Antidiarrhoeal activity of the standardised extract of Cinnamomum tamala in experimental rats

Journal of Natural Medicines

Volumn 62, Issue 4, 2008, Pages 396-402

  Rao, Chandana Venkateswara ^a   Vijayakumar, Madhavan ^a   Sairam, K ^b   Kumar, Vikas ^b  

^a CSIR NATIONAL BOTANICAL RESEARCH INSTITUTE   (India)

^b BANARAS HINDU UNIVERSITY   (India)

Author keywords

Antidiarrhoeal; Cinnamomum tamala; Indian spice

Indexed keywords

ALCOHOL; ATROPINE; CASTOR OIL; CATALASE; CHARCOAL; CINNAMOMUM TAMALA EXTRACT; DIPHENOXYLATE; EUGENOL; PHENOLSULFONPHTHALEIN; PLANT EXTRACT; POTASSIUM ION; SODIUM CHLORIDE; SODIUM ION; SUPEROXIDE DISMUTASE; TANNIN; UNCLASSIFIED DRUG; YOHIMBINE;

ANGIOSPERM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROTECTION; CINNAMOMUM; CINNAMOMUM TAMALA; CONTROLLED STUDY; DEFECATION; DEGRANULATION; DIARRHEA; DOSE RESPONSE; DRUG ACTIVITY; ENZYME ACTIVITY; GASTROINTESTINAL SECRETION; GASTROINTESTINAL TRANSIT; IN VITRO STUDY; LIPID PEROXIDATION; MALE; MAST CELL; MESENTERY; NONHUMAN; PLANT LEAF; RAT; STOMACH EMPTYING;

ANIMALS; ANTIDIARRHEALS; CASTOR OIL; CELL DEGRANULATION; CHARCOAL; CINNAMOMUM; DIARRHEA; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GASTRIC EMPTYING; GASTROINTESTINAL TRANSIT; INDIA; MALE; MAST CELLS; PHENOLSULFONPHTHALEIN; PLANT EXTRACTS; POTASSIUM; RATS; RATS, SPRAGUE-DAWLEY; SODIUM;

EID: 51649109830     PISSN: 13403443     EISSN: 18610293     Source Type: Journal    
DOI: 10.1007/s11418-008-0258-8     Document Type: Article

References (25)

1. RM Showkat M Ali R Kapoor 2004 Chemical composition of essential oil of Cinnamomum tamala Nees et Eberm. Leaves Flavour Fragr J 19 112 114
2. SR Sharma SK Dwivedi D Swarup 1996 Hypoglycaemic and hypolipidemic effects of Cinnamomum tamala Nees leaves Indian J Exp Biol 34 372 374
3. TS Kujala JM Loponen KD Klika K Pihlaja 2000 Phenolics and betacyanins in red beetroot (Beta vulgaris) root: distribution and effect of cold storage on the content of total phenolics and three individual compounds J Agric Food Chem 48 5338 5342
4. L Melo G Thomas R Mukherjee 1988 Antidiarrhoeal activity of bisnordihydrotoxiferine isolated from root bark of Strychonus trinervis (Vell.) Mart J Pharm Pharmacol 40 79 82
5. C Scarpignato T Capovilla G Bertaccini 1980 Action of caerulein on gastric emptying of the conscious rat Arch Int Pharmacodyn 246 286 294
6. S Norton 1954 Quantitative determination of mast cell fragmentation of compound 48/80 Br J Pharmacol 9 494 497
7. F Awouters CJE Niemegeers FM Lenaerts PAJ Janssen 1978 Delay of castor oil-induced diarrhoea in rats; a new way to evaluate the prostaglandin synthesis J Pharm Pharmacol 30 41 45
8. OFC Nwodo EO Alumanah 1991 Studies on Abrus precatorious seed II: antidiarrhoeal activity J Ethnopharmacol 31 395 398
9. GD Lutterodt 1989 Inhibition of gastrointestinal release of acetylocholine by quercetine as a possible mode of action of Psidium guajava leaf extracts in the treatment of acute diarrhoeal disease J Ethnopharmacol 25 235 247
10. A Robert JE Nezamis C Lancaster AI Hanchar MS Klepper 1976 Enteropooling assay: a test for diarrhoea produced by prostaglandins Prostaglandins 11 809 814
11. G Di Carlo N Mascolo A Izzo F Capasso G Autore 1994 Effect of quercetin on gastrointestinal tract in rats and mice Phytother Res 8 42 45
12. IS Jamall JC Smith 1985 Effects of cadmium on glutathione peroxidase, superoxidase dismutase and lipid peroxidation in the rat heart: a possible mechanism of cadmium cardiotoxicity Toxicol Appl Pharmacol 80 33 42
13. Claiborne A (1985) Catalase activity. In: Greenwald RA (ed) CRS handbook of methods for oxygen radical research. CRC Press, Boca Raton, pp 283-284
14. M Nishikimi NA Rao K Yagi 1972 The occurrence of superoxide anion in the reaction of reduced PMS and molecular oxygen Biochem Biophys Res Commun 46 849 854
15. P Kakkar B Das PN Viswanathan 1984 Modified spectrophotometric assay of SOD Ind J Biochem Biophys 2 130 132
16. EB Brandt RT Strait D Hershko Q Wang 2003 Mast cells are required for experimental oral allergen-induced diarrhea J Clin Invest 112 1666 1677
17. MD Pulimood B Anna M Minnie MD Mathan 1998 Quantitative and ultrastructural analysis of rectal mucosal mast cells in acute infectious diarrhea Dig Dis Sci 43 2111 2116
18. GJM Smits A Romain 1996 Influence of aging on gastric emptying of liquids, small intestine transit, and fecal output in rats Exp Gerontol 31 589 596
19. KM Sanders 1984 Evidence that prostaglandins are local regulatory agents in canine ileal circular muscles Am J Physiol 246 G361 G366
20. Bruton LL (1985) Agent affecting gastrointestinal water flux and motility, digestants and bile acids. In: Gillman AG, Rall TW, Nies AS, Tayloy P (eds) The pharmacological basis of therapeutics. McGraw-Hill, New York, p 914
21. V Rao Ch Kartik R Amresh A Irfan AKS Rawat P Pushpangadan 2003 Protective effect of Aegle marmelos Correa fruit in gastrointestinal dysfunction in rats Pharm Biol 41 558 563
22. FG Shoba M Thomas 2001 Study of antidiarrhoeal activity of four medicinal plants in castor oil induced diarrhoea J Ethnopharmacol 76 73 76
23. S Manonmani S William S Subramanian S Govindaswamy 1991 Biochemical studies on the antidiarrhoeal effect of Cauvery-100, an ayurvedic formulation in rats Biochem Int 24 701 708
24. B Halliwell JMC Gutteridge CE Cross 1992 Free radicals, antioxidants and human diseases: where are we now J Lab Clin Med 119 598 620
25. I Fridovich 1986 Biological effects of superoxide radical Arch Biochem Biophys 247 1 11