Rapid identification of triterpenoid saponins in the roots of Codonopsis lanceolata by liquid chromatography-mass spectrometry

Journal of Natural Medicines

Volumn 62, Issue 4, 2008, Pages 423-429

  Ichikawa, Makoto ^a   Ohta, Sanae ^a   Komoto, Noriko ^b   Ushijima, Mitsuyasu ^a   Kodera, Yukihiro ^a   Hayama, Minoru ^a   Shirota, Osamu ^c   Sekita, Setsuko ^c   Kuroyanagi, Masanori ^b  

^a WAKUNAGA PHARMACEUTICAL CO LTD   (Japan)

^b PREFECTURAL UNIVERSITY OF HIROSHIMA   (Japan)

^c TOKUSHIMA BUNRI UNIVERSITY   (Japan)

Author keywords

Codonopsis lanceolata; Lancemaside A; LC MS; Triterpenoid saponin

Indexed keywords

AGLYCONE; ANION; ASTER SAPONIN HB; CODONOPSIS EXTRACT; FOETIDISSIMOSIDE A; LANCEMASIDE A; LANCEMASIDE B; LANCEMASIDE C; LANCEMASIDE D; LANCEMASIDE E; LANCEMASIDE F; LANCEMASIDE G; OLIGOSACCHARIDE; SAPONIN DERIVATIVE; TRITERPENOID; UNCLASSIFIED DRUG;

ARTICLE; CODONOPSIS; CODONOPSIS LANCEOLATA; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG STRUCTURE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PLANT ROOT;

CHROMATOGRAPHY, LIQUID; CODONOPSIS; MASS SPECTROMETRY; PLANT ROOTS; SAPONINS; TRITERPENES;

EID: 51649101245     PISSN: 13403443     EISSN: 18610293     Source Type: Journal    
DOI: 10.1007/s11418-008-0270-z     Document Type: Article

References (12)

1. Sekita S, Kuroyanagi M, Yasuda K, Mizuno I, Ushijima M, Hayama M, Ichikawa M, Sumihiro M (2005) Drug for ameliorating male climacteric disorder. Patent WO200515426
2. M Ushijima N Komoto M Sugizono I Mizuno M Sumihiro M Ichikawa M Hayama N Kawahara T Nakane O Shirota S Sekita M Kuroyanagi 2008 Triterpene glycosides from the roots of Codonopsis lanceolata Chem Pharm Bull 56 308 314
3. Shirota O, Nagamatsu K, Sekita S, Komoto N, Kuroyanagi M, Ichikawa M, Ohta S, Ushijima M (2008) Preparative separation of the saponin lancemaside A from Codonopsis lanceolata by centrifugal partition chromatography. Phytochem Anal. http://www3.interscience.wiley.com/journal/118902185/abstract. doi: 10.1002/pca.1065
4. A Tava M Mella Z Bialy M Jurzysta 2003 Stability of saponins in alcoholic solutions: ester formation as artifacts J Agric Food Chem 51 1797 1800
5. AA Magid L Voutquenne D Harakat I Pouny C Catron C Moretti C Lavaud 2006 Triterpenoid saponins from the fruits of Caryocar villosum J Nat Prod 69 919 926
6. Y Itakura M Ichikawa Y Mori R Okino M Udayama T Morita 2001 How to distinguish garlic from the other Allium vegetables J Nutr 131 963S 967S
7. MJ Ahn J Kim 2005 Identification and quantification of steroidal saponins in Polygonatum species by HPLC/ESI/MS Arch Pharm Res 28 592 597
8. B Li Z Abliz M Tang G Fu S Yu 2006 Rapid structural characterization of triterpenoid saponins in crude extract from Symplocos chinensis using liquid chromatography combined with electrospray ionization tandem mass spectrometry J Chromatogr A 1101 53 62
9. JJ Balsevich GG Bishop I Ramirez-Erosa 2006 Analysis of bisdesmosidic saponins in Saponaria vaccaria L. by HPLC-PAD-MS: identification of new quillaic acid and gypsogenin 3-O-trisaccharides Phytochem Anal 17 414 423
10. S Broberg LI Nord L Kenne 2004 Oligosaccharide sequences in Quillaja saponins by electrospray ionization ion trap multiple-stage mass spectrometry J Mass Spectrom 39 691 701
11. L Liu Y Zhou Z Wu L Ding 2006 ESI-QqTOF-MS/MS and APCI-IT-MS/MS analysis of steroid saponins from the rhizomes of Dioscorea panthaica J Mass Spectrom 41 1 22
12. S Liu M Cui Z Liu F Song 2004 Structural analysis of saponins from medicinal herbs using electrospray ionization tandem mass spectrometry J Am Soc Mass Spectrom 15 133 141