Radioprotective potential of Trigonella foenum graecum seeds extract

Pharmacologyonline

Volumn 2, Issue , 2008, Pages 14-26

  Chaudhary, Ranu ^a   Jahan, Swafiya ^a   Gupta, Uma ^a   Goyal, P K ^a  

^a UNIVERSITY OF RAJASTHAN   (India)

Author keywords

Glutathione; Irradiation; Lipid peroxidation; Radioprotection; Spleen colony assay; Trigonella foenum

Indexed keywords

GLUTATHIONE; LIPID PEROXIDE; RADIOPROTECTIVE AGENT; TRIGONELLA FOENUM GRAECUM EXTRACT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLONY FORMING UNIT S; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG MECHANISM; DRUG MEGADOSE; ENZYME ACTIVITY; GAMMA RADIATION; LIPID PEROXIDATION; MALE; MOUSE; NONHUMAN; OPTIMAL DRUG DOSE; PLANT SEED; RADIATION EXPOSURE; RADIATION PROTECTION; SPLEEN; SURVIVAL RATE; TREATMENT DURATION; WHOLE BODY RADIATION;

EID: 52049097318     PISSN: None     EISSN: 18278620     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. 0 human lymphocytes. Environ. Mol. Mut, 37: 117-127.
2. Weiss, J.F. and Landauer, M.R. 2003. Protection against ionizing radiation by antioxidant nutrients and phytochemicals. Toxicology 189: 1-20.
3. Mettler, F.A.J. and Voelz, G.L. 2002. Major radiation exposure - what to expect and how to respond. N. Engl. J. Med. 346: 1554-1561.
4. Hensley, M.L., Schuchter, L.M., Lindley, C., Meropol, N.J., Cohen, G.I., Broder, G. 1999. American society of clinical oncology clinical practice guidelines for the use of chemotherapy and radiotherapy protectants. J. Clin. Oncol. 17: 3333-3335.
5. Landauer, M.R., Srinivasan, V., Seed, T.M. 2003. Genistein treatment protects mice from ionizing radiation injury. J. Appl. Toxicol. 23: 379-385.
6. Sweeny, T.R (1979). Survey of compounds from the antiradiation drug development program of the U.S. Army Medical Research and Development Command. Government printing office, Washington D.C. publication, pp. 308-318.
7. Maisin, J.R, Bacq and Alexander Award lecture. 1998. Chemical radioprotection: past, present and future prospects. Int. J. Radiat. Biol, 73, 443-450.
8. Kitts, D.D., Wijewickrem, A.N., Hu, C. (2000). Antioxidant properties of a North American Ginseng Extract. Mol. Cell. Biochem. 203: 1-10.
9. Kitts, D.D., Wijewickrem, A.N., Hu, C. 2000. Efficacy and safety of Ginseng. Pub. Health. Nut. 4: 473-485.
10. Abdel-Berry, J.A., Abdel-Hassan, I.A., Al-Hakeim, M.H. 1997. Hypoglycemic and antihyperglycemic effects of Trigonella foenumgraecum leaf in normal and alloxan induced diabetic rats. J. Ethnopharmacol. 58: 149-155.
11. Zia, T., Hasnain, S.N., Hasan S.K. 2001. Evaluation of the oral hypoglycemic effect of Trigonella foenum-graecum L (methi) in normal mice. J. Ethnopharmacol. 75: 191-195.
12. Vats, V., Grover, J.K., Rathi, S.S. 2002. Evaluation of antihyperglycemic effect of Trigonella foenum-graecum Linn, Ocimum sanctum Linn and Pterocarpus marsupium Linn in normal and alloxanized diabetic rats. J. Ethnopharmacol. 79: 95-100.
13. Basch, E., Ulbricht, C., Kuo, G., Szapary, P., Smith, M. 2003. Therapeutic applications of fenugreek. Altern. Med. Rev, 8: 20-27.
14. Sharma, R.D., Sarkar, A., Hazara, D.K., et al. 1996. Hypolipidaemic effect of Fenugreek seeds: A chronic study in non-insulin dependant diabetic patients, Phytotherapy Res. 10: 330-334.
15. Thakur, A.M., Sarvaiya, J,G., Bhavasar, S.K., et al. 1994. Studies on anti-inflammatory activities of Trigonella in rats. In update Ayurveda, 75, Bombay, India.
16. Puri, D. 1998. Therapuetic potential of Fenugreek, Indian J of Physiology & Pharmacology, 42, 423-424.
17. Suja, P.R., Anuradha, C.V. and Vishwanathan, P. 2002. Gastroprotective effect of Fenugreek seeds (Trigonella foenum greacum) on experimental gastric ulcer in rats, Journal of Ethnopharmacology. 81, 393-397.
18. Sur, P., Das, M., Gomes, A. et al. 2001. Trigonella foenum greacum (Fenugreek) seed extract as an antineoplastic agent. Phytotherapy Res. 15, 257-259.
19. Till JE and Me Culloch EA. 1963. Early repair processes in marrow cells irradiated and proliferating in vivo. Rad. Res., 18, 96-105.
20. Ohkhwa H, Ohishi N, Yogi, K. 1979. Assay for lipid peroxidation in animal tissue by thiobarbituric acid reaction. Analyt. Biochem, 95, 351-357.
21. Moron MS, Depierre JW, Mannervick B. 1979. Levels of glutathione, glutathione reductase and glutathione-s-transeferase activities in rat lung and liver. Biochem. Biophys. Acta, 582, 67-78.
22. Beutler E, Duron O, Kelly BM. 1963. Improved method for the determination blood glutathione. J Lab Clin Med, 61, 582-888.
23. Baliga, M.S., Jagetia, G.C., Venkatesh, P., Reddy, R. & Ulloor, J.N 2004. Radioprotective effect of abana, a polyherbal drug following total body irradiation. British J. of Radiology, 77, 1027-1035.
24. Griffiths, N.M, Dublineau, I, Francois, A. and Ksas, B. 1999. Radiation-induced colonic injury: Decreased fluid absorption and effects of granisetron a 5-HT3 receptor inhibitor. Adv. Radiar. Biol. Peace 2: 1-10.
25. Nakamura, W., Kojima, E., Minamizawa, H., Kankura, T., Kabayashi, S. and Eto, H. 1968. In: Comparative Cellular and Species Radio sensitivity in Animals, Eds. Bond. V.P. and Sugahara, T. Igaku Shoin, Tokyo.
26. Nunia, V. and Goyal, P.K. 2004. Prevention of gamma radiation induced anemia in mice by Dilitiazem. J. Radiat. Res., 45, 11-17.
27. Samarth, R.M. and Kumar A. 2003. Radioprotection of Swiss albino mice by plant extract Mentha Piperita (Lima.). J. Radiar. Res, 44, 101-109.
28. Singh I., Sharma S., Jindal A., Soyal, D. and Goyal, P.K. 2006. Protective effect of Emblica officinalis fruit extract against gamma irradiation in mice. Pharmacology online 2: 128-150.
29. Sancheti G. and Goyal, P.K. 2007. Prevention of radiation-induced hematological alterations by medicinal plant Rosemarinus officinalis in mice. Afr. J. Alt. Comp. Med. 4, 165-172.
30. Jindal, A., Soyal, D. and Singh, I. 2006. Modification of radiation-induced damage in mice by Rosemarinus officinalis extract (ROE). J. of Annals, 13, 65-71.
31. Arti, A., Byren, T.M., Nair, M.G. et al., 2000. Modulation of lipo-somal membrane fluidity by flavanoids and isoflavanoids. Archives of Biochemistry & Biophysics, 373, 102-109
32. Anuradha, C.V., and Ravikumar, P. 1998. Anti lipid peroxidative activity of seeds of Fenugreek (Trigonella foenum graecum). Medical Science Research, 26, 317-321
33. Anuradha, C.V. and Ravikumar, P. 2001. Restoration of tissue anti-oxidants by Fenugreek (Trigonella foenum graecum) seeds in alloxan-diabetic rates. Indian J of Physiology & Pharmacology, 45, 408-420.
34. Puthenpura, T., Nambisan, B. and Sudhakaran, P. 2006. Hypolipidaemic effect of chemically different mucilages in rats: a comparative study. British J. of Nutrition, 96, 1021-1029.
35. Simon, J.E., Chadwick, A.F. and Craker, L.E. 1984. Herbs: Aja indexed Bibliography. 1971-1980.
36. Hall, E.J. 1978. In: Radiobiology for the Radiologists, 2nd edition, Harper and Row Publishers, Philadelphia.
37. Singh RP, Banerjee S, Kumar PV, Raveesha KA, Rao AR. 2006. Tinospora cordifolia induces enzymes of carcinogen/drug metabolism and antioxidant system, and inhibits lipid peroxidation in mice. Phytomedicine. 13(1-2): 74-84.
38. Subramanian, K., Ramamurthy, N., Gunasekaran, P., Varalakshmi, E and Anuradha, C. 2006. Fenugreek (Trigonella foenum graecum) seed extract prevents ethanol-induced toxicity and apoptosis in Chang liver cells. Alcohol & Alcoholism. Vol. 41, No. 3, pp 267-273.