Rapid induction of OX40 ligand on primary T cells activated under DNA-damaging conditions

Human Immunology

Volumn 69, Issue 9, 2008, Pages 533-542

  Kondo, Kayo ^a   Okuma, Kazu ^a   Tanaka, Reiko ^a   Matsuzaki, Goro ^a   Ansari, Aftab A ^b   Tanaka, Yuetsu ^a  

^a UNIVERSITY OF THE RYUKYUS   (Japan)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Activated T cells; Costimulation; DNA stress; Human OX40L; Senescence

Indexed keywords

CD3 ANTIBODY; CYCLOHEXIMIDE; DACTINOMYCIN; DNA; FLUOROURACIL; MITOMYCIN C; OX40 LIGAND; RNA;

ANIMAL CELL; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL PROLIFERATION; DNA DAMAGE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; X IRRADIATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD3; ANTIGENS, CD70; B-LYMPHOCYTES; CD30 LIGAND; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; DNA DAMAGE; HUMANS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MITOMYCIN; NUCLEIC ACID SYNTHESIS INHIBITORS; OX40 LIGAND; PROTEIN SYNTHESIS INHIBITORS; ULTRAVIOLET RAYS;

EID: 51749119931     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2008.07.001     Document Type: Article

References (44)

1. Tanaka Y., Inoi T., Tozawa H., Yamamoto N., and Hinuma Y. A glycoprotein antigen detected with new monoclonal antibodies on the surface of human lymphocytes infected with human T-cell leukemia virus type-I (HTLV-I). Int J Cancer 36 (1985) 549-555
2. Miura S., Ohtani K., Numata N., Niki M., Ohbo K., Ina Y., et al. Molecular cloning and characterization of a novel glycoprotein, gp34, that is specifically induced by the human T-cell leukemia virus type I transactivator p40tax. Mol Cell Biol 11 (1991) 1313-1325
3. Godfrey W.R., Fangoni F.F., Harara M.A., Buck D., and Engelman E.G. Identification of a human OX-40 ligand, a costimulator of CD4+ T cells with homology to tumor necrosis factor. J Exp Med 180 (1994) 757-762
4. Paterson D.J., Jefferies W.A., Green J.R., Brandon M.R., Corthesy P., Puklavec M., et al. Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts. Mol Immunol 24 (1987) 1281-1290
5. Croft M. Costimulation of T cells by OX40, 4-1BB, and CD27. Cytokine Growth Factor Rev 14 (2003) 265-273
6. Sugamura K., Ishii N., and Weinberg A.D. Therapeutic targeting of the effector T-cell co-stimulatory molecule OX40. Nat Rev Immunol 4 (2004) 420-431
7. Watts T.H. TNF/TNFR family members in costimulation of T cell responses. Annu Rev Immunol 23 (2005) 23-68
8. Song J., So T., Cheng M., Tang X., and Croft M. Sustained survivin expression from OX40 costimulatory signals drives T cell clonal expansion. Immunity 22 (2005) 621-631
9. Compaan D.M., and Hymowitz S.G. The crystal structure of the costimulatory OX40-OX40L complex. Structure 14 (2006) 1321-1330
10. Stuber E., Neurath M., Calderhead D., Fell H.P., and Strober W. Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells. Immunity 2 (1995) 507-521
11. Ohshima Y., Tanaka Y., Tozawa H., Takahashi Y., Maliszewski C., and Deledpesse G. Expression and function of OX40 ligand on human dendritic cells. J Immunol 159 (1997) 3838-3848
12. Imura A., Hori T., Imada K., Kawamata S., Tanaka Y., Imamura S., et al. OX40 expressed on fresh leukemic cells from adult T-cell leukemia patients mediates cell adhesion to vascular endothelial cells: implication for the possible involvement of OX40 in leukemic cell infiltration. Blood 89 (1997) 2951-2958
13. Ito T., Wang Y.H., Duramad O., Hori T., Delespesse G.J., Watanabe N., et al. TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand. J Exp Med 202 (2005) 1213-1223
14. Soroosh P., Ine S., Sugamura K., and Ishii N. OX40-OX40 ligand interaction through T cell-T cell contact contributes to CD4 T cell longevity. J Immunol 176 (2006) 5975-5987
15. Zingoni A., Sornasse T., Cocks B.G., Tanaka Y., Santoni A., and Lanier L.L. Cross-talk between activated human NK cells and CD4+ T cells via OX40-OX40 ligand interactions. J Immunol 173 (2004) 3716-3724
16. Kashiwakura J., Yokoi H., Saito H., and Okayama Y. T cell proliferation by direct cross-talk between OX40 ligand on human mast cells and OX40 on human T cells: comparison of gene expression profiles between human tonsillar and lung-cultured mast cells. J Immunol 173 (2004) 5247-5257
17. Takahashi Y., Tanaka R., Yamamoto N., and Tanaka Y. Enhancement of OX40-induced apoptosis by TNF coactivation in OX40-expressing T cell lines in vitro leading to decreased targets for HIV type 1 production. AIDS Res Hum Retroviruses 24 (2008) 423-435
18. Kondo K., Okuma K., Tanaka R., Zhang L.F., Kodama A., Takahashi Y., et al. Requirements for the functional expression of OX40 ligand on human activated CD4+ and CD8+ T cells. Hum Immunol 68 (2007) 563-571
19. Tozawa H., Andoh S., Takayama Y., Tanaka Y., Lee B., Nakamura H., et al. Species-dependent antigenicity of the 34-kDa glycoprotein found on the membrane of various primate lymphocytes transformed by human T-cell leukemia virus type-I (HTLV-I) and simian T-cell leukemia virus (STLV-I). Int J Cancer 41 (1988) 231-238
20. Takahashi Y., Tanaka Y., Yamashita A., Koyanagi Y., Nakamura M., and Yamamoto N. OX40 stimulation by gp34/OX40 ligand enhances productive human immunodeficiency virus type 1 infection. J Virol 75 (2001) 6748-6757
21. Baba E., Takahashi Y., Lichtenfeld J., Tanaka R., Yoshida A., Sugamura K., et al. Functional CD4 T cells after intercellular molecular transfer of 0X40 ligand. J Immunol 167 (2001) 875-883
22. Traggiai E., Chicha L., Mazzucchelli L., Bronz L., Piffaretti J.C., Lanzavecchia A., et al. Development of a human adaptive immune system in cord blood cell-transplanted mice. Science 304 (2004) 104-107
23. Rizza P., Santini S.M., Logozzi M.A., Lapenta C., Sestili P., Gheradi G., et al. T-cell dysfunctions in hu-PBL-SCID mice infected with human immunodeficiency virus (HIV) shortly after reconstitution: in vivo effects of HIV on highly activated human immune cells. J Virol 70 (1996) 7958-7964
24. Rogers P.R., Dong J., Gramalia I., Killeen N., and Croft M. OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells. Immunity 15 (2001) 445-455
25. Yoshida H., Kawane K., Koike M., Mori Y., Ushiyama Y., and Nagata S. Phosphatidylserine-dependent englfment by macrophages of nuclei from erythroid precursor cells. Nature 437 (2005) 754-758
26. Zhang L.F., Okuma K., Tanaka R., Kodama A., Kondo K., Ansari A.A., et al. Generation of mature dendritic cells with unique phenotype and function by in vitro short-term culture of human monocytes in the presence of interleukin-4 and interferon-beta. Exp Biol Med 233 (2008) 721-731
27. Johansson U., Walther J.L., Smed S.A., and Spetz A.L. Triggering of dendritic cell responses after exposure to activated, but not resting, apoptotic PBMCs. J Immunol 179 (2007) 1711-1720
28. Morris N.P., Peters C., Montler R., Hu H.M., Curti B.D., Urba W.J., et al. Development and characterization of recombinant human Fc:OX40L fusion protein linked via a coiled-coil trimerization domain. Mol Immunol 44 (2007) 3112-3121
29. Muller N., Wyzgol A., Munkel S., Pfizenmaier K., and Wajant H. Activity of soluble OX40 ligand is enhanced by oligomerization and cell surface immobilization. FEBS J 275 (2008) 2296-2304
30. Ruby C.E., Redmond W.L., Haley D., and Weinberg A.D. Anti-OX40 stimulation in vivo enhances CD8+ memory T cell survival and significantly increases recall responses. Eur J Immunol 37 (2007) 157-166
31. Ndhlovu L.C., Takeda I., Sugamura K., and Ishii N. Expanding role of T-cell costimulators in regulatory T-cell function: recent advances in accessory molecules expressed on both regulatory and nonregulatory T cells. Crit Rev Immunol 24 (2004) 251-266
32. Redmond W.L., and Weinberg A.D. Targeting OX40 and OX40L for the treatment of autoimmunity and cancer. Crit Rev Immunol 27 (2007) 415-436
33. Salek-Ardakani S., and Croft M. Regulation of CD4 T cell memory by OX40 (CD134). Vaccine 24 (2006) 872-883
34. Song A., Tang X., Harms K.M., and Croft M. OX40 and Bcl-xL promote the persistence of CD8 T cells to recall tumor-associated antigen. J Immunol 175 (2005) 3534-3541
35. Piconese S., Valzasina B., and Colombo M.P. OX40 triggering blocks suppression by regulatory T cells and facilitates tumor rejection. J Exp Med 205 (2008) 825-839
36. Colombo M.P., and Piconese S. Regulatory-T-cell inhibition versus depletion: the right choice in cancer immunotherapy. Nat Rev Cancer 7 (2007) 880-887
37. Tanaka H., Demeure C.E., Rubio M., Delespesse G., and Sarfati M. Human monocyte-derived dendritic cells induce naive T cell differentiation into T helper cell type 2 (Th2) or Th1/Th2 effectors. Role of stimulator/responder ratio. J Exp Med 192 (2000) 405-412
38. Morimoto S., Kanno Y., Tanaka Y., Hashimoto H., Jacquot S., Morimoto C., et al. CD134L engagement enhances human B cell Ig production: CD154/CD40, CD70/CD27, and CD134/CD134L interactions coordinately regulate T cell-dependent B cell responses. J Immunol 164 (2000) 4097-4104
39. Fujita T., Kambe N., Uchiyama T., and Hori T. Type I interferons attenuate T cell activating functions of human mast cells by decreasing TNF-alpha production and OX40 ligand expression while increasing IL-10 production. J Clin Immunol 26 (2006) 512-518
40. Murata S., Ladle B.H., Kim P.S., Lutz E.R., Wolpoe M.E., Ivie S.E., et al. OX40 costimulation synergizes with GM-CSF whole-cell vaccination to overcome established CD8+ T cell tolerance to an endogenous tumor antigen. J Immunol 176 (2006) 974-983
41. Higashimura N., Takasawa N., Tanaka Y., Nakamura M., and Sugamura K. Induction of OX40, a receptor of gp34, on T cells by trans-acting transcriptional activator, Tax, of human T-cell leukemia virus type 1. Jpn J Cancer Res 87 (1996) 227-231
42. Wang Q., Chen Y., Xie F., Ge Y., Chen L., Wu H., et al. Development of a sandwich ELISA for evaluating soluble OX40L (CD252) in human sera of different ages or with Graves' disease. Cytokine 36 (2006) 23-28
43. Kim K.M., Kim H.W., Kim J.O., Beak K.M., Kim J.K., and Kang C.Y. Induction of 4-1BB (CD137) expression by DNA damaging agents in human T lymphocytes. Immunology 107 (2002) 472-479
44. Ma B.Y., Mikolajczak S.A., Danesh A., Hosiawa K.A., Cameron C.M., Takaori-Kondo A., et al. The expression and the regulatory role of OX40 and 4-1BB heterodimer in activated human T cells. Blood 106 (2005) 2002-2010