Hydrophobic interaction chromatography of soluble interleukin I receptor type II to reveal chemical degradations resulting in loss of potency

Analytical Chemistry

Volumn 80, Issue 18, 2008, Pages 7022-7028

  Zhang, Yuling ^a   Martinez, Theresa ^a   Woodruff, Brian ^a   Goetze, Andy ^a   Bailey, Robert ^a   Pettit, Dean ^a   Balland, Alain ^a  

^a AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDS; AGGLOMERATION; AMINATION; AMINES; AMINO ACIDS; CHEMOTHERAPY; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; DEGRADATION; DRUG DELIVERY; DRUG DOSAGE; DRUG INTERACTIONS; ELECTRON TRANSITIONS; FLOW INTERACTIONS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHOBICITY; ISOMERIZATION; ISOMERS; MASS SPECTROMETRY; ORGANIC ACIDS; PORT TERMINALS; SULFATE MINERALS;

ACCELERATED DEGRADATION; ANALYTICAL TECHNIQUES; ASPARTATE; CHEMICAL-; CONFORMATIONAL CHANGES; CYANOGEN BROMIDES; DEAMIDATION; DRUG SUBSTANCES; HYDROPHOBIC INTERACTION CHROMATOGRAPHY; MOLECULAR MODELLING; N-TERMINAL SEQUENCING; RETENTION TIME; REVERSED-PHASE CHROMATOGRAPHY; TYPE II;

HYDROPHOBIC CHROMATOGRAPHY;

ASPARAGINE; CYANOGEN BROMIDE; INTERLEUKIN 1 RECEPTOR TYPE II;

ANALYTIC METHOD; ANIMAL CELL; ARTICLE; CHROMATOGRAPHY; DEAMINATION; DEGRADATION; DRUG STABILITY; ISOMERIZATION; MASS SPECTROMETRY; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; REVERSED PHASE LIQUID CHROMATOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; CATTLE; CHROMATOGRAPHY; CYANOGEN BROMIDE; HUMANS; HYDROPHOBICITY; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, INTERLEUKIN-1 TYPE I; RECOMBINANT PROTEINS; SOLUBILITY; TEMPERATURE;

EID: 51949099133     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac800928z     Document Type: Article

References (30)

1. Shukla, A. A.; Peterson, J.; Sorge, L.; Lewis, P.; Thomas, S.; Waugh, S. Biotechnol. Prog. 2002, 18, 556-64.
2. Kwong, M.; Harris, R. Protein Sci. 1994, 3, 147-149.
3. Valliere-Douglass, J.; Jones, L.; Shpektor, D.; Kodama, P.; Wallace, A.; Balland, A.; Bailey, R.; Zhang, Y. Anal. Chem. 2008, 80, 3168-3174.
4. McFadden, P. N.; Clarke, S. J. Biol. Chem. 1986, 261, 11503-11.
5. Stephenson, R.; Clarke, S. J. Biol. Chem. 1989, 264, 6164-6170.
6. Huang, L.; Lu, J.; Wroblewski, V.; Beals, J.; Riggin, R. Anal. Chem. 2005, 77, 1432-1439.
7. Zhang, W.; Czupryn, M. J. Pharm. Biomed. Anal. 2003, 30, 1479-1490.
8. Lyubarskaya, Y.; Houde, D.; Woodard, J.; Murphy, D.; Mhatre, R. Anal. Biochem. 2006, 348, 24-39.
9. Orpiszewski, J.; Schormann, N.; Kluve-Beckerman, B.; Liepnteks, J.; Benson, M. FASEB J. 2000, 14, 1255-1263.
10. Napper, S.; Delbaere, T.; Waygood, E. J. Biol. Chem. 1999, 274, 21776-21782.
11. Cacia, J.; Quan, C.; Vasser, M.; Sliwkowski, M.; Frenz, J. J. Chromatogr., A 1993, 634, 229-239.
12. Teshima, G.; Porter, J.; Yim, K.; Ling, V.; Guzzetta, A. Biochemistry 1991, 30, 3916-3922.
13. Violand, B.; Schlittler, M.; Kolodiej, E.; Toren, P.; Cabonce, M.; Siegel, M.; Duffin, K.; Zobel, J.; Smith, C.; Tou, J. Protein Sci. 1992, 1, 1634-1641.
14. Bischoff, R.; Lepage, P.; Jaquinod, M.; Cauet, G.; Acker-Klein, M.; Clesse, D.; Laporte, M.; Bayol, A.; Van Dorsselaer, A.; Roitsch, C. Biochemistry 1993, 32, 725-734.
15. Teshima, G.; Stults, J.; Ling, V.; Canova-Davis, E. J. Biol. Chem. 1991, 266, 13544-13547.
16. Chu, G.; Chelius, D.; Gang, X.; Khor, H.; Coulibaly, S.; Bondarenko, P. Pharm. Res. 2007, 24, 1145-1156.
17. Athmer, L.; Kindrachuk, J.; Georges, F.; Napper, S. J. Biol. Chem. 2002, 277, 30502-30507.
18. Hsu, Y.; Chang, W.; Mendiaz, E.; Hara, S.; Chow, D.; Mann, M.; Langley, K.; Lu, H. Biochemistry 1998, 37, 2251-2262.
19. Colotta, F.; Bertini, M.; Polentarutti, N.; Sironi, M.; Giri, J.; Dower, S.; Sims, J.; Mantovani, A Science 1993, 261, 472-475.
20. Sims, J.; Smith, D. Eur. Cytokine Network 2003, 14, 77-81.
21. O'Connor, J.; Satpathy, A.; Hartman, M.; Horvath, E.; Kelley, K.; Dantzer, R.; Johnson, R.; Freund, G. J. Immunol. 2005, 174, 4991-4997.
22. Garlind, A.; Brauner, A.; Hojeberg, B.; Basun, H.; Schultzberg, M. Brain Res. 1999, 826, 112-116.
23. Smith, D.; Ketchem, R.; Moore, H.; Anderson, Z.; Renshaw, B.; Friend, D.; Sims, J. J. Biol. Chem. 2002, 277, 47619-47625.
24. Sims, J. Curr. Opin. Immunol. 2002, 14, 117-122.
25. Morris, A. E.; Lee, C. C.; Hodges, K.; Aldrich, T. L.; Krantz, C.; Smidt, P. S.; Thomas, J. N. Animal Cell Technology; Kluwer Academic Publishers: Norwell, MA, 1997; pp 529-534.
26. Smith, D.; Hanna, R.; Friend, D.; Moore, H.; Chen, H.; Farese, A. M.; MacVittie, T. J.; Virca, G. D.; Sims, J. Immunity 2003, 18, 87-96.
27. Janson, J.; Ryden, L. Protein purification-Principles, High Resolution, Methods, and Applications; John Wiley & Sons Inc.: Somerset, NJ, 1997; pp 287-290.
28. Kaiser, R.; Metzka, L. Anal. Biochem. 1999, 266, 1-8.
29. Vigers, G.; Anderson, L.; Caffes, P.; Brandhuber, B. Nature 1997, 386, 190-194.
30. Schreuder, H.; Tardif, C.; Trump-Kallmeyer, S.; Soffientini, A.; Sarubbi, E.; Akeson, A.; Bowlin, T.; Yanofsky, S.; Barrett, R. Nature 1997, 386, 194-200.