IVIVC of controlled release formulations: Physiological-dynamical reasons for their failure

Journal of Controlled Release

Volumn 129, Issue 2, 2008, Pages 76-78

  Dokoumetzidis, A ^a   Macheras, P ^b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF ATHENS   (Greece)

Author keywords

Anomalous diffusion; GI variability; IVIVC

Indexed keywords

BILE SALT; CHOLESTEROL; FATTY ACID; PHOSPHOLIPID; POLYMER;

CONTROLLED DRUG RELEASE; CORRELATION ANALYSIS; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG DOSAGE FORM; DRUG FORMULATION; DRUG METABOLISM; DRUG POTENTIATION; DRUG SOLUBILITY; GALLBLADDER CONTRACTION; GASTROINTESTINAL ABSORPTION; HYDRODYNAMICS; IN VITRO IN VIVO CORRELATION; IN VITRO STUDY; IN VIVO STUDY; INTESTINE FLUID; INTESTINE MOTILITY; MONTE CARLO METHOD; NONLINEAR SYSTEM; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SHORT SURVEY; STOMACH JUICE; STRUCTURE ACTIVITY RELATION;

ANIMALS; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DIFFUSION; DRUG COMPOUNDING; FRACTALS; GASTROINTESTINAL TRACT; HUMANS; KINETICS; MODELS, BIOLOGICAL; MODELS, CHEMICAL; NONLINEAR DYNAMICS; PHARMACOKINETICS; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL;

EID: 52249112060     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2008.04.005     Document Type: Short Survey

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