Enhanced detection of genetic association of hypertensive heart disease by analysis of latent phenotypes

Genetic Epidemiology

Volumn 32, Issue 6, 2008, Pages 528-538

  Gu, C Charles ^a   Flores, Hubert R ^a   de las Fuentes, Lisa ^a   Dávila Román, Victor G ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Candidate gene SNPs; Endophenotypes; Factor analysis; Genetic association; Hypertensive heart disease; ICA; Independent component analysis; Latent traits

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR;

ADULT; ANTHROPOMETRY; ARTICLE; COMORBIDITY; DIABETES MELLITUS; DYSLIPIDEMIA; ECHOCARDIOGRAPHY; ENVIRONMENTAL FACTOR; FEMALE; GENE FREQUENCY; GENE INTERACTION; GENETIC ASSOCIATION; GENOTYPE; HEART DISEASE; HEART LEFT VENTRICLE HYPERTROPHY; HEMODYNAMICS; HUMAN; HYPERTENSION; INDEPENDENT COMPONENT ANALYSIS; MAJOR CLINICAL STUDY; MALE; METABOLISM; OBESITY; PHENOTYPE; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AFRICAN AMERICANS; AGED; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPERTENSION; HYPERTROPHY, LEFT VENTRICULAR; MALE; MIDDLE AGED; MODELS, STATISTICAL; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT, HERITABLE; REGRESSION ANALYSIS; RISK FACTORS;

EID: 51749085049     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.20326     Document Type: Article

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