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Volumn 14, Issue 2, 2007, Pages 66-69

Hepatocyte growth factor and the hepatocyte growth factor receptor signalling complex as targets in cancer therapies

Author keywords

Cancer treatment; cMet; Hepatocyte growth factor; Targeting

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; BETA CATENIN; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; NEUTRALIZING ANTIBODY; NOTCH RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN INHIBITOR; PROTEIN TYROSINE KINASE; RAC PROTEIN; RHO FACTOR; RIBOZYME; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; SMALL INTERFERING RNA; STAT3 PROTEIN; WNT PROTEIN;

EID: 51649128339     PISSN: None     EISSN: 17187729     Source Type: Journal    
DOI: 10.3747/co.2007.108     Document Type: Article
Times cited : (6)

References (31)
  • 1
    • 0024427178 scopus 로고
    • Molecular cloning and expression of human hepatocyte growth factor
    • Nakamura T, Nishizawa T, Hagiya M, et al. Molecular cloning and expression of human hepatocyte growth factor. Nature 1989;342:440-3.
    • (1989) Nature , vol.342 , pp. 440-443
    • Nakamura, T.1    Nishizawa, T.2    Hagiya, M.3
  • 2
    • 0025351332 scopus 로고
    • Hepatocyte and scatter factor
    • Gherardi E, Stoker M. Hepatocyte and scatter factor. Nature 1990;346:228.
    • (1990) Nature , vol.346 , pp. 228
    • Gherardi, E.1    Stoker, M.2
  • 4
    • 33644694009 scopus 로고    scopus 로고
    • The potential lymphangiogenic effects of hepatocyte growth factor/scatter factor in vitro and in vivo
    • Jiang WG, Davies G, Martin TA, et al. The potential lymphangiogenic effects of hepatocyte growth factor/scatter factor in vitro and in vivo. Int J Mol Med 2005;16:723-8.
    • (2005) Int J Mol Med , vol.16 , pp. 723-728
    • Jiang, W.G.1    Davies, G.2    Martin, T.A.3
  • 5
    • 30544452034 scopus 로고    scopus 로고
    • Hepatocyte growth factor promotes lymphatic vessel formation and function
    • Kajiya K, Hirakawa S, Ma BJ, Drinnenberg I, Detmar M. Hepatocyte growth factor promotes lymphatic vessel formation and function. EMBO J 2005;24:2885-95.
    • (2005) EMBO J , vol.24 , pp. 2885-2895
    • Kajiya, K.1    Hirakawa, S.2    Ma, B.J.3    Drinnenberg, I.4    Detmar, M.5
  • 6
    • 33745465488 scopus 로고    scopus 로고
    • Hepatocyte growth factor and the Met system as a mediator of tumor - stromal interactions
    • Matsumoto K, Nakamura T. Hepatocyte growth factor and the Met system as a mediator of tumor - stromal interactions. Int J Cancer 2006;119:477-83.
    • (2006) Int J Cancer , vol.119 , pp. 477-483
    • Matsumoto, K.1    Nakamura, T.2
  • 7
    • 33646557679 scopus 로고    scopus 로고
    • A novel activating function of c-Src and Stat3 on HGF transcription in mammary carcinoma cells
    • Wojcik EJ, Sharifpoor S, Miller NA, et al. A novel activating function of c-Src and Stat3 on HGF transcription in mammary carcinoma cells. Oncogene 2006;25:2773-84.
    • (2006) Oncogene , vol.25 , pp. 2773-2784
    • Wojcik, E.J.1    Sharifpoor, S.2    Miller, N.A.3
  • 8
    • 10644279613 scopus 로고    scopus 로고
    • Constitutive hepatocyte growth factor - receptor (HGF R)/met tyrosine kinase activation is associated with cellular transformation independently of mutations within its tyrosine kinase and C-terminal domains (abstract)
    • Giannini G, Noel J. Constitutive hepatocyte growth factor - receptor (HGF R)/met tyrosine kinase activation is associated with cellular transformation independently of mutations within its tyrosine kinase and C-terminal domains (abstract). Mol Biol Cell 2002;13(suppl):875a.
    • (2002) Mol Biol Cell , vol.13 , Issue.SUPPL.
    • Giannini, G.1    Noel, J.2
  • 9
    • 30444451036 scopus 로고    scopus 로고
    • Functional analysis of HGF/ met signaling and aberrant HGF-activator expression in diffuse large B-cell lymphoma
    • Tjin EP, Groen RW, Vogelzang I, et al. Functional analysis of HGF/ met signaling and aberrant HGF-activator expression in diffuse large B-cell lymphoma. Blood 2006;107:760-8.
    • (2006) Blood , vol.107 , pp. 760-768
    • Tjin, E.P.1    Groen, R.W.2    Vogelzang, I.3
  • 10
    • 33847326735 scopus 로고    scopus 로고
    • Molecular co-expression of the c-met oncogene and hepatocyte growth factor in primary colon cancer predicts tumor stage and clinical outcome
    • in press
    • Kammula US, Kuntz EJ, Francone TD, et al. Molecular co-expression of the c-met oncogene and hepatocyte growth factor in primary colon cancer predicts tumor stage and clinical outcome. Cancer Lett 2006;[in press].
    • (2006) Cancer Lett
    • Kammula, U.S.1    Kuntz, E.J.2    Francone, T.D.3
  • 11
    • 33745220780 scopus 로고    scopus 로고
    • met-Regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype
    • Kaposi-Novak P, Lee JS, Gomez-Quiroz L, Coulouarn C, Factor VM, Thorgeirsson SS. met-Regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype. J Clin Invest 2006;116:1582-95.
    • (2006) J Clin Invest , vol.116 , pp. 1582-1595
    • Kaposi-Novak, P.1    Lee, J.S.2    Gomez-Quiroz, L.3    Coulouarn, C.4    Factor, V.M.5    Thorgeirsson, S.S.6
  • 12
    • 0033517060 scopus 로고    scopus 로고
    • Association of the HGF/SF receptor, c-Met, with the cell-surface adhesion molecule, E-cadherin and catenins in human tumor cells
    • Hiscox S, Jiang WG. Association of the HGF/SF receptor, c-Met, with the cell-surface adhesion molecule, E-cadherin and catenins in human tumor cells. Biochem Biophys Res Commun 1999;261:406-11.
    • (1999) Biochem Biophys Res Commun , vol.261 , pp. 406-411
    • Hiscox, S.1    Jiang, W.G.2
  • 13
    • 0035315829 scopus 로고    scopus 로고
    • HGF/SF modifies the interaction between c-Met and E-cadherin/catenin complex in prostate cancer cells
    • Davies G, Jiang WG, Mason MD. HGF/SF modifies the interaction between c-Met and E-cadherin/catenin complex in prostate cancer cells. Int J Mol Med 2001;7:385-8.
    • (2001) Int J Mol Med , vol.7 , pp. 385-388
    • Davies, G.1    Jiang, W.G.2    Mason, M.D.3
  • 14
    • 33847014441 scopus 로고    scopus 로고
    • A positive feedback loop between hepatocyte growth factor receptor and •- catenin sustains colorectal cancer cell invasive growth
    • Rasola A, Fassetta M, De Bacco F, et al. A positive feedback loop between hepatocyte growth factor receptor and •- catenin sustains colorectal cancer cell invasive growth. Oncogene 2007;26:1078-87.
    • (2007) Oncogene , vol.26 , pp. 1078-1087
    • Rasola, A.1    Fassetta, M.2    De Bacco, F.3
  • 15
    • 33748310896 scopus 로고    scopus 로고
    • Regulatory role of c-Met in insulin-like growth factor-I receptor-mediated migration and invasion of human pancreatic carcinoma cells
    • Bauer TW, Somcio RJ, Fan F, et al. Regulatory role of c-Met in insulin-like growth factor-I receptor-mediated migration and invasion of human pancreatic carcinoma cells. Mol Cancer Ther 2006;5:1676-82.
    • (2006) Mol Cancer Ther , vol.5 , pp. 1676-1682
    • Bauer, T.W.1    Somcio, R.J.2    Fan, F.3
  • 16
    • 3142707564 scopus 로고    scopus 로고
    • Reactive oxygen species mediate Met receptor transactivation by G protein-coupled receptors and the epidermal growth factor receptor in human carcinoma cells
    • Fischer OM, Giordano S, Comoglio PM, Ullrich A. Reactive oxygen species mediate Met receptor transactivation by G protein-coupled receptors and the epidermal growth factor receptor in human carcinoma cells. J Biol Chem 2004;279: 28970-8.
    • (2004) J Biol Chem , vol.279 , pp. 28970-28978
    • Fischer, O.M.1    Giordano, S.2    Comoglio, P.M.3    Ullrich, A.4
  • 17
    • 27944460443 scopus 로고    scopus 로고
    • The neurotrophin receptor TrkB cooperates with c-Met in enhancing neuroblastoma invasiveness
    • Hecht M, Schulte JH, Eggert A, Wilting J, Schweigerer L. The neurotrophin receptor TrkB cooperates with c-Met in enhancing neuroblastoma invasiveness. Carcinogenesis 2005;26: 2105-15.
    • (2005) Carcinogenesis , vol.26 , pp. 2105-2115
    • Hecht, M.1    Schulte, J.H.2    Eggert, A.3    Wilting, J.4    Schweigerer, L.5
  • 18
    • 27544478385 scopus 로고    scopus 로고
    • Mitogen-inducible gene 6 is an endogenous inhibitor of HGF/met-induced cell migration and neurite growth
    • Pante G, Thompson J, Lamballe F, et al. Mitogen-inducible gene 6 is an endogenous inhibitor of HGF/met-induced cell migration and neurite growth. J Cell Biol 2005;171:337-48.
    • (2005) J Cell Biol , vol.171 , pp. 337-348
    • Pante, G.1    Thompson, J.2    Lamballe, F.3
  • 19
  • 20
    • 3142736728 scopus 로고    scopus 로고
    • Overexpression of sprouty 2 inhibits HGF/SF-mediated cell growth, invasion, migration, and cytokinesis
    • Lee CC, Putnam AJ, Miranti CK, et al. Overexpression of sprouty 2 inhibits HGF/SF-mediated cell growth, invasion, migration, and cytokinesis. Oncogene 2004;23:5193-202.
    • (2004) Oncogene , vol.23 , pp. 5193-5202
    • Lee, C.C.1    Putnam, A.J.2    Miranti, C.K.3
  • 21
    • 33748997692 scopus 로고    scopus 로고
    • Leibowitz-Amit R, Tsarfaty G, Abargil Y, Yerushalmi GM, Horev J, Tsarfaty I. Mimp, a mitochondrial carrier homologue, inhibits met-HGF/SF-induced scattering and tumorigenicity by altering met-HGF/SF signaling pathways. Cancer Res 2006; 66:8687-97.
    • Leibowitz-Amit R, Tsarfaty G, Abargil Y, Yerushalmi GM, Horev J, Tsarfaty I. Mimp, a mitochondrial carrier homologue, inhibits met-HGF/SF-induced scattering and tumorigenicity by altering met-HGF/SF signaling pathways. Cancer Res 2006; 66:8687-97.
  • 22
    • 21244448682 scopus 로고    scopus 로고
    • Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers
    • Herter S, Piper DE, Aaron W, et al. Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers. Biochem J 2005;390:125-36.
    • (2005) Biochem J , vol.390 , pp. 125-136
    • Herter, S.1    Piper, D.E.2    Aaron, W.3
  • 23
    • 15544386767 scopus 로고    scopus 로고
    • Hepsin activates pro-hepatocyte growth factor and is inhibited by hepatocyte growth factor activator inhibitor-1B (Hai-1B) and Hai-2
    • Kirchhofer D, Peek M, Lipari MT, Billeci K, Fan B, Moran P. Hepsin activates pro-hepatocyte growth factor and is inhibited by hepatocyte growth factor activator inhibitor-1B (Hai-1B) and Hai-2. FEBS Lett 2005;579:1945-50.
    • (2005) FEBS Lett , vol.579 , pp. 1945-1950
    • Kirchhofer, D.1    Peek, M.2    Lipari, M.T.3    Billeci, K.4    Fan, B.5    Moran, P.6
  • 24
    • 24644447871 scopus 로고    scopus 로고
    • Serum hepatocyte growth factor activator (HGFA) in benign prostatic hyperplasia and prostate cancer
    • Nagakawa O, Yamagishi T, Fujiuchi Y, et al. Serum hepatocyte growth factor activator (HGFA) in benign prostatic hyperplasia and prostate cancer. Eur Urol 2005;48:686-90.
    • (2005) Eur Urol , vol.48 , pp. 686-690
    • Nagakawa, O.1    Yamagishi, T.2    Fujiuchi, Y.3
  • 25
    • 1642535487 scopus 로고    scopus 로고
    • The hepatocyte growth factor regulatory factors in human breast cancer
    • Parr C, Watkins G, Mansel RE, Jiang WG. The hepatocyte growth factor regulatory factors in human breast cancer. Clin Cancer Res 2004;10:202-11.
    • (2004) Clin Cancer Res , vol.10 , pp. 202-211
    • Parr, C.1    Watkins, G.2    Mansel, R.E.3    Jiang, W.G.4
  • 26
    • 27544498809 scopus 로고    scopus 로고
    • Induction of hepatocyte growth factor/scatter factor by fibroblast clustering directly promotes tumor cell invasiveness
    • Kankuri E, Cholujova D, Comajova M, Vaheri A, Bizik J. Induction of hepatocyte growth factor/scatter factor by fibroblast clustering directly promotes tumor cell invasiveness. Cancer Res 2005;65:9914-22.
    • (2005) Cancer Res , vol.65 , pp. 9914-9922
    • Kankuri, E.1    Cholujova, D.2    Comajova, M.3    Vaheri, A.4    Bizik, J.5
  • 27
    • 21144447438 scopus 로고    scopus 로고
    • Tumor suppressor activity and epigenetic inactivation of hepatocyte growth factor activator inhibitor type 2/SPINT2 in papillary and clear cell renal cell carcinoma
    • Morris MR, Gentle D, Abdulrahman M, et al. Tumor suppressor activity and epigenetic inactivation of hepatocyte growth factor activator inhibitor type 2/SPINT2 in papillary and clear cell renal cell carcinoma. Cancer Res 2005;65:4598-606.
    • (2005) Cancer Res , vol.65 , pp. 4598-4606
    • Morris, M.R.1    Gentle, D.2    Abdulrahman, M.3
  • 28
    • 0002704698 scopus 로고    scopus 로고
    • Radioimmunoscintigraphy of tumors autocrine for human met and hepatocyte growth factor/ scatter factor
    • Hay RV, Cao B, Skinner RS, et al. Radioimmunoscintigraphy of tumors autocrine for human met and hepatocyte growth factor/ scatter factor. Mol Imaging 2002;1:56-62.
    • (2002) Mol Imaging , vol.1 , pp. 56-62
    • Hay, R.V.1    Cao, B.2    Skinner, R.S.3
  • 29
    • 26444571830 scopus 로고    scopus 로고
    • Nuclear imaging of met-expressing human and canine cancer xenografts with radiolabeled monoclonal antibodies (MetSeek)
    • Hay RV, Cao B, Skinner RS, et al. Nuclear imaging of met-expressing human and canine cancer xenografts with radiolabeled monoclonal antibodies (MetSeek). Clin Cancer Res 2005;11(pt 2):7064s-9s.
    • (2005) Clin Cancer Res , vol.11 , Issue.PART 2
    • Hay, R.V.1    Cao, B.2    Skinner, R.S.3
  • 30
    • 0035875024 scopus 로고    scopus 로고
    • In vivo molecular imaging of met tyrosine kinase growth factor receptor activity in normal organs and breast tumors
    • Shaharabany M, Abramovitch R, Kushnir T, et al. In vivo molecular imaging of met tyrosine kinase growth factor receptor activity in normal organs and breast tumors. Cancer Res 2001;61:4873-8.
    • (2001) Cancer Res , vol.61 , pp. 4873-4878
    • Shaharabany, M.1    Abramovitch, R.2    Kushnir, T.3
  • 31
    • 34547749466 scopus 로고    scopus 로고
    • c-Met ectodomain shedding rate correlates with malignant potential
    • Athauda G, Giubellino A, Coleman JA, et al. c-Met ectodomain shedding rate correlates with malignant potential. Clin Cancer Res 2006;12(pt 1):4154-62.
    • (2006) Clin Cancer Res , vol.12 , Issue.PART 1 , pp. 4154-4162
    • Athauda, G.1    Giubellino, A.2    Coleman, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.