Optimisation of sampling windows design for population pharmacokinetic experiments

Journal of Pharmacokinetics and Pharmacodynamics

Volumn 35, Issue 4, 2008, Pages 465-482

  Ogungbenro, Kayode ^a   Aarons, Leon ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

D optimality; Fisherinformation matrix; Nonlinear mixed effects; Optimal design; Pharmacokinetics; Sampling windows

Indexed keywords

DRUG;

ARTICLE; CALCULATION; COMPARTMENT MODEL; CONTROL STRATEGY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DISTRIBUTION; HUMAN; MATHEMATICAL ANALYSIS; NONLINEAR SYSTEM; PARAMETER; PHARMACOKINETICS; POPULATION PHARMACOKINETIC SAMPLING WINDOWS DESIGN; POPULATION RESEARCH; POPULATION STRUCTURE; PRIORITY JOURNAL; PROCESS OPTIMIZATION; SAMPLING; TIME;

ALGORITHMS; DATA INTERPRETATION, STATISTICAL; INJECTIONS, INTRAVENOUS; INTESTINAL ABSORPTION; MONTE CARLO METHOD; MULTICENTER STUDIES AS TOPIC; PHARMACOKINETICS; POPULATION; RESEARCH DESIGN; SAMPLING STUDIES;

EID: 52549124876     PISSN: 1567567X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10928-008-9097-1     Document Type: Article

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