A general and efficient route to 6-methyl-pyrazin-2-yl-amines: Alkylation of 2,6-dichloropyrazine via malonate derivatives

Journal of Heterocyclic Chemistry

Volumn 45, Issue 5, 2008, Pages 1451-1456

  Colbon, Paul J J ^a   Foster, Alison C ^a   Giles, Melvyn E ^a   Patel, Zakariya ^a   Singleton, John T ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

(6 CHLOROPYRAZIN 2 YL)ACETIC ACID; 2,6 DICHLOROPYRAZINE; ACETIC ACID DERIVATIVE; MALONIC ACID DERIVATIVE; PYRAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; AMINATION; ARTICLE; ARYLATION; DECARBOXYLATION; HYDROLYSIS; SYNTHESIS;

EID: 51849099452     PISSN: 0022152X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jhet.5570450531     Document Type: Article

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