Low-dose hypersensitive γH2AX response and infrequent apoptosis in epidermis from radiotherapy patients

Radiotherapy and Oncology

Volumn 88, Issue 3, 2008, Pages 388-397

  Simonsson, Martin ^a   Qvarnström, Fredrik ^a   Nyman, Jan ^b   Johansson, Karl Axel ^b   Garmo, Hans ^c   Turesson, Ingela ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^c UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

H2AX; Apoptosis; Digital image analysis; DNA damage; DNA repair; Double strand breaks; DSB; Epidermis; Foci; Hypersensitivity; Normal tissue; Parp 1

Indexed keywords

HISTONE GAMMA H2AX; HISTONE H2AX; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER RADIOTHERAPY; CLINICAL ARTICLE; CONTROLLED STUDY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; EPIDERMIS; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; PRIORITY JOURNAL; PROSTATE CANCER; RADIATION DOSE FRACTIONATION; SKIN BIOPSY; TREATMENT RESPONSE;

APOPTOSIS; BIOPSY; CELL NUCLEUS; DNA DAMAGE; DNA REPAIR; DOSE FRACTIONATION; DOSE-RESPONSE RELATIONSHIP, RADIATION; EPIDERMIS; HISTONES; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; MALE; PROSTATIC NEOPLASMS; RADIATION TOLERANCE; RADIOTHERAPY DOSAGE;

EID: 52249090889     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.radonc.2008.04.017     Document Type: Article

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