Functional dissection of SYG-1 and SYG-2, cell adhesion molecules required for selective synaptogenesis in C. elegans

Molecular and Cellular Neuroscience

Volumn 39, Issue 2, 2008, Pages 248-257

  Chao, Daniel L ^a   Shen, Kang ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

IgSF; Neph1; Nephrin; structure function; syg 1; syg 2; synaptic specificity; synaptogenesis

Indexed keywords

CELL ADHESION MOLECULE; NEPHRIN; PROTEIN DERIVATIVE; SYG 1 PROTEIN; SYG 2 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CAENORHABDITIS ELEGANS; CELL MIGRATION; CYTOPLASM; DEVELOPMENTAL STAGE; IN VIVO STUDY; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; SYNAPSE; SYNAPTOGENESIS;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL ADHESION; IMMUNOGLOBULINS; NERVE TISSUE PROTEINS; NEUROGENESIS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE DELETION; STRUCTURE-ACTIVITY RELATIONSHIP; SYNAPSES;

CAENORHABDITIS ELEGANS;

EID: 52049108702     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2008.07.001     Document Type: Article

References (26)

1. Bao S., and Cagan R. Preferential adhesion mediated by Hibris and Roughest regulates morphogenesis and patterning in the Drosophila eye. Developmental Cell 8 (2005) 925-935
2. Biederer T., Sara Y., Mozhayeva M., Atasoy D., Liu X., Kavalali E.T., and Sudhof T.C. SynCAM, a synaptic adhesion molecule that drives synapse assembly. Science (New York, N.Y 297 (2002) 1525-1531
3. Brummendorf T., and Rathjen F.G. Structure/function relationships of axon-associated adhesion receptors of the immunoglobulin superfamily. Current Opinion in Neurobiology 6 (1996) 584-593
4. Carthew R.W. Pattern formation in the Drosophila eye. Current Opinion in Genetics & Development 17 (2007) 309-313
5. Chen E.H., Grote E., Mohler W., and Vignery A. Cell-cell fusion. FEBS Letters 581 (2007) 2181-2193
6. Colon-Ramos D.A., Margeta M.A., and Shen K. Glia promote local synaptogenesis through UNC-6 (netrin) signaling in C. elegans. Science (New York, N.Y 318 (2007) 103-106
7. Ding M., Chao D., Wang G., and Shen K. Spatial regulation of an E3 ubiquitin ligase directs selective synapse elimination. Science (New York, N.Y. 317 (2007) 947-951
8. Donoviel D.B., Freed D.D., Vogel H., Potter D.G., Hawkins E., Barrish J.P., Mathur B.N., Turner C.A., Geske R., Montgomery C.A., Starbuck M., Brandt M., Gupta A., Ramirez-Solis R., Zambrowicz B.P., and Powell D.R. Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN. Mol. Cell. Biol. 21 (2001) 4829-4836
9. Dworak H.A., and Sink H. Myoblast fusion in Drosophila. Bioessays 24 (2002) 591-601
10. Galletta B.J., Chakravarti M., Banerjee R., and Abmayr S.M. SNS: adhesive properties, localization requirements and ectodomain dependence in S2 cells and embryonic myoblasts. Mechanisms of Development 121 (2004) 1455-1468
11. Gerke P., Huber T.B., Sellin L., Benzing T., and Walz G. Homodimerization and heterodimerization of the glomerular podocyte proteins nephrin and NEPH1. J. Am. Soc. Nephrol. 14 (2003) 918-926
12. Gerke P., Benzing T., Hohne M., Kispert A., Frotscher M., Walz G., and Kretz O. Neuronal expression and interaction with the synaptic protein CASK suggest a role for Neph1 and Neph2 in synaptogenesis. J. Comp. Neurol. 498 (2006) 466-475
13. Huber T.B., Schmidts M., Gerke P., Schermer B., Zahn A., Hartleben B., Sellin L., Walz G., and Benzing T. The carboxyl terminus of Neph family members binds to the PDZ domain protein zonula occludens-1. J. Biol. Chem. 278 (2003) 13417-13421
14. Inoue T., Oz H.S., Wiland D., Gharib S., Deshpande R., Hill R.J., Katz W.S., and Sternberg P.W. C. elegans LIN-18 is a Ryk ortholog and functions in parallel to LIN-17/Frizzled in Wnt signaling. Cell 118 (2004) 795-806
15. Kestila M., Lenkkeri U., Mannikko M., Lamerdin J., McCready P., Putaala H., Ruotsalainen V., Morita T., Nissinen M., Herva R., Kashtan C.E., Peltonen L., Holmberg C., Olsen A., and Tryggvason K. Positionally cloned gene for a novel glomerular protein-nephrin-is mutated in congenital nephrotic syndrome. Molecular Cell 1 (1998) 575-582
16. Khoshnoodi J., Sigmundsson K., Ofverstedt L.G., Skoglund U., Obrink B., Wartiovaara J., and Tryggvason K. Nephrin promotes cell-cell adhesion through homophilic interactions. Am. J. Pathol. 163 (2003) 2337-2346
17. Liu G., Kaw B., Kurfis J., Rahmanuddin S., Kanwar Y.S., and Chugh S.S. Neph1 and nephrin interaction in the slit diaphragm is an important determinant of glomerular permeability. Journal of Clinical Investigation 112 (2003) 209-221
18. Pokutta S., and Weis W.I. Structure and mechanism of cadherins and catenins in cell-cell contacts. Annual Review of Cell and Developmental biology 23 (2007) 237-261
19. Ramos R.G., Igloi G.L., Lichte B., Baumann U., Maier D., Schneider T., Brandstatter J.H., Frohlich A., and Fischbach K.F. The irregular chiasm C-roughest locus of Drosophila, which affects axonal projections and programmed cell death, encodes a novel immunoglobulin-like protein. Genes & Development 7 (1993) 2533-2547
20. Serizawa S., Miyamichi K., Takeuchi H., Yamagishi Y., Suzuki M., and Sakano H. A neuronal identity code for the odorant receptor-specific and activity-dependent axon sorting. Cell 127 (2006) 1057-1069
21. Shen K., and Bargmann C.I. The immunoglobulin superfamily protein SYG-1 determines the location of specific synapses in C. elegans. Cell 112 (2003) 619-630
22. Shen K., Fetter R.D., and Bargmann C.I. Synaptic specificity is generated by the synaptic guidepost protein SYG-2 and its receptor, SYG-1. Cell 116 (2004) 869-881
23. Srinivas B.P., Woo J., Leong W.Y., and Roy S. A conserved molecular pathway mediates myoblast fusion in insects and vertebrates. Nature Genetics 39 (2007) 781-786
24. Vishnu S., Hertenstein A., Betschinger J., Knoblich J.A., Gert de Couet H., and Fischbach K.F. The adaptor protein X11Lalpha/Dmint1 interacts with the PDZ-binding domain of the cell recognition protein Rst in Drosophila. Developmental Biology 289 (2006) 296-307
25. Yamagata M., Weiner J.A., and Sanes J.R. Sidekicks: synaptic adhesion molecules that promote lamina-specific connectivity in the retina. Cell 110 (2002) 649-660
26. Yoshikawa S., McKinnon R.D., Kokel M., and Thomas J.B. Wnt-mediated axon guidance via the Drosophila Derailed receptor. Nature 422 (2003) 583-588