Localization of sex steroid receptors in human skin

Histology and Histopathology

Volumn 19, Issue 2, 2004, Pages 629-636

  Pelletier, Georges ^a   Ren, L ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

Hair follicles; Human skin; Sebaceous glands; Sex steroid receptors epidermis

Indexed keywords

ANDROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; PROGESTERONE RECEPTOR; SEX HORMONE; STEROID RECEPTOR;

BASAL CELL; CELL NUCLEUS; CELLULAR DISTRIBUTION; DERMIS; EPIDERMIS; FIBROBLAST; HAIR FOLLICLE; HUMAN; KERATINOCYTE; NONHUMAN; PROTEIN EXPRESSION; REVIEW; SEBACEOUS GLAND; SECRETORY CELL; SKIN APPENDAGE; SKIN RECEPTOR; SWEAT GLAND;

EPIDERMIS; ESTROGEN RECEPTOR BETA; FEMALE; GONADAL STEROID HORMONES; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; RECEPTORS, ANDROGEN; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; RECEPTORS, STEROID; SEBACEOUS GLANDS; SEX FACTORS; SKIN;

EID: 1842611082     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (38)

1. Ashcroft G.S., Greewell-Wild T., Horan M.A., Wahl S.M. and Ferguson M.W. (1999). Topical estrogen accelerates cutaneous wound healing in aged humans associated with an altered inflammatory response. Am. J. Pathol. 155, 1137-1146.
2. Bird J., Li X. and Lei Z.M. (1998). Luteinizing hormone and human chorionic gonadotropin decrease type 2 5 alpha-reductase and androgen receptor protein levels in women's skin. J Clin. Endocrinol. Metab. 85, 1176-1182.
3. Blauer M., Vaalasti A., Pauli S.L., Ylikomi T., Joensuu T. and Tuohimaa P. (1991) Localization of the androgen receptor in human skin. J. Invest. Dermatol. 97, 264-268.
4. Boudou P., Soliman H., Chivot M., Villette J.M., Vexiau P., Belanger A. and Fiet J. (1995). Effect of oral isotretinoin treatment on skin androgen receptor levels in male acneic patients. J. Clin. Endocrinol. Metab. 80, 1158-1161.
5. Chang C.S., Kokontis J. and Liao S.T. (1988). Molecular cloning of human and rat complementary DNA encoding androgen receptors. Science 240, 324-326.
6. Chen W.C., Thiboutot D. and Zouboulis C.C. (2002). Cutaneous androgen metabolism: Basic research and clinical perspectives. J. Invest. Dermatol. 119, 992-1007.
7. Choudhry R., Hodgins M.B., Van der Kwast T.K., Brinkkmann A.O. and Boersma W.J.A. (1992). Localization of androgen receptors in human skin by immunohistochemistry: Implications for the hormonal regulation of hair growth, sebaceous glands and sweet glands. J. Endocrinol. 133, 467-475.
8. Cooke P.S., Young P. and Cunha G.R. (1991). Androgen receptor expression in developing male reproductive organs. Endocrinology 128, 2867-2873.
9. Cotsarelis G. (2000). Hair follicle stem cells: Their location and roles. In: Hair ant its disorders, biology, pathology and management. Camacho F.M., Randall V.A. and V.H. P. (eds). Martin Dunitz. Londo. npp. 39-47.
10. Cunliffe W.J., Shuster S. and Smith A.J. (1969). The effect of topical cyproterone acetate on sebum secretion in patients with acne. Br. J. Dermatol. 81, 200-201.
11. Ebling F.J. (1990). The hormonal control of hair growth. In: Hair and hair diseases. Happle C.E.O.R. (ed). Springer-Verlag. pp. 267-299.
12. Esmaeli B., Harvey J.T. and Hewlett B. (2000). Immunohistochemical evidence for estrogen receptors in meibomian glands. Ophtalmology 107, 180-184.
13. Graham J.D. and Clarke C.L. (1997). Physiological action of progesterone in target tissues. Endocr. Rev. 18, 502-519.
14. Green S., Walter P., Kumar V., Krust V., Bornert J.M., Argos P. and Chambon P. (1986). Human oestrogen receptor cDNA: Sequence, expression and homology to v-erb-A. Nature 320, 134-139.
15. Guy R., Ridden C. and Kealy T. (1996). The improved organ maintenance of the human sebaceous gland: Modeling in vitro the effects of epidermal growth factor, androgens, estrogens, 13-cis retinoic acid, and pehnol red. J. Invest. Dermatol. 106, 454-460.
16. Hodgins M.B., Spike R.C., Mackie R.M. and MacLean A.B. (1998). An immunohistochemical study of androgen, estrogen and progesterone receptors in the vulva and vagina. Br. J. Obstet. Gynecol. 105, 216-222.
17. Horne K.A., Joboda C.A.B. and Oliver R.F. (1986). Whisker growth induced by implantation of cultured Vihissa dermal papilla cells in the adult rat. J. Embryol. Exp. Morphol. 97, 111-124.
18. Kastner P., Krust A., Turcotte B., Stropp V., Tora L., Gronemeyer H. and Chambon P. (1990). Two distinct estrogen-regulated promoters generate transcripts encoding the two functionnally different human progesterone receptor forms A and B. EMBO J. 9, 1603-1614.
19. Kimura N., Mizokami A., Oonuma T., Sasano H. and Nagura H. (1993). Immunocytochemical localization of androgen receptor with polyclonal antibody in paraffin-embedded human tissues. J. Histochem. Cytochem. 41, 671-678
20. Kohlberger P.D., Joura E.A. and Bancher D. (1998). Evidence of androgen receptor expression in lichen sclerosus: An immunohistochemical study. J. Soc. Gynecol. Investig. 6, 331-333.
21. Kuiper G.G.J.M., Carlsson B., Grandien K., Enmark E., Haggblad J., Nilsson S. and Gustafsson J.A. (1997). Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β. Endocrinology 138, 863-870.
22. Labrie F., Luu-The V., Labrie C., Pelletier G. and El-Alfy M. (2000). Intracrinology and the skin. Horm. Res. 54, 218-229.
23. Lasnitzki I. and Mizuno T. (1980). Prostatic induction: interaction of epithelium and mesenchyme from normal wild-type mice and androgen insensitive mice with testicular feminization. J. Endocrinol. 85, 423-428.
24. Liang T., Hoyer S., Yu R., Soltani K., Lorincz A.L., Hiipakka R.A. and Liao S. (1993). Immunohistochemical localization of androgen receptors in human skin using monoclonal antibodies against the androgen receptor. J. Invest. Dermatol. 100, 663-666.
25. Lubahn D.B., Joseph D.R., Sullivan P.M., Willard H.F., French F.S. and Wilson E.M. (1988). Cloning of human androgen receptor complementary DNA and localization to the X chromosome. Science 240, 327-330.
26. Maclean A.R., Nicol L.A. and Hodgens M.D. (1990). Immunohistochemical localization of estrogen receptors in the vulva and vagina. J. Reprod. Med. 1015-1016.
27. Mosselman S., Polman J. and Dijkema R. (1996). ERb: identification and characterization of a novel human estrogen receptor. FEBS Lett. 392, 49-53.
28. Oh H.S. and Smart R.C. (1996). An estrogen receptor pathway regulates the telogen-a-nagin hair follicle transition and influences epidermal cell proliferation. Proc. Natl. Acad. Sci. USA 93, 12525-12530.
29. Pelletier G. (2000). Localization of androgen and estrogen receptors in rat and primate tissues. Histol. Histopathol. 15, 1261-1270.
30. Pelletier G., Labrie C. and Labrie F. (2000). Localization of oestrogen receptor α, oestrogen receptor β and androgen receptors in the rat reproductive organs. J. Endocrinol. 165, 359-370.
31. Pochi P.E. and Strauss J.S. (1974). Endocrinologic control of the development of activity of the human sebaceous gland. J. Invest. Dermatol. 62, 191-201.
32. Rees J. and Shuster S. (1981). Pubertal induction of sweat gland cell activity. Clin. Sci., 60, 689-692.
33. Schmidt J. R., Lindmaier A. and Spona J. (1990). Hormone receptors in public skin of premenopausal and postmenopausal females. Gynecol. Obstet. Invest. 30, 97-100.
34. Sweeney T.M., Szarnicki R.J., Strauss J.S. and Pachi P.E. (1969). The effects of estrogen and androgen on the sebaceous gland turnover time. J. Invest. Dermatol. 53, 8-10.
35. Thornton M.J., Taylor A.H. and Mulligan K. (2003). Oestrogen receptor beta is the predominant estrogen receptor in human scalp skin. Exp. Dermatol. 12, 181-190.
36. Viae J., Su H., Reano A., Kanitakis J., Chardonnet X. and Thivalet J. (1989). Distribution of an estrogen receptor-related protein (P29) in normal skin and in cultured human keratinocytes. J. Dermatol. 16, 98-102.
37. Wallace M.L. and Smaller B.R. (1998). Estrogen and progesterone receptors in androgenic alopecia versus alopecia areata. Am. J. Dermatol. 2, 160-163.
38. West N.B., Carlisle K.S. and Brenner R.M. (1990). Progesterone treatment suppresses estrogen receptor in the sex skin of Macaca Nemestrina. J. Ster. Biochem. 35, 481-485.