hepatocytes. Biotechnol Bioeng 95:661-670.
    • (2006) Biotechnol Bioeng , vol.95 , pp. 661-670
    • Hamel, F.1    Grondin, M.2    Denizeau, F.3    Averill-Bates, D.A.4    Sarhan, F.5
  • 14
    • 17744414112 scopus 로고    scopus 로고
    • Cryopreserved primary hepatocytes as a constantly available in vitro model for the evaluation of human and animal drug metabolism and enzyme induction
    • Hengstler JG, Utesch D, Steinberg P, Platt KL, Diener B, Ringel M, Swales N, Fischer T, Biefang K, Gerl M, et al. (2000b) Cryopreserved primary hepatocytes as a constantly available in vitro model for the evaluation of human and animal drug metabolism and enzyme induction. Drug Metab Rev 32:81-118.
    • (2000) Drug Metab Rev , vol.32 , pp. 81-118
    • Hengstler, J.G.1    Utesch, D.2    Steinberg, P.3    Platt, K.L.4    Diener, B.5    Ringel, M.6    Swales, N.7    Fischer, T.8    Biefang, K.9    Gerl, M.10
  • 15
    • 4043117632 scopus 로고    scopus 로고
    • Cryopreserved rat, dog and monkey hepatocytes: Measurement of drug metabolizing enzymes in suspensions and cultures
    • Hewitt NJ and Utesch D (2004) Cryopreserved rat, dog and monkey hepatocytes: measurement of drug metabolizing enzymes in suspensions and cultures. Hum Exp Toxicol 23:307-316.
    • (2004) Hum Exp Toxicol , vol.23 , pp. 307-316
    • Hewitt, N.J.1    Utesch, D.2
  • 17
    • 0032522873 scopus 로고    scopus 로고
    • Incidence of adverse drug reactions in hospitalized patients: A meta-analysis of prospective studies
    • Lazarou J, Pomeranz BH, and Corey PN (1998) Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA 279:1200-1205.
    • (1998) JAMA , vol.279 , pp. 1200-1205
    • Lazarou, J.1    Pomeranz, B.H.2    Corey, P.N.3
  • 18
    • 34247505574 scopus 로고    scopus 로고
    • Human hepatocytes: Isolation, cryopreservation and applications in drug development
    • Li AP (2007) Human hepatocytes: isolation, cryopreservation and applications in drug development. Chem Biol Interact 168:16-29.
    • (2007) Chem Biol Interact , vol.168 , pp. 16-29
    • Li, A.P.1
  • 20
    • 0030069147 scopus 로고    scopus 로고
    • Rat hepatocytes with elevated metallothionein expression are resistant to N-methyl-N′-nitro-N- nitrosoguanidine cytotoxicity
    • Moffatt P, Plaa GL, and Denizeau F (1996) Rat hepatocytes with elevated metallothionein expression are resistant to N-methyl-N′-nitro-N- nitrosoguanidine cytotoxicity. Toxicol Appl Pharmacol 136:200-207.
    • (1996) Toxicol Appl Pharmacol , vol.136 , pp. 200-207
    • Moffatt, P.1    Plaa, G.L.2    Denizeau, F.3
  • 22
    • 0031086009 scopus 로고    scopus 로고
    • A comparative study of the effect of freeze-thawing on peripheral and integral membrane proteins
    • Nardid O, Dyubko T, and Repina S (1997) A comparative study of the effect of freeze-thawing on peripheral and integral membrane proteins. Cryobiology 34:107-113.
    • (1997) Cryobiology , vol.34 , pp. 107-113
    • Nardid, O.1    Dyubko, T.2    Repina, S.3
  • 23
    • 9444231811 scopus 로고    scopus 로고
    • Use of a benzyloxy-substituted lactone cyclooxygenase-2 inhibitor as a selective fluorescent probe for CYP3A activity in primary cultured rat and human hepatocytes
    • Nicoll-Griffith DA, Chauret N, Houle R, Day SH, D'Antoni M, and Silva JM (2004) Use of a benzyloxy-substituted lactone cyclooxygenase-2 inhibitor as a selective fluorescent probe for CYP3A activity in primary cultured rat and human hepatocytes. Drug Metab Dispos 32:1509-1515.
    • (2004) Drug Metab Dispos , vol.32 , pp. 1509-1515
    • Nicoll-Griffith, D.A.1    Chauret, N.2    Houle, R.3    Day, S.H.4    D'Antoni, M.5    Silva, J.M.6
  • 24
    • 15444381338 scopus 로고    scopus 로고
    • Accelerated cytotoxicity mechanism screening using drug metabolising enzyme modulators
    • O'Brien PJ and Siraki AG (2005) Accelerated cytotoxicity mechanism screening using drug metabolising enzyme modulators. Curr Drug Metab 6:101-109.
    • (2005) Curr Drug Metab , vol.6 , pp. 101-109
    • O'Brien, P.J.1    Siraki, A.G.2
  • 26
    • 0025249973 scopus 로고
    • The maintenance of cytochrome P-450 in rat hepatocyte culture: Some applications of liver cell cultures to the study of drug metabolism, toxicity and the induction of the P-450 system
    • Paine AJ (1990) The maintenance of cytochrome P-450 in rat hepatocyte culture: some applications of liver cell cultures to the study of drug metabolism, toxicity and the induction of the P-450 system. Chem Biol Interact 74:1-31.
    • (1990) Chem Biol Interact , vol.74 , pp. 1-31
    • Paine, A.J.1
  • 27
    • 0027265192 scopus 로고
    • Flow cytometric analysis of the effects of tri-n-butyltin chloride on cytosolic free calcium and thiol levels in isolated rainbow trout hepatocytes
    • Reader S, Marion M, and Denizeau F (1993) Flow cytometric analysis of the effects of tri-n-butyltin chloride on cytosolic free calcium and thiol levels in isolated rainbow trout hepatocytes. Toxicology 80:117-129.
    • (1993) Toxicology , vol.80 , pp. 117-129
    • Reader, S.1    Marion, M.2    Denizeau, F.3
  • 28
    • 0033006714 scopus 로고    scopus 로고
    • Comparative effects of rifabutin and rifampicin on cytochromes P450 and UDP-glucuronosyl-transferases expression in fresh and cryopreserved human hepatocytes
    • Reinach B, de Sousa G, Dostert P, Ings R, Gugenheim J, and Rahmani R (1999) Comparative effects of rifabutin and rifampicin on cytochromes P450 and UDP-glucuronosyl-transferases expression in fresh and cryopreserved human hepatocytes. Chem Biol Interact 121:37-48.
    • (1999) Chem Biol Interact , vol.121 , pp. 37-48
    • Reinach, B.1    de Sousa, G.2    Dostert, P.3    Ings, R.4    Gugenheim, J.5    Rahmani, R.6
  • 29
    • 0017101039 scopus 로고
    • Preparation of isolated rat liver cells
    • Seglen PO (1976) Preparation of isolated rat liver cells. Methods Cell Biol 13:29-83.
    • (1976) Methods Cell Biol , vol.13 , pp. 29-83
    • Seglen, P.O.1
  • 30
    • 0027817015 scopus 로고
    • Cryopreservation and long-term storage of primary rat hepatocytes: Effects on substrate-specific cytochrome P450-dependent activities and unscheduled DNA synthesis
    • Shaddock JG, Snawder JE, and Casciano DA (1993) Cryopreservation and long-term storage of primary rat hepatocytes: effects on substrate-specific cytochrome P450-dependent activities and unscheduled DNA synthesis. Cell Biol Toxicol 9:345-357.
    • (1993) Cell Biol Toxicol , vol.9 , pp. 345-357
    • Shaddock, J.G.1    Snawder, J.E.2    Casciano, D.A.3
  • 31
    • 0033046389 scopus 로고    scopus 로고
    • Induction of cytochrome-P450 in cryopre-served rat and human hepatocytes
    • Silva JM, Day SH, and Nicoll-Griffith DA (1999) Induction of cytochrome-P450 in cryopre-served rat and human hepatocytes. Chem Biol Interact 121:49-63.
    • (1999) Chem Biol Interact , vol.121 , pp. 49-63
    • Silva, J.M.1    Day, S.H.2    Nicoll-Griffith, D.A.3
  • 32
    • 34447568267 scopus 로고    scopus 로고
    • Preclinical predictors of clinical safety: Opportunities for improvement
    • Sistare FD and DeGeorge JJ (2007) Preclinical predictors of clinical safety: opportunities for improvement. Clin Pharmacol Ther 82:210-214.
    • (2007) Clin Pharmacol Ther , vol.82 , pp. 210-214
    • Sistare, F.D.1    DeGeorge, J.J.2
  • 34
    • 33645694047 scopus 로고    scopus 로고
    • Analysis of the effects of cryopreservation on rat hepatocytes using SELDI-TOF mass spectrometry
    • Terry C, Bailey M, Mitry RR, Lehec SC, Dhawan A, and Hughes RD (2006a) Analysis of the effects of cryopreservation on rat hepatocytes using SELDI-TOF mass spectrometry. Cell Transplant 15:35-43.
    • (2006) Cell Transplant , vol.15 , pp. 35-43
    • Terry, C.1    Bailey, M.2    Mitry, R.R.3    Lehec, S.C.4    Dhawan, A.5    Hughes, R.D.6
  • 35
    • 33748459887 scopus 로고    scopus 로고
    • Cryopreservation of isolated human hepatocytes for transplantation: State of the art
    • Terry C, Dhawan A, Mitry RR, and Hughes RD (2006b) Cryopreservation of isolated human hepatocytes for transplantation: state of the art. Cryobiology 53:149-159.
    • (2006) Cryobiology , vol.53 , pp. 149-159
    • Terry, C.1    Dhawan, A.2    Mitry, R.R.3    Hughes, R.D.4
  • 36
    • 33645103494 scopus 로고    scopus 로고
    • Preincubation of rat and human hepatocytes with cytoprotectants prior to cryopreservation can improve viability and function upon thawing
    • Terry C, Dhawan A, Mitry RR, Lehec SC, and Hughes RD (2006c) Preincubation of rat and human hepatocytes with cytoprotectants prior to cryopreservation can improve viability and function upon thawing. Liver Transpl 12:165-177.
    • (2006) Liver Transpl , vol.12 , pp. 165-177
    • Terry, C.1    Dhawan, A.2    Mitry, R.R.3    Lehec, S.C.4    Hughes, R.D.5
  • 37
    • 33845409838 scopus 로고    scopus 로고
    • Evaluation of which reactive metabolite, if any, is responsible for a specific idiosyncratic reaction
    • Uetrecht J (2006) Evaluation of which reactive metabolite, if any, is responsible for a specific idiosyncratic reaction. Drug Metab Rev 38:745-753.
    • (2006) Drug Metab Rev , vol.38 , pp. 745-753
    • Uetrecht, J.1
  • 38
    • 0036910180 scopus 로고    scopus 로고
    • Anoikis: Roadblock to cell transplantation?
    • Zvibel I, Smets F, and Soriano H (2002) Anoikis: roadblock to cell transplantation? Cell Transplant 11:621-630.
    • (2002) Cell Transplant , vol.11 , pp. 621-630
    • Zvibel, I.1    Smets, F.2    Soriano, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.