Synthesis of GPIbβ with novel transmembrane and cytoplasmic sequences in a Bernard-Soulier patient resulting in GPIb-defective signaling in CHO cells

Journal of Thrombosis and Haemostasis

Volumn 4, Issue 1, 2006, Pages 217-228

  Strassel, C ^a   David, T ^a   Eckly, A ^a   Baas, M J ^a   Moog, S ^a   Ravanat, C ^a   Trzeciak, M C ^b   Vinciguerra, C ^b   Cazenave, J P ^a   Gachet, C ^a   Lanza, François ^a  

^a INSERM   (France)

^b EDOUARD HERRIOT HOSPITAL   (France)

Author keywords

Bernard Soulier; GPIb ; Intracellular domain

Indexed keywords

BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 9; GLYCOPROTEIN IB; GLYCOPROTEIN IB ALPHA; GUANINE; MUTANT PROTEIN; PROTEIN SUBUNIT; RISTOCETIN; VON WILLEBRAND FACTOR; PEPTIDE FRAGMENT; THROMBIN RECEPTOR;

ANIMAL CELL; ARTICLE; BERNARD SOULIER DISEASE; CASE REPORT; CELL LYSATE; CELL SURFACE; CHO CELL; COMPLEX FORMATION; CONTROLLED STUDY; FEMALE; GENE INSERTION; GENE SEQUENCE; GENETIC TRANSFECTION; GLYCOPROTEIN SYNTHESIS; HUMAN; IMMUNOPRECIPITATION; IMMUNOREACTIVITY; MOROCCO; NONHUMAN; NUCLEOTIDE SEQUENCE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; RIBOSOMAL FRAMESHIFTING; SIGNAL TRANSDUCTION; THROMBOCYTE AGGLUTINATION; THROMBOCYTOPENIA; WESTERN BLOTTING; AMINO ACID SEQUENCE; ANIMAL; BLOOD; CELL MEMBRANE; CELL SHAPE; CYTOPLASM; FRAMESHIFT MUTATION; GENETICS; HAMSTER; METABOLISM; PATHOLOGY; THROMBOCYTE;

AMINO ACID SEQUENCE; ANIMALS; BERNARD-SOULIER SYNDROME; BLOOD PLATELETS; CELL MEMBRANE; CELL SHAPE; CHILD, PRESCHOOL; CHO CELLS; CRICETINAE; CYTOPLASM; FEMALE; FRAMESHIFT MUTATION; HUMANS; PEPTIDE FRAGMENTS; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; SIGNAL TRANSDUCTION; THROMBOCYTOPENIA; TRANSFECTION; VON WILLEBRAND FACTOR;

EID: 33644859940     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2005.01654.x     Document Type: Article

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