Spinacia oleracea modulates radiation-induced biochemical changes in mice testis

Indian Journal of Pharmaceutical Sciences

Volumn 70, Issue 3, 2008, Pages 320-326

  Sisodia, Rashmi ^a   Yadav, Ritu ^a   Sharma, K ^a   Bhatia, A ^a  

^a UNIVERSITY OF RAJASTHAN   (India)

Author keywords

Antioxidant; Radioprotection; Spinacia oleracea; Testis

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; CAROTENOID; CHOLESTEROL; GLYCOGEN; MINERAL; PLANT EXTRACT; SPINACIA OLERACEA EXTRACT; UNCLASSIFIED DRUG; XANTHOPHYLL; ZEAXANTHIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPSY; CONTROLLED STUDY; DRUG DOSE COMPARISON; GAMMA RADIATION; LIPID PEROXIDATION; MALE; MOUSE; NONHUMAN; OPTIMAL DRUG DOSE; OXIDATIVE STRESS; PLANT LEAF; PROTEIN CONTENT; RADIATION EXPOSURE; RADIATION PROTECTION; SPINACH; TESTIS;

EID: 52149097400     PISSN: 0250474X     EISSN: 19983743     Source Type: Journal    
DOI: 10.4103/0250-474X.42980     Document Type: Article

References (41)

1. Bhattacharya SK, Satyam K, Ghoshal S. Antioxidant activity of glycowithanolides from Withenia somnifera. Indian J Expt Biol 1996;35:236.
2. Yen GC, Chig W, Pinder D. Extraction and identification of components from the levels of Mulberry. J Agri Food Chem 1996;44:1687-90.
3. Sano M, Ernesto C, Thomas RG, Klauber MR, Schafer K, Graundman M, et al. A controlled trial of selegiline, alpha-tocopherol or both as treatment for Alzheimer disease: The Alzheimer's disease cooperative study. N Engl J Med 1997;336:1216-22.
4. Ferreres F, Castaner M, Tomas-Barberan FA. Acylated flavonal glycosides from spinach leave (Spinacia oleracea). Phytochemistry 1997;45:701-5.
5. Gopalan C, Sastri RBV, Balasubramanian SC. Food Composition table. Nutritive value of Indian foods, National Institute of Nutrition. Hyderabad, India: Indian Council for Medical Research; 1996. p. 1-156.
6. Grossman S, Rezink R, Tamari T, Albeck M. New plant water soluble antioxidant (NAO) from spinach. In: Asada K, Toshikawa T, editors. Frontiers of reactive oxygen species in Biology and Medicine. Amsterdam, The Netherlands: Elsevier Science; 1994. p. 343-4.
7. Lomnitski L, Carbonatto M, Ben-Shaul V, Peano S, Conz A, Corradin L, et al. The prophylactic effects of natural water soluble antioxidant from spinach and apocynin in a rabbit model of lipopolysaccharide induced endotoxemia. Toxicol Pathol 2000;28:588-600.
8. Zurovsky Y, Eligal Z, Grossman S, Bergman M. Glycerol-induced augmentation of sensitivity to endotoxin rats. Toxicology 1994;32:17-26.
9. Zurovsky Y, Gispann I. Antioxidant attenuate endoto-induced acute renal failure in the rats. Am J Kidney Dis 1995;25:57.
10. Verma R, Sisodia R, Bhatia AL. Dietary Supplementation of Spinach Improves Learning and Memory in Mice after radiation Induced Oxidative Stress. Indian J Gerontol 2002;18:18-33.
11. Bickford PC, Gould TL, Chandma LK, Pollock A, Young D, Shukitt-Hale B, et al. Antioxidant-rich diets improve cerebellar physiology and motor learning in aged rats. Brain Res 2000;866:211-7.
12. Ohkawa H, Ohishi N, Yogi K. Assay for lipid peroxidation in animal tissue by thiobarbituric acid reaction. Anal Biochem 1979;95:351.
13. Bradford MM. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principal of protein-By binding. Anal Biochem 1976;72:248-54.
14. Burchard L. Micro analysis in medical biochemistry. Quoted by. King EJ and Walten IDP, London: Churchill Publishers; 1959. p. 42.
15. Montgomery R. Determination of glycogen. Arch Biochem Biophys 1957;67:378-88.
16. Sies H, Stahl W. Vitamin E and C, β-carotene and other carotenoids as antioxidants. Am J Clin Nutr 1995;62:1315S-215.
17. Sies H. Oxidative stress: Introductory remarks. London: Academic Press; 1985. p. 1-8.
18. Pryor WA, Godber SS. Noninvasive measures of oxidative stress status in humans. Free Radic Biol Med 1991;10:177-84.
19. Halliwell B. Reactive oxygen species in living system Source, biochemistry and role in human disease. Am J Med 1994;91:14-22.
20. Lomnitski L, Bergman M, Nyska A, Ben-Shaul V, Grossman S. Composition, efficacy and safety of spinach extracts. Nutr Cancer 2003;46:222-31.
21. Breitbart E, Lomnitski L, Nyska A, Malik Z, Bergman M, Sofer Y, et al. Effects of water- soluble antioxidant from spinach, NAO, on doxorubicin-induced heart injury. Hum Exp Toxicol 2001;20:337-45.
22. Van het Hoff KH, Tijberg LB, Pietrzik K, Weststrate JA. Influence of feeding different vegetables on plasma levels of carotenoids, folate and vitamin C: Effect of disruption of vegetable matrix. Br J Nutr 1999;82:203-12.
23. Guil JL, Rodriguez.Garcia I, Torija E. Nutritional and toxic factors in selected wild edible plants. Plant Foods Hum Nutr 1997;51:99-107.
24. Seifter E, Rettira G, Padwer J, Stratford F, Weinzweig J, Demetration AA, et al. Morbidity and mortality reduction by supplemental vitamin A or beta-carotene in CBA mice given total-body gamma-radiation. Natl Cancer Inst 1984;73:1167-77.
25. Mills EED. The modifying effect of β-carotene on radiation and chemotherapy induced oral mucositis. Br J Cancer 1988;57:416-7.
26. Cozzi R, Ricordy R, Aglitti T, Gatta V, Particone P, Salvia R. Ascorbic acid and β- carotene as modulators of oxidative damage. Carcinogenesis 1997;18:223-8.
27. Gerster H. Anticarcinogenic effects of common carotenoids. Int J Vit Nutr Res 1993;63:93-121.
28. Mathews-Roth MM. Recent progress in the medical application of carotenoids. Pure Appl Chem 1991;63:147-56.
29. Bergman M., Varshavsky L, Gottlieb HE, Grossman S. The antioxidant activity of aqueous spinach extract: Chemical identification of active fractions. Phytochemistry 2001;58:143-52.
30. Korkina LG, Afanasef IB, Diplock AT. Antioxidant therapy in children affected by irradiation from the Chernobyl nuclear accident. Biochem Soc Trans 1993;21:314S.
31. Kim SH, Kim JH, Djorddevic D. Effect of X-irradiation on RNA and Protein synthesis in HeLa cells. Radiat Res 1970;42:577-89.
32. Wills ED, Wilkinson AE. The effect of irradiation on lipid peroxide formation in subcellular fractions. Radiat Res 1967;31:732.
33. Grant GA. Mechanism of action of aminothiol radioprotectors. In: Radiation damage and sulfhydryl compounds. Vienna: IAEA; 1969. p. 95.
34. Zhang P, Omaye ST. ß-carotene and protein oxidation: Effect of ascorbic acid and alpha-tocopherol. Toxicology 2000;146:37-7.
35. Gupta GS, Bawa SR. Studies on glycogen and its metabolizing enzymes following radiation-induced atrophy. Radiat Res 1977;71:97-108.
36. Changamma C, Reddanna P. Effect of estradiol 17 b and PFG on glycogen metabolism of the albino rat testis. Curr Sci 1985;54:683-4.
37. Nicander L. In: The testis, Vol. 1 and 2. In: Johnson AD, Gomes WR, Van Denmark NL, editors. New York: Academic Press; 1957.
38. Maini S. Modification of Radiation Response by Sex steroids on Reporductive organs of Swiss albino mice. Ph.D. Thesis, University of Rajasthan, Jaipur (India); 1992.
39. Nair CCK, Parida DK, Nomura T. Radioprotectors in radiotherapy. J Radiat Res 2001;42:21.
40. Johnson AD. The Testis Vol 2. In: Johnson AD, Gomes WR, Van Dermark NL, editors. New York: Academic Press; 1970.
41. Verma RK, Sisodia R, Bhatia AL. Role of Spinacia oleracea as antioxidant: A biochemical study on mice brain after exposure of gamma radiation. Asian J Exp Sci 2003;17:51-7.