Targeted chromosomal insertion of large DNA into the human genome by a fiber-modified high-capacity adenovirus-based vector system

PLoS ONE

Volumn 3, Issue 8, 2008, Pages

  Gonçalves, Manuel A F V ^a   Holkers, Maarten ^a   van Nierop, Gijsbert P ^a   Wieringa, Roeland ^a   Pau, Maria G ^b   de Vries, Antoine A F ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b CRUCELL HOLLAND BV   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; HELICASE; PARVOVIRUS VECTOR; RECOMBINASE; REP68 PROTEIN; REP78 PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; DNA REPLICATION; DNA STRUCTURE; DNA VECTOR; DUCHENNE MUSCULAR DYSTROPHY; ENZYME INHIBITION; FEMALE; FIBER; FLOW CYTOMETRY; GENE INSERTION; GENE SWITCHING; GENE TARGETING; GENE TRANSFER; GENETIC STABILITY; GENETIC TRANSDUCTION; HELA CELL; HUMAN; HUMAN CELL; HUMAN GENOME; HYBRIDIZATION; IMMUNOFLUORESCENCE MICROSCOPY; MYOBLAST; NONHUMAN; PROTEIN BINDING; PROTEIN FUNCTION; VIRAL GENE DELIVERY SYSTEM; WESTERN BLOTTING; ADENOVIRUS; ANIMAL; ANIMAL MODEL; CHROMOSOME; GENE THERAPY; GENE VECTOR; GENETICS; HUMAN CHROMOSOME; METHODOLOGY; TRANSPOSON;

ADENO-ASSOCIATED VIRUS; ADENOVIRIDAE; EUKARYOTA; MIRIDAE;

ADENOVIRIDAE; ANIMALS; CHROMOSOMES; CHROMOSOMES, HUMAN; DNA REPLICATION; DNA TRANSPOSABLE ELEMENTS; GENE THERAPY; GENETIC VECTORS; GENOME, HUMAN; HUMANS; MODELS, ANIMAL;

EID: 52649167362     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0003084     Document Type: Article

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