Phototoxic retinal degeneration and toxicokinetics of sitafloxacin, a quinolone antibacterial agent, in mice

Archives of Toxicology

Volumn 75, Issue 7, 2001, Pages 395-399

  Shimoda, Kohji ^a   Okawara, Satoshi ^a   Kato, Michiyuki ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

Phototoxicity; Quinolone; Retina; Sitafloxacin; Toxicokinetics

Indexed keywords

ANTIINFECTIVE AGENT; QUINOLONE DERIVATIVE; SITAFLOXACIN;

AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; EXTERNAL OTITIS; FEMALE; INFLAMMATION; MOUSE; NONHUMAN; PHOTOTOXICITY; PRIORITY JOURNAL; RETINA DEGENERATION; ULTRAVIOLET A RADIATION;

ANIMALS; ANTI-INFECTIVE AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FLUOROQUINOLONES; INJECTIONS, INTRAVENOUS; MICE; MICE, INBRED BALB C; PHOTORECEPTORS, VERTEBRATE; RETINAL DEGENERATION; TIME FACTORS; ULTRAVIOLET RAYS;

EID: 0034814368     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040100263     Document Type: Article

References (20)

1. High-performance liquid chromatographic determination of the new quinolone antibacterial agent DU-6859a in human serum and urine using solid-phase extraction with photolysis-fluorescence detection
2. Toxicity of the quinolones
3. The mechanism of photohemolysis by photoproducts of nalidixic acid
4. Phototoxicity from nalidixic acid: Oxygen-dependent photohemolysis
5. FDA committee urges stronger warnings on Searle's Maxaquin
6. In vitro phototoxic activities of new quinolone antibacterial agents: Lipid peroxidative potentials
7. Photodynamic lipid peroxidation in biological systems
8. The link between sunshine and phototoxicity of sparfloxacin
9. Antimicrobial activity of DU-6859a, a new potent fluoroquinolone, against clinical isolates
10. 2 production in Balb/c 3T3 mouse fibroblast cells by quinolone phototoxicity
11. Apoptotic photoreceptor cell death induced by quinolone phototoxicity in mice
12. Phototoxic lesions induced by quinolone antibacterial agents in auricular skin and retina of albino mice
13. Effect of antioxidants, anti-inflammatory drugs, and histamine antagonists on sparfloxacin-induced phototoxicity in mice
14. Stimulation of prostaglandin production by quinolone phototoxicity in Balb/c 3T3 mouse fibroblast cells in vitro
15. Possible relationship between phototoxicity and photodegradation of sitafloxacin, a quinolone antibacterial agent, in the auricular skin of albino mice
16. Clinical study on photosensitivity reactions due to lomefloxacin hydrochloride
17. Participation of reactive oxygen species in phototoxicity induced by quinolone antibacterial agents
18. UV-dependent quinolone-induced human erythrocyte membrane lipid peroxidation: Studies on the phototoxicity of Y-26611, a new quinolone derivative
19. Studies on experimental conditions for detecting phototoxic potentials of drugs in Balb/c mice
20. Three cases of photosensitive drug eruption induced by fleroxacin