Formulation, and evaluation of pentoxifylline-loaded poly(ε- caprolactone) microspheres

Indian Journal of Pharmaceutical Sciences

Volumn 70, Issue 3, 2008, Pages 333-337

  Tamizharasi, S ^a   Rathi, J ^a   Rathi, V ^b  

^a NANDHA COLLEGE OF PHARMACY   (India)

^b Department of Pharmacy ^*  (India)

Author keywords

Biodegradable; Microspheres; Pentoxifylline; Poly( caprolactone)

Indexed keywords

MICROSPHERE; PENTOXIFYLLINE; POLYCAPROLACTONE; SOLVENT;

ARTICLE; CONTROLLED DRUG RELEASE; DRUG DEGRADATION; DRUG DIFFUSION; DRUG FORMULATION; DRUG STABILITY; EVALUATION; EVAPORATION; IN VITRO STUDY; INFRARED SPECTROSCOPY; PARTICLE SIZE; SCANNING ELECTRON MICROSCOPY; STORAGE TEMPERATURE; TECHNIQUE;

EID: 52149104803     PISSN: 0250474X     EISSN: 19983743     Source Type: Journal    
DOI: 10.4103/0250-474X.42985     Document Type: Article

References (22)

1. Lordi NG. Sustained release dosage forms. In: Lachman L, Libermann HA, Kanig JL, editors. Theory and practice of industrial pharmacy. 3rd ed. Mumbai: Vargheese Publishing House; 1991. p. 430.
2. Torrado JJ, Illum L, Devis SS. Particle size and size distribution of albumin microspheres. Int J Pharm 1989;51:85-93.
3. Leung SS, Robinson JR. Parenteral product. In: Robinson JR, Lee VHL, editors. Controlled drug delivery, fundamentals and applications. 2nd ed. New York: Marcel Dekker Inc; 1987. p. 448-50.
4. Freeberg S, Zhu XX. Polymer microspheres for controlled drug release. Int J Pharm 2004;282:1-18.
5. Upadhye K, Bakhle S, Dixit G, Wadetwar R, Deshpande S, Nagulwar V. Preparation and evaluation of gelatin micospheres containing ciproflosacin hydrochloride. Indian Drugs 2004;41:665-9.
6. Vyas SP, Khar RK. Targeted and controlled drug delivery novel carrier systems. 1st ed. New Delhi: CBS Publishers and Distributors; 2002. p. 418.
7. Sinha VR, Bansal K, Kaushik R, Kumriq R, Trehan A. Poly-ε- caprolactone microspheres and nanospheres; an overview. Int J Pharm 2004;278:1-23.
8. Alonso MJ, Garcia ML, Espina M, Valls O, Egea MA. Aceclofenac loaded poly(ε-caprolacone) nanocapsules: Effect of coadjuvants on morphometrical properties and drug entrapment. Boll Chim Farm 2000;139:114-9.
9. Murthy RSR. Biodegradable polymers. In: Jain NK, editor. Controlled and novel drug delivery. 1st ed. New Delhi: CBS Publishers & Distributors; 1997. p. 27-51.
10. Gibaud S, Gaiq A, Astier A. Slow-release melarsoprol microparticles. Int J Pharm 2002;243:161-6.
11. Hardman JG, Limbird LE, Gilman AG, editors. Goodman and Gilman's, The pharmacological basis of therapeutics. Vol. II, 8th ed. New York: Maxwell Macmillan Publishing Corporation; 1992. p. 1699.
12. Anperiqdou A, Geogarakis M. Controlled release salbutamol sulphate microcapsules prepared by emulsion solvent evaporation technique and study on the release affected parameters. Int J Pharm 1995;115:1-8.
13. Tsankov ST, Lambov N, Minkov E. Regulation of the tetracycline hydrochloride release from polyacrylate microspheres. Pharmazie 1992;47:125-8.
14. Haznedar S, Dortunc B. Preparation and in vitro evaluation of Eudragit microspheres containing acetazolamide. Int J Pharm 2004;269:131-40.
15. Martin A, Bustamante P, Chun AHC. Physical Pharmacy. 4th ed. New Delhi: B. I. Waverty Pvt. Ltd; 1991. p. 431.
16. Dandagi PM, Mastiolimath VS, Gabad AP, Jliger SR. Mucoadhesive microspheres of propranolol hydrochloride for nasal delivery. Indian J Pharm Sci 2007;69:402-7.
17. Shabaraya AR, Narayanacharyulia R. Design and evaluation of chitosan microspheres of metoprolol tartrate for sustained release. Indian J Pharm Sci 2003;65:250-2.
18. Rajesh KS, Bhowmik BB, Sa B. Effect of polyvinylpyrrolidone on physical characteristics of ketoprofen-loaded polystryrene microparticles. Indian J Pharm Sci 2003;65:526-9.
19. 4 factorial design. Indian J Pharm Sci 2002;64:459-64.
20. Saparia B, Murthy RSR, Solanki A. Preparation and evaluation of chloroquine phosphate microspheres using cross-linked gelatin for long term drug delivery. Indian J Pharm Sci 2002;64:48-52.
21. El-Gibaly I. Development and in vitro evaluation of novel floating chitosan microcapsules for oral use: Comparison with nonfloating chitosan microspheres. Int J Pharm 2002;249:7-21.
22. Higuchi T. Mechanism of sustained - action medication: theoretical analysis of rate of release of solid drugs dispersed in solid matrices. J Pharm Sci 1963;52:1145-9.