NFIB rearrangement in superficial, retroperitoneal, and colonic lipomas with aberrations involving chromosome band 9p22

Genes Chromosomes and Cancer

Volumn 47, Issue 11, 2008, Pages 971-977

  Italiano, Antoine ^a,b   Ebran, Nathalie ^a,b   Attias, Rita ^a,b   Chevallier, Anne ^a   Monticelli, Isabelle ^c   Mainguené, Claire ^c   Benchimol, Daniel ^a   Pedeutour, Florence ^a,b,d  

^a UNIVERSITY HOSPITAL OF NICE   (France)

^b CNRS   (France)

^c CENTRE HOSPITALIER PRINCESSE GRACE   (Monaco)

^d UNIVERSITÉ CÔTE D'AZUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEAR FACTOR I;

ARTICLE; CHROMOSOME 9P; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHROMOSOME BAND; CLINICAL ARTICLE; COLON TUMOR; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENE FUSION; GENE REARRANGEMENT; HMGA2 GENE; HUMAN; LIPOMA; MOLECULAR GENETICS; NFIB GENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RETROPERITONEAL TUMOR; SUPERFICIAL CANCER;

ADULT; AGED; BASE SEQUENCE; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 9; COLONIC NEOPLASMS; FEMALE; HUMANS; KARYOTYPING; LIPOMA; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; NFI TRANSCRIPTION FACTORS; RETROPERITONEAL NEOPLASMS;

EID: 52249084731     PISSN: 10452257     EISSN: 10982264     Source Type: Journal    
DOI: 10.1002/gcc.20602     Document Type: Article

References (31)

1. Arlt MF, Durkin SG, Ragland RL, Glover TW. 2006. Common fragile sites as targets for chromosome rearrangements. DNA Repair 5:1126-1135.
2. Ashar HR, Fejzo MS, Tkachenko A, Zhou X, Fletcher JA, Weremowicz S, Morton CC, Chada K. 1995. Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains. Cell 82:57-65.
3. Bartuma H, Hallor KH, Panagopoulos I, Collin A, Rydholm A, Gustafson P, Bauer HC, Brosjö O, Domanski HA, Mandahl N, Mertens F. 2007. Assessment of the clinical and molecular impact of different cytogenetic subgroups in a series of 272 lipomas with abnormal karyotype. Genes Chromosomes Cancer 46:594-606.
4. Broberg K, Zhang M, Strömbeck B, Isaksson M, Nilsson M, Mertens F, Mandahl N, Panagopoulos I. 2002. Fusion of RDCI with HMGA2 in lipomas as the result of chromosome aberrations involving 2q35-37 and 12q13-15. Int J Oncol 21:321-526.
5. Fedele M, Berlingieri MT, Scala S, Ghiariotti L, Viglietto G, Rippel V, Bullerdick J, Santoro M, Fusco A. 1998. Truncated and chimeric HMGI-C genes induce neoplastic transformation of NIH3T3 murine fibroblasts. Oncogene 17:413-418.
6. Fedele M, Battista S, Manfioletti G, Croce CM, Giancotti V, Fusco A. 2001. Role of the high mobility group A proteins in human lipomas. Carcinogenesis 22:1583-1591.
7. Fletcher G, Unni K, Mertens F. 2002. World Health Classification of Tumors. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IARC Press.
8. Foa C, Mainguené C, Dupré F, Coindre JM, Huguet C, Kober C, Pedeutour F. 2002. Rearrangements involving chromosomes 1 and 8 in a retroperitoneal lipoma. Cancer Genet Cytogenet 133:156-159.
9. Geurts JM, Schoenmakers EF, Röijer E, Aström AK, Stenman G, van de Ven WJ. 1998. Identification of NFIB as recurrent translocation partner gene of HMGIC in pleomorphic adenomas. Oncogene 16:865-872.
10. Goodwin G. 1998. The high mobility group protein. HMGI-C. Int J Biochem Cell Biol 30:761-766.
11. Gronostajski RM. 2000. Roles of the NFI/GTF gene family in transcription and development. Gene 249:31-45.
12. Han W, Jung EM, Cho J, Lee JW, Hwang KT, Yang SJ, Kang JJ, Bae JY, Jeon YK, Park IA, Nicolau M, Jeffrey SS, Noh DY. 2008. DNA copy number alterations and expression of relevant genes in triple-negative breast cancer. Genes Chromosomes Cancer 47:490-499.
13. Hatano H, Morita T, Ogose A, Hotta T, Kobayashi H, Segawa W, Uchiyama T, Takenouchi T, Sato T. 2008. Clinicopathological features of lipomas with gene fusions involving HMGA2. Anticancer Res 28:535-538.
14. Italiano A, Bianchini L, Keslair F, Bonnafous S, Cardot-Leccia N, Coindre JM, Dumollard JM, Hofman P, Leroux A, Mainguené C, Peyrottes I, Ranehere-Vince D, Terrier P, Tran A, Gual P, Pedeutour F. 2008. HMGA2 is the partnet of MDM2 in well-differentiated and dedifferentiated liposarcomas whereas CDK4 belongs to a distinct inconsistent amplicon. Int J Cancer 122:2233-2241.
15. Kataoka S, Yamada H, Hoshi N, Kudo M, Hareyama H, Sakuragi N, Fujimoto S. 2003. Cytogenetic analysis of uterine leiomyoma: The size, histopathology and GnRHa-response in relation to chromosome karyotype. Eur J Obstet Gynecol Reprod Biol 110:58-62.
16. Kazmierczak B, Dal Cin P, Wanschura S, Borrmann L, Fusco A, Van den Berghe H, Bullerdick J. 1998. HMGIY is the target of 6p21 rearrangements in various benign mesenchymal tumors. Genes Chromosomes Cancer 23:79-85.
17. Kiechle-Schwarz M, Sreekantaiah C, Berger CS, Pedron S, Medchill MT, Surti L, Sandberg AA. 1991. Nonrandom cytogenetic changes in leiomyomas of the female genitourinary tract. A report of 35 cases. Cancer Genet Cytogenet 53:125-136.
18. Kim HY, Gladyshev VN. 2004. Methionine sulfoxide reduction in mammals: Characterization of methionine-R-sulfoxide reductases. Mol Biol Cell 15:1055-1064.
19. Kralovics R, Guan Y, Prehal JT. 2002. Acquired uniparental disomy of chromosome 9p is a frequent stem cell defect in polycythemia vera. Exp Hematol 30:229-236.
20. Lee YS, Dutta A. 2007. The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes Dev 21:1025-1030.
21. Mayr C, Hemann MT, Bartel DP. 2007. Disrupting the pairing between let-7 and HMGA2 enhances oncogenic transformation. Science 315:1576-1579.
22. Medeiros F, Wang X, Erickson-Johnson M, Nascimento A, Oliveira A. 2007. HMGA1 rearrangements occur in a small subset of spindle cell lipomas. Virchows Arch 451:578 (abstract PP4-272).
23. Nilsson M, Panagopoulos I, Mertens F, Mandahl N. 2005. Fusion of the HMGA2 and NFIB genes in lipoma. Virchows Arch 447:855-858.
24. Nilsson M, Mertens F, Höglund M, Mandahl N, Panagopoulos I. 2006. Truncation and fusion of HMGA2 in lipomas with rearrangements of 5q32->q33 and 12q14->q15. Cytogenet Genome Res 112:60-66.
25. Pedeutour F, Italiano A. 2008. Adipose tumors. In: Schwab ,M, editor. Encyclopedia of Cancer, 2nd ed. Berlin: Springer-Verlag.
26. Petit MM, Mols R, Schoenmakers EF, Mandahl N, Van de Ven WJ. 1996. LPP, the preferred fusion partner gene of HMGIC in lipomas, is a novel member of the LIM protein gene family. Genomics 36:118-129.
27. Sawinska M, Schmitt JG, Sagulenko E, Westermann F, Schwab M, Savelyeva L. 2007. Novel aphidicolin-inducible common fragile site FRA9G maps to 9p22.2, within the C9orf39 gene. Genes Chromosomes Cancer 46:991-999.
28. Schoenmakers EF, Wanschura S, Mols R, Bullerdick J, Van den Berghe H, Van de Ven WJ. 1995. Recurrent rearrangements in the high mobility group protein gene, HMGI-C, in benign mesenchymal tumours. Nat Genet 10:436-444.
29. Sirvent N, Coindre JM, Maire G, Hostein I, Keslair F, Guillou L, Ranchere-Vince D, Terrier P, Pedeutour F. 2007. Detection of MDM2-CDK4 amplification by fluorescence in situ hybridization in 200 paraffin-embedded tumor samples: Utility in diagnosing adipocytic lesions and comparison with immunohistochemistry and real-time PCR. Am J Surg Pathol 31:1476-1489.
30. Yang ZQ, Imoto I, Pimkhaokham A, Shimada Y, Sasaki K, Oka M, Inazawa J. 2001. A novel amplicon at 9p23-24 in squamous cell carcinoma of the esophagus that lies proximal to GASC1 and harbors NFIB. Jpn J Cancer Res 92:423-428.
31. Zhou Z, Flesken-Nikitin A, Corney DC, Wang W, Goodrich DW, Roy-Burman P, Nikitin AY. 2006. Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer. Cancer Res 66:7889-7898.