Protective effect of Aegle marmelos fruit in gastrointestinal dysfunction in rats

Pharmaceutical Biology

Volumn 41, Issue 8, 2003, Pages 558-563

  Rao, Ch V ^a   Amresh, R Kartik ^a   Irfan, Aziz ^a   Rawat, A K S ^a   Pushpangadan, P ^a  

^a CSIR NATIONAL BOTANICAL RESEARCH INSTITUTE   (India)

Author keywords

Antidiarrhoeal; Antioxidants; Antiulcer; Bael; Lipid peroxidation

Indexed keywords

ACETYLSALICYLIC ACID; AEGLE MARMELOS EXTRACT; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ANTIDIARRHEAL AGENT; ANTIOXIDANT; ANTIULCER AGENT; CIMETIDINE; DIPHENOXYLATE; MALONALDEHYDE; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; YOHIMBINE;

ANIMAL CELL; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DIGESTIVE SYSTEM FUNCTION DISORDER; DRUG ACCUMULATION; DRUG EFFECT; FEMALE; FRUIT; GASTROINTESTINAL MUCOSA; IMMOBILIZATION STRESS; INTESTINE MOTILITY; LIPID PEROXIDATION; MALE; NONHUMAN; RAT; STOMACH MUCOSA; STRESS ULCER; TRADITIONAL MEDICINE;

AEGLE MARMELOS; ANIMALIA; CASTOR; CORREA;

EID: 9144242462     PISSN: 13880209     EISSN: None     Source Type: Journal    
DOI: 10.1080/13880200390501190     Document Type: Article

References (30)

1. Anonymous (1985): The Wealth of India (Raw materials), Vol. V. Council of Scientific and Industrial Research Publication, CSIR, New Delhi: 85-88.
2. Anonymous (1979): Diarrhoea disease control program. Weekly Epidemic Rec 16: 121.
3. Awouters F, Niemegeers CJE, Lenaerts FM, lanssen PAl (1978): Delay of castor oil induced diarrhoea in rats; a new way to evaluate the prostaglandin synthesis. J Pharm Pharmacol 30: 41-45.
4. Cho CH, Ogle CW, Dai S (1976): Acute gastric ulcer formation in response to electrical vagal stimulation in rats. Eur J Pharmacol 35: 215-219.
5. 2-receopor activation in stress ulceration in rats. Eur J Pharmacol 55: 23-33.
6. Chopra RN, Nayar SL, Chopra IC (1956): Glossary of Indian Medicinal Plants: Council of Scientific and Industrial Research, New Delhi: 258.
7. Das D, Banerjee RK (1993): Effect of stress on the antioxidant enzymes and gastric ulceration. Mol Cell Biochem 1125: 115-125.
8. Ferreira SJ, Vane JR (1974): New aspects of the model of actions of NSAIDs. Ann Rev Pharmacol 14: 57-70.
9. Flemstrom G, Turnberg LA (1984): Gastroduodenal defence mechanisms. Clin Gastroenterol 13: 327-354.
10. Fridovich I (1986): Biological effects of superoxide radical. Archives Biochem Biophysics 247: 1-11.
11. Goel RK, Govinda Das D, Sanyal AK (1985): Effect of vegetable banana powder on changes induced by ulcerogenic agents on dissolved nucosubstances in gastric juice. Indian J Gastroenterol 4: 249-251.
12. Goel RK, Maiti RN (1997): Antiulcer activity of naturally occurring pyranocoumarin and isocoumarins and their effect on the prostanoid synthesis using human colonic mucosa. India J Exp Biol 35: 1080-1083.
13. Hase T, Moss BJ (1973): Microvascular changes in gastric mucosain development of gastric ulcers in rats. Gastroenterology 65: 224-228.
14. Hollander D, Taranawski A, Krause WJ, Gergely H (1985): Protective effect of sucralfate against alcohol-induced gastric mucosal injury in the rat. Gastroenterology 88: 366-374.
15. Hsu WH (1982): Xylazine-induced delay in small intestine transit in mice. Euro J Pharmacol 83: 55-60.
16. Jamall IS, Smith JC (1985): Effects of cadmium on glutathione peroxidase, superoxidase dismutase and lipid peroxidation in the rat heart: a possible mechanism of cadmium cardiotoxicity. Toxicol Appl Pharmacol 80: 33-42.
17. Konturek SJ, Redecki T, Piastucki I, Brzozowski T, Drozdowicz D (1987): Gastroprotection by colloidal bismuth subcitrate (De-nol) and sucralfate. Role of endogenous prostaglandins. Gut 228: 201-205.
18. Lutterodt GD (1989): Inhibition of gastrointestinal release of acetylocholine by quercetine as a possible mode of action of Psidium guajava leaf extracts in the treatement of acute diarrhoeal disease. J Ethnopharmacol 25: 235-247.
19. Nwodo OFC, Alumanah EO (1991): Studies on Abrus precatorious seed II: Antidiarrhoeal activity. J Ethnopharmacol 31: 395-398.
20. Ohkawa H, Oshishi N, Yagi K (1979): Assay of lipid peroxidation in animal tissues by thiobarbituric acid reaction. Anal Biochem 95: 331-358.
21. Padmanabhapillai N, Ramaswamy S, Gopalakrishinan V, Ghosh MN (1982): Effect of cholinergic drugs on acute and chronic morphine dependence. Arch Int Pharmacodyn 257: 147-154.
22. 4 in rat gastric mucosa. Prostaglandins 31: 283-293.
23. Puri S, Ray A, Chakravarti AK, Sen P (1994): Role of dopaminergic mechanisms in the regulation of stress responses in experimental animals. Pharmacol Brachem Behav 48: 53-56.
24. Rao Ch V, Maiti RN, Goel RK (1999): Effect of mild irritant on gastric mucosal offensive and defensive factors. Indian J Physiol Pharmacol 44: 185-191.
25. Rao Ch V, Sairam K, Goel RK (2001): Experimental evaluation of Emblica officinalis fruits in gastric ulceration and secretion. Acta Pharmaceutica Turcica XLIII: 155-160.
26. Sairam K, Rao Ch V, Dora Babu M, Goel RK (2001): Prophylactic and curative effects of Bacopa monniera in gastric ulcer models. Phytomedicine 8: 423-430.
27. Sairam K, Rao Ch V, Dora Babu M, Vijay Kumar K, Goel RK (2002) Antiulcerogenic effect of methanolic extract of Emblica officinalis: An experimental study. J Ethnopharmacol 82: 1-9.
28. Shobha FG, Thomas M (2001): Study of antidiarrhoeal activity of four medicinal plants in castor oil induced diarrhoea. J Ethnopharmacol 76: 73-76.
29. Vane JR (1971): Inhibition of prostaglandin synthesis as a mechanism of action of aspirin like drugs. Nature New Biology 231: 232-235.
30. Zimmerman M (1983): Ethical guidelines for investigation of experimental pain in conscious animal. Pain 16: 109-110.