Expression of cTnI-R145G affects shortening properties of adult rat cardiomyocytes

Pflugers Archiv European Journal of Physiology

Volumn 457, Issue 1, 2008, Pages 17-24

  Reis, Stephanie ^a   Littwitz, Christoph ^b   Preilowski, Sebastian ^a   Mügge, Andreas ^a   Stienen, Ger J M ^c   Pott, Lutz ^b   Jaquet, Kornelia ^a  

^a ST JOSEF HOSPITAL   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Adrenergic; Cardiomyocyte; Contraction; Electrical stimulation; Forskolin; Hypertrophy; Mutation; Rat; Shortening velocity; Stimulation

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; AMINO ACID; FORSKOLIN; ISOPRENALINE; RECEPTOR SUBTYPE; TROPONIN I;

ADENOVIRUS; ADRENERGIC SYSTEM; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HEART MUSCLE CELL; MUSCLE ISOTONIC CONTRACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SARCOMERE; VIRUS RECOMBINANT; WILD TYPE;

ADENOVIRIDAE; ADRENERGIC BETA-AGONISTS; AMINO ACID SUBSTITUTION; ANIMALS; BLOTTING, WESTERN; CELL SEPARATION; ELECTRIC STIMULATION; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC VECTORS; HEART VENTRICLES; HUMANS; ISOTONIC CONTRACTION; MUTATION; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; RATS; RATS, INBRED WKY; TROPONIN I;

EID: 52549092440     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-008-0487-4     Document Type: Article

References (32)

1. BJ Maron JM Gardin JM Flack SS Gidding D Bild 1995 Prevalence of hypertrophic cardiomyopathy in a general population of young adults: echocardiographic analysis of 4111 subjects in the CARDIA study Circulation 92 785 789
2. BJ Maron 2002 Hypertrophic cardiomyopathy Circulation 106 2419 2421
3. AV Gomes JD Potter 2004 Molecular and cellular aspects of troponin cardiomyopathies Ann NY Acad Sci 1015 214 224 Review
4. AV Gomes JD Potter 2004 Cellular and molecular aspects of familial hypertrophic cardiomyopathy caused by mutations in the cardiac troponin I gene Mol Cell Biochem 263 99 114
5. J Layland RJ Solaro AM Shah 2005 Regulation of cardiac contractile function by troponin I phosphorylation Cardiovasc Res 66 12 21
6. O-E Brodde H Bruck K Leineweber 2006 Cardiac adrenoceptors: physiological and pathophysiological relevance J Pharmacol Sci 100 323 337 Review
7. K Mittmann K Jaquet LMG Heilmeyer Jr 1990 A common motif of two adjacent phosphoserines in bovine, rabbit and human cardiac troponin I FEBS Lett 273 41 45
8. 2+ affinity of cardiac troponin C J Biol Chem 270 30773 30780
9. SU Reiffert K Jaquet LMG Heilmeyer Jr MD Ritchie MA Geeves 1996 Bisphosphorylation of cardiac troponin I modulates the Ca(2+)-dependent binding of myosin subfragment S1 to reconstituted thin filaments FEBS Lett 384 43 47
10. R Zhang J Zhao A Mandveno JD Potter 1995 Cardiac troponin I phosphorylation increases the rate of cardiac muscle relaxation Circ Res 76 1028 1035
11. JC Kentish DT McCloskey J Layland S Palmer JM Leiden AF Martin RJ Solaro 2001 Phosphorylation of troponin I by protein kinase A accelerates relaxation and cross bridge cycle kinetics in mouse ventricular muscle Circ Res 88 1059 1065
12. S Yasuda P Couto S Sadayappan J Robbins JM Metzger 2007 Cardiac transgenic and gene transfer strategies converge to support an important role for troponin I in regulating relaxation in cardiac myocytes Circ Res 101 377 386
13. TC He S Zhou LT da Costa J Yu KW Kinzler B Vogelstein 1998 A simplified system for generating recombinant adenoviruses Proc Natl Acad Sci U S A 95 2509 2514
14. M Bünemann B Brandts L Pott 1997 In vivo downregulation of M2 receptors revealed by measurement of muscarinic K+ current in cultured guinea-pig atrial myocytes J Physiol 501 Pt 3 549 554
15. 2-adrenoceptors in hypertrophic and apoptotic effects of noradrenaline and adrenaline in adult ventricular cardiomyocytes Naunyn Schmiedebergs Arch Pharmacol 367 592 599
16. CC Lim MH Helmes DB Sawyer M Jain R Liao 2001 High-through-put assessment of calcium sensitivity in skinned cardiac myocytes Am J Physiol Heart Circ Physiol 281 H969 974
17. VJA Schouten JK van Deen P De Tombe AA Verveen 1987 Force-interval relationship in heart muscle of mammals Biophys J 51 13 26
18. K Tiemann D Weyer PC Djoufack A Ghanem T Lewalter U Dreiner R Meyer C Grohe KB Fink 2003 Increasing myocardial contraction and blood pressure in C57BL/6 mice during early postnatal development Am J Physiol Heart Circ Physiol 284 H464 H474
19. A Schmidtmann C Lindow S Villard A Heuser A Mügge R Geßner C Granier K Jaquet 2005 Cardiac troponin C-L29Q related to hypertrophic cardiomyopathy, hinders the transduction of the protein kinase A dependent phosphorylation signal from cardiac troponin I to C FEBS J 272 6087 6097
20. MV Westfall FP Albayya II Turner JM Metzger 2000 Chimera analysis of troponin I domains that influence Ca2+-activated myofilament tension in adult cardiac myocytes Circ Res 86 470 477
21. AF Martin 1981 Turnover of cardiac troponin subunits. Kinetic evidence of a precursor pool of cardiac troponin I J Biol Chem 256 964 968
22. S Nishimura S Nagai M Sata M Katoh H Yamashita Y Saeki R Nagai S Sugiura 2006 Expression of green fluorescent protein impairs the force-generating ability of isolated rat ventricular cardiomyocytes Mol Cell Biochem 286 59 65
23. JE Frampton SM Harrison MR Bovett CH Orchard 1991 Ca2+ and Na+ in rat myocytes showing different force-frequency relationships Am J Physiol 261 C739 C750
24. NR Alpert G Hasenfuss BJ Leavitt FP Ittleman B Pieske LA Mulieri 2000 A mechanistic analysis of reduced mechanical performance in human heart failure Jpn Heart J 41 103 115
25. DM Bers 2000 Calcium fluxes involved in control of cardiac myocytes contraction Circ Res 87 275 281
26. RR Lamberts N Hamdani TW Soekhoe NM Boontje R Zaremba LA Walker P de Tombe J van der Velden G Stienen 2007 Frequency dependent myofilament Ca2+-desensitization in failing rat myocardium J Physiol 582 Pt2 695 709
27. DM Bers 1985 Calcium influx and sarcoplasmatic reticulum calcium release in cardiac muscle activation during post-rest recovery Am J Physiol 248 H366 H381
28. B Pieske M Sütterlin S Schmidt-Schweda K Minami M Meyer M Olschewski C Holubarsch H Just G Hasenfuss 1996 Diminished post-rest potentiation of contractile force in human dilated cardiomyopathy J Clin Invest 98 764 776
29. IR Wendt CL Gibbs G Kotsanas IR Young 1991 Altered pattern of post rest contraction in hypertrophied rabbit ventricle Heart Vessels 6 143 149
30. M Kruger S Zittrich C Redwood N Blaudeck J James J Robbins G Pfitzer R Stehle 2005 Effects of the mutation R145G in human cardiac troponin I on the kinetics of the contraction-relaxation cycle in isolated cardiac myofibrils J Physiol 564 347 357
31. J James Y Zhang H Osinska A Sanbe R Klevitsky TE Hewett J Robbins 2000 Transgenic modelling of a cardiac troponin I mutation linked to familial cardiac hypertrophy Circ Res 87 805 811
32. Y Deng A Schmidtmann A Redlich B Westerdorf K Jaquet R Thieleczek 2001 Effects of phosphorylation and mutation R145G on human cardiac troponin I function Biochemistry 40 14593 14602