Applying extrusion to pharmaceutical formulation design

Technical Papers, Regional Technical Conference - Society of Plastics Engineers

Volumn 3, Issue , 2008, Pages 1445-1449

  McKelvey, Craig A ^a   Schenck, Luke ^a   Lowinger, Michael ^a   Troup, Gregory M ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Drug; Extrusion; Insoluble; Pharmaceutical; Solid dispersion; Solid solution; Solvent casting

Indexed keywords

APPLICATION EXAMPLES; CHEMICAL COMPOSITIONS; DRUG; EXPERIMENTAL DATA; EXTRUDATE; INSOLUBLE; NEAR INFRA-RED; PHARMACEUTICAL; PHARMACEUTICAL FORMULATIONS; POLYMER POWDERS; PREDICTIVE MODELING; PROCESS DEVELOPMENTS; RESIDENCE-TIME DISTRIBUTIONS; SOLID DISPERSION; SOLID SOLUTION; SOLVENT CASTING; SOLVENT-BASED; TECHNICAL CONFERENCES;

ELASTOMERS; EXTRUSION; FORMING; PLASTICITY; POLYMERS; PROCESS ENGINEERING; SOLID SOLUTIONS;

PLASTIC PRODUCTS;

EID: 52349090972     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (9)

1. C.A. Lipinski, F. Lombardo, B.W. Dominy, P.J. Feeney, Advanced Drug Delivery Reviews, 23, 3 (1997).
2. C.A. Lipinski, Journal of Pharmacological and Toxicological Methods, 44, 235 (2000).
3. S. Stegemann, F. Leveiller, D. Franchi, H. de Jong, H. Linden, European Journal of the Pharmaceutical Sciences, 31, 249 (2007).
4. A.T.M. Serajuddin, Journal of Pharmaceutical Sciences, 88:10, 1058 (1999).
5. K. Sekiguchi, N. Obi, Chem. Pharm. Bull., 9, 866 (1961).
6. M. J. Mollan Jr., Arden House Presentation (2005).
7. J. Breitenbach, American Journal of Drug Delivery, 4:2, 61 (2006).
8. H.-H. Goertz, R.G. Klimesch, K. Laemmerhirt, S. Lang, A. Sanner, R. Spengler, U.S. Patent 4,801,460 (1989).
9. D.B. Todd, SPE-ANTEC Tech. Papers, 43, 116 (1997).