Probabilistic methods for drug dissolution. Part 2. Modelling a soluble binary drug delivery system dissolving in vitro

Simulation Modelling Practice and Theory

Volumn 14, Issue 7, 2006, Pages 857-873

  Barat, Ana ^a   Ruskin, Heather J ^a   Crane, Martin ^a  

^a DUBLIN CITY UNIVERSITY   (Ireland)

Author keywords

Cellular automata; Design and experiment; Dissolution; Drug delivery systems; Modelling; Monte Carlo; Multicomponent soluble compacts

Indexed keywords

DISSOLUTION; MASS TRANSFER; MATHEMATICAL MODELS; MONTE CARLO METHODS; PHASE INTERFACES;

CELLULAR AUTOMATA; DRUG DELIVERY SYSTEMS; MULTICOMPONENT SOLUBLE COMPACTS;

DRUG DOSAGE;

EID: 33749081165     PISSN: 1569190X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.simpat.2006.03.003     Document Type: Article

References (25)

1. United States Pharmacopoeia. Available from: . Access date: 16/06/2004.
2. Chen X., Chen W., Hical A.H., Shen B.-C., and Fan L.T. Stochastic modeling of controlled-drug release. Biochemical Engineering Journal 2 (1998) 161-177
3. Chopard B., and Droz M. Cellular Automata Modeling of Physical Systems (1998), Cambridge University Press
4. Costa P., and Lobo J.M.S. Modeling and comparison of dissolution profiles. European Journal of Pharmaceutical Sciences 13 (2001) 123-133
5. Cranck J. The Mathematics of Diffusion (1975), Clarendon Press, Oxford
6. Crane M., Crane L., Healy A.M., Corrigan O.I., Gallagher K.M., and McCarthy L. A Pohlhausen solution for the mass flux from a multi-layered compact in the USP drug dissolution apparatus. Simulation Modelling Practice and Theory (SIMPAT) (2004)
7. Crane M., Hurley N.J., Crane L., Healy A.M., Corrigan O.I., Gallagher K.M., and McCarthy L.G. Simulation of the USP drug delivery problem using CFD: experimental, numerical and mathematical aspects. Simulation Modelling Practice and Theory (SIMPAT) (2004) 12
8. Göpferich A. Erosion of composite polymer matrices. Biomaterials 18 (1997) 397-403
9. Göpferich A., and Langer R. Modeling monomer release from bioerodible polymers. Journal of Controlled Release 33 (1995) 55-69
10. A.M. Healy, Investigations of the dissolution mechanisms of acidic drug-excipient compacts. Ph.D. Thesis, University of Dublin, Trinity College, 1995.
11. Healy A.M., and Corrigan O.I. Predicting the dissolution rate of ibuprofen acidic excipient compressed mixtures in reactive media. International Journal of Pharmaceutics 84 (1992) 167-173
12. Healy A.M., and Corrigan O.I. The influence of excipient particle size, solubility and acid strength on the dissolution of an acidic drug from two-component compacts. International Journal of Pharmaceutics 143 (1996) 211-221
13. Kalampokis A., Argyrakis P., and Macheras P. Heterogeneous tube model for the study of small intestinal transit flow. Pharmaceutical Research 16 1 (1999)
14. Kosmidis K., and Argyrakis P. Fractal kinetics in drug release from finite fractal matrices. Journal of Chemical Physics 119 12 (2000)
15. Kosmidis K., Rinaki E., Argyrakis P., and Macheras P. Analysis of case ii drug transport with radial and axial release from cylinders. International Journal of Pharmaceutics (2003) 254
16. Landau D.P., and Binder K. Monte Carlo Simulations in Statistical Physics (2000), Cambridge University Press
17. McCarthy L., Kosiol C., Healy A., Bradley G., Sexton J., and Corrigan O. Simulating the hydrodynamic conditions in the United States Pharmacopeia paddle dissolution apparatus. AAPS PharmSciTech 4 2 (2003) 109-115
18. Narasimhan B. Mathematical models describing polymer dissolution: consequences for drug delivery. Advanced Drug Delivery Reviews 48 (2001) 195-210
19. Prandtl L., and Tietjens O. Applied Hydro- and Aeromechanics (1957), Dover Publications New York Paperback Chapter IV
20. Ramtoola Z., and Corrigan O.I. Dissolution characteristics of benzoic acid and salicylic acid mixtures in reactive media. Drug Development and Industrial Pharmacy 13 (1987) 9-11
21. Schlichting H. Boundary-Layer Theory. seventh ed. (1979), McGraw-Hill, New York; London Chapter XII
22. Siepmann J., and Göpferich A. Mathematical modeling of bioerodible polymeric drug delivery systems. Advanced Drug Delivery Reviews 48 (2001) 229-247
23. Siepmann J., and Peppas N.A. Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC). Advanced Drug Delivery Reviews 48 (2001) 139-157
24. Sun Y., Peng Y., Chen Y., and Shukla A.J. Application of artificial neural networks in the design of controlled release drug delivery systems. Advanced Drug Delivery Reviews 55 (2003) 1201-1215 Preface
25. Zygourakis K., and Markenscoff P.A. Computer-aided design of bioerodible devices with optimal release characteristics: a cellular automata approach. Biomaterials 17 (1996) 125-135