Ofloxacin-associated retinopathy in rabbits: Role of oxidative stress

Human and Experimental Toxicology

Volumn 27, Issue 5, 2008, Pages 409-415

  Rampal, S ^a   Kaur, R ^a   Sethi, R ^a   Singh, O ^a   Sood, N ^a  

^a GURU ANGAD DEV VETERINARY AND ANIMAL SCIENCES UNIVERSITY   (India)

Author keywords

Ofloxacin; Oxidative stress; Rabbits; Retinopathy

Indexed keywords

CATALASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; OFLOXACIN; SUPEROXIDE DISMUTASE; ANTIINFECTIVE AGENT; GLUTATHIONE; OXIDOREDUCTASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; ENZYME ACTIVITY; GLOMERULUS; HISTOPATHOLOGY; LIPID PEROXIDATION; LIVER SINUSOID; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; RABBIT; RETINOPATHY; ANIMAL; CHEMICALLY INDUCED DISORDER; DOSE RESPONSE; DRUG EFFECT; KIDNEY; KIDNEY DISEASE; LIVER; LIVER DISEASE; METABOLISM; ORAL DRUG ADMINISTRATION; PATHOLOGY; RETINA; RETINA DEGENERATION;

ORYCTOLAGUS CUNICULUS;

ADMINISTRATION, ORAL; ANIMALS; ANTI-BACTERIAL AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; KIDNEY; KIDNEY DISEASES; LIPID PEROXIDATION; LIVER; LIVER DISEASES; OFLOXACIN; OXIDATION-REDUCTION; OXIDATIVE STRESS; OXIDOREDUCTASES; RABBITS; RETINA; RETINAL DEGENERATION;

EID: 52649174248     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327108092295     Document Type: Article

References (37)

1. Blondeau JM. Expanded activity and utility of the new fluoroquinolones: a review. Clin Ther 1999 ; 21: 3-40.
2. Food and Drug Administration. USA. FDA committee urges stronger warnings on Searles Maxaquin. Script 1993 ; 1810: 32-33.
3. Fernandez EB Cardenas AMG. The mechanism of photohaemolysis by photoproducts of nalidixic acid. J Photochem Photobiol B 1990 ; 4: 329-333.
4. Wada K Saniabadi AR Umemura K Takiguchi Y Nakashima M. UV-dependent quinolone-induced human erythrocyte membrane lipid peroxidation: studies on the phototoxicity of Y-26611, a new quinolone derivative. Pharmacol Toxicol 1994 ; 74: 240-243.
5. Shimoda K Yoshida M Wagai N Takayama S Kato M. Phototoxic lesions induced by quinolone antibacteraila agents in auricular skin and retina of albino mice. Toxicol Pathol 1993 ; 21: 554-561.
6. Wiebe V Pharm D Hamilton P. Flouoroquinolone-induced retinal degeneration in cats. J Am Vet Med Assoc 2002 ; 221: 1568-1571.
7. Benjamin MM. Outline of veterinary clinical pathology, 3rd ed. Ludhiana, India: Kalyani Publishers ; 1985.
8. Beutler E Duron O Kelly BM. Improved method for the determination of blood glutathione. J Lab Clin Med 1963 ; 61: 882-888.
9. Stocks J Dormandy TL. Autoxidation of human red cell lipids induced by hydrogen peroxide. Brit J Haematol 1971 ; 20: 95-111.
10. Hafeman DG Sunde RA Hoekstra WG. Effect of dietary selenium on erythrocyte and liver glutathione peroxidase in the rat. J Nutr 1974 ; 104: 580-587.
11. Carlberg I Mannervik B. Glutathione reductase. Methods Enzymol 1985 ; 113: 484-490.
12. Habig WH Pabst MJ Jakoby WB. Glutathione-S-transferase: The first enzymatic step in mercapturic acid formation. J Biol Chem 1974 ; 249: 7130-7139.
13. Marklund S Marklund G. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 1974 ; 47: 469-474.
14. Aebi HE. Catalase. In: HO Bergmeyer, (ed), Methods of enzymatic analysis, vol. III, New York: Academic press ; 1983. p. 273-386.
15. Snedecor GW Cochran WG. Statistical methods, 6th ed. Bombay: Allied Pacific ; 1967.
16. Luna LG. Manual of histologic staining methods of the armed forces institute of Pathology. New York: McGraw M U book company; 1968.
17. Gurbay A Gonthier B Daveloose D Favier A Hincal F. Microsomal metabolism of ciprofloxacin generates free radicals. Free Radic Biol Med 2001 ; 30: 1118-1121.
18. Asensi M Satre J Pallardo FV Lloret A Lehner M Asuncion JG. Ratio of reduced to oxidized glutathione as indicator of oxidative stress status and DNA damage. Methods Enzymol 1999 ; 299: 267-276.
19. Cantin AM North SL Hubbard RC Crystal RG. Normal alveolar epithelial lining fluid contains high levels of glutathione. J Appl Physiol 1987 ; 63: 152-157.
20. Ruffman R Wendel A. GSG resque by N-acetylcysteine. Klin Wochenschr 1991 ; 69: 857-862.
21. Thomas A Tocher J Edwards DI. Electrochemical characteristics of five quinolone drugs and their effect on DNA damage and repair in Escherichia coli. J Antimicrob Chemother 1990 ; 25: 502-522.
22. Shimoda K Nomura M Kato M. Effect of antioxidants, anti-inflammatory drugs, and histamine antagonists on sparfloxacin-induced phototoxicity in mice. Fundam Appl Toxicol 1996 ; 31: 133-140.
23. Shimoda K Kato M. Apoptotic photoreceptor cell death induced by quinolone phototoxicity in mice. Toxicol Lett 1999 ; 105: 9-15.
24. Cohen RG Raizman M Callina C Lahav M. Retinal safety of oral and topical ofloxacin in rabbits. J Ocul Pharmacol Ther 1997 ; 13: 369-379.
25. Gelatt KN Woerdt AV Ketring KL Andrew SE Brooks DE Biros DJ. Enrofloxacin-associated retinal degeneration in cats. Vet Ophthalmol 2001 ; 4: 99-106.
26. Petri WA. Antimicrobial agents: sulfonamides, trimethoprim, sulfamethoxazole, quinolones and agents for urinary tract infections. In: Goodman & Gilmans The Pharmacological Basis of Therapeutics. Edited by: Hardman, JG, Limbird, LE and Gilman, AG. Publ. McGraw Hill ; 2001. p. 1171-1188.
27. Nordman P. Cytotoxicity and uptake of pefloxacin, ciprofloxacin and ofloxacin in primary culture of rat hepatocytes. J Chemother 1989 ; 24: 355-363.
28. Zimpfer A Prpst A Mikuz G Vogel W Terracciano L Stadlmann S. Ciprofloxacin-induced acute liver injury: case report and review of literature. Virchows Arch 2004 ; 444: 87-89.
29. Bataille L Rahier J Geubel A. Delayed and prolonged cholestatic hepatitis with ductopenia after long-term ciprofloxacin therapy for Crohns disease. J Hepatol 2002 ; 37: 696-699.
30. Ostrovsky MA Ohkubo H Komura M. Intraocular pharmacokinetics of norfloxacin (NFLX) in pigmented animals. Chemotherapy (Tokyo) 1987 ; 42: 413-420.
31. Mitsui Y Ohkubo H Komuro M. Intraocular pharmacokinetics of norfloxacin (NFLX) in pigmented animals. Chemotherapy (Tokyo) 1994 ; 42: 413-420.
32. Wiechens B Neumann D Grammar JB. Retinal toxicity of liposome- incorporated and free ofloxacin after intravitreal injection in rabbit eyes. Int Ophthalmol 1998 ; 22: 133-143.
33. Shimoda K Okawara S Kato M. Phototoxic retinal degeneration and toxicokinetics of sitafloxacin, a quinolone antibacterial agent, in mice. Arch Toxicol 2001 ; 75: 395-399.
34. Umezawa N Arakane K Ryu A Mashiko S Hirobe M Nagano T. Participation of reactive oxygen species in phototoxicity induced by quinolone antibacterial agents. Arch Biochem Biophys 1997 ; 342: 275-281.
35. Devereaux QL Takahashi R Salvesen GS Reed JC. X-linked IAP is a direct inhibitor of cell-death proteases. Nature 1997 ; 388: 300-304.
36. Vander Heiden MG Chandel NS Williamson EK Schumacker PT Thompson CB. Bcl-xl regulates the membrane potential and volume homeostasis of mitochondria. Cell 1997 ; 91: 627-637.
37. Mignotte B Vayssiere JL. Mitochondria and apoptosis. Eur J Biochem 1998 ; 252: 1-15.