Optimization of Individual and Population Designs using Splus

Journal of Pharmacokinetics and Pharmacodynamics

Volumn 30, Issue 6, 2003, Pages 417-443

  Retout, Sylvie ^a   Mentré, France ^a  

^a BICHAT HOSPITAL   (France)

Author keywords

D optimality; Designs optimization; Fisher information matrix; Nonlinear mixed effects models; Pharmacokinetics; Simplex algorithm

Indexed keywords

ENOXAPARIN;

ALGORITHM; ANALYTIC METHOD; ANALYTICAL ERROR; ARTICLE; COMPUTER ANALYSIS; COMPUTER PROGRAM; CONTROLLED STUDY; DRUG DESIGN; EVALUATION; HUMAN; PARAMETER; PERFORMANCE; PRIORITY JOURNAL; SAMPLING; STATISTICAL ANALYSIS; STRUCTURE ANALYSIS;

ALGORITHMS; COMPUTER SIMULATION; DATA INTERPRETATION, STATISTICAL; DRUG EVALUATION; MODELS, BIOLOGICAL; PHARMACOKINETICS; RESEARCH DESIGN;

EID: 1242269754     PISSN: 1567567X     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:JOPA.0000013000.59346.9a     Document Type: Article

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